Relationship between Vitamin D Insufficient, Vitamin D Deficient Pakistani population and COVID-19

Sana Mahmood; Nasima Zafar; Nargis Anjum; Kauser Abbas Saldera; Ufaque Batool K. Samo; Talha Shahid

doi:10.53730/ijhs.v7nS1.14191

Authors

Sana Mahmood Department of Physiology, Hamdard College of Medicine & Dentistry, Hamdard University, Karachi, Pakistan
Nasima Zafar Department of Physiology, Hamdard College of Medicine & Dentistry, Hamdard University, Karachi, Pakistan
Nargis Anjum Department of Physiology, Karachi Medical & Dental College (KMDC), Karachi, Pakistan
Kauser Abbas Saldera Department of Physiology, CIMS, Gambat, Pakistan
Ufaque Batool K. Samo Department of Physiology, BMSI, Jinnah Postgraduate Medical Centre, Karachi, Pakistan
Talha Shahid Department of Anesthesiology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan

Keywords:

Vitamin D Deficient, COVID-19, Relationship

Abstract

The people with less Vitamin D have enlarged probability for acute respiratory tract infections. There is substantial uncertainty about the link between “25(OH)D” ratio and the prevalence of “COVID-19”. With the major endpoints of death, duration of staying in hospital, cannulation and rate of recurrence of COV-19 indicators, this study was done to evaluate the quantity of Vit-D in Corona patients in Jinnah post graduate medical Centre Krachi, Pakistan, and to link “vitamin D” insufficiency and shortage with these events. Eighty patients in total had their “25(OH)D” status assessed throughout the duration of their COVID-19 disease. Deficient (9 nanogram/milliliter), inadequate (5-35 ng/mL), or appropriate (> 25 ng/mL) 25-hydroxyvitamin D levels were determined. Patients in ICU (P = 0.035), protruding oxygen supply (P = 0.03), tenacious eosinophilic pneumonia, and decease were all substantially correlated with “Vit-D” insufficiency in univariate Cox regression. After adjusting for confounding variables, only death (P = 0.039) and persistent pulmonary infiltrates (probability = 0.008) were statistically substantial on multivariate Cox regression. Moreover, affected population having 25(OH)D concentrations 9.9 ng/mL showed a better likelihood of surviving than others. Populations lacking in 25-hydroxyvitamin D experienced lower results and a long duration of hospital stay.

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