Antibiotic resistance between theory and reality

Updated vision on the ecological phenomenon and the emerging crisis recommendations

Authors

  • Berghiche A Institute of Agronomy and Veterinary Science, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria & Laboratory of Science and Technique of Living, Institute of Agronomic and Veterinarian Sciences, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria
  • Asnoune Z University Chadli Bend Djedid El Tarf, Algeria
  • Labiad I Institute of Agronomy and Veterinary Science, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria & Laboratory of Science and Technique of Living, Institute of Agronomic and Veterinarian Sciences, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria
  • Bouzid R Laboratory of agriculture and ecosystems fonctionnary, University Chadli Bend Djedid El Tarf, Algeria & University Chadli Bend Djedid El Tarf, Algeria

Keywords:

antibiotics, resistance, risk, impact, ecological disorders

Abstract

Our work includes two aspects of resistance in consequence, the first one is the evolutionary side as it evolves in our ecosystem, as well as the estimative side for the future, where it poses a huge challenge that is still unpredictable.  Our scientific opinion on this subject starts with a synthetic overview of mechanisms that may be recognized until now, and demonstrates the evolutionary concept in the context of resistance. The inadequate use of antibiotics for preventive or zootechnical purposes in animal production can lead to the presence of their residues as well as to the emergence of multi-resistant bacteria, even though the passage of this bacterial survival pattern among species and even across different species creates health risks and ecological disorders in general. However, the current problem, requiring urgent focus and attention, could become more and more critical, and the timing of intervention can put our lives at risk. So the question arises, when will we take action?

Downloads

Download data is not yet available.

References

Abeer, S. (2012). Future medicine: nanomedicine. Jimsa, 25(3), 187-192.‏

Allen, H. K., Trachsel, J., Looft, T., & Casey, T. A. (2014). Finding alternatives to antibiotics. Annals of the New York Academy of Sciences, 1323(1), 91-100.‏

Amábile-Cuevas, C. F., & Chicurel, M. E. (1992). Bacterial plasmids and gene flux. Cell, 70(2), 189-199.‏

Anadón, A., Martínez-Larrañaga, M. R., Ares, I., & Martínez, M. A. (2018). Regulatory aspects for the drugs and chemicals used in food-producing animals in the European Union. In Veterinary toxicology (pp. 103-131). Academic Press.

Bandow, Julia Elisabeth, et al. "Proteomic approach to understanding antibiotic action." Antimicrobial agents and chemotherapy 47.3 (2003): 948-955.‏

Baumgartner, J. C., Siqueira, J. F., Sedgley, C. M., & Kishen, A. (2008). Microbiology of endodontic disease. Ingle’s endodontics, 6, 221-308.‏

Berdy, J. (2005). Bioactive microbial metabolites. The Journal of antibiotics, 58(1), 1-26.‏

Berghiche, A. (2019). Special attention is needed for reduce antibiotic residue risk in the white meat produced in Algeria. Journal of food quality and hazards control, 6(2), 44-44.‏

Bouvet, P., Cavaillon, J. M., Dussaule, J. C., Gay, S., Gosselin, M. P., Merel, Q., ... & Senni, N. (2022). La résistance aux antibiotiques. Les Cahiers de l'ANR.‏

Chinemerem Nwobodo, D., Ugwu, M. C., Oliseloke Anie, C., Al‐Ouqaili, M. T., Chinedu Ikem, J., Victor Chigozie, U., & Saki, M. (2022). Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace. Journal of Clinical Laboratory Analysis, 36(9), e24655.‏

Christaki, E., Marcou, M., & Tofarides, A. (2020). Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence. Journal of molecular evolution, 88, 26-40.‏

Christaki, E., Marcou, M., & Tofarides, A. (2020). Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence. Journal of molecular evolution, 88, 26-40.‏

Christensen, Søren Brøgger. "Drugs that changed society: History and current status of the early antibiotics: Salvarsan, sulfonamides, and β-lactams." Molecules 26.19 (2021): 6057.‏

Das, D., & Goyal, A. (2012). Lactic acid bacteria in food industry. Microorganisms in sustainable agriculture and biotechnology, 757-772.‏

Daubin, V. (2002). Phylogénie et évolution des génomes procaryotes (Doctoral dissertation, Université Claude Bernard-Lyon I).‏

Davies, J., & Davies, D. (2010). Origins and evolution of antibiotic resistance. Microbiology and molecular biology reviews, 74(3), 417-433.‏

De la Cruz, F., & Davies, J. (2000). Horizontal gene transfer and the origin of species: lessons from bacteria. Trends in microbiology, 8(3), 128-133.‏

Defoirdt, T., Sorgeloos, P., & Bossier, P. (2011). Alternatives to antibiotics for the control of bacterial disease in aquaculture. Current opinion in microbiology, 14(3), 251-258.‏

Dhama, K., Chakraborty, S., Kapoor, S., Tiwari, R., Kumar, A., Deb, R., ... & Natesan, S. (2013). One world, one health-veterinary perspectives. Adv Anim Vet Sci, 1(1), 5-13.‏

Diwan, V., Tamhankar, A. J., Khandal, R. K., Sen, S., Aggarwal, M., Marothi, Y., ... & Stålsby-Lundborg, C. (2010). Antibiotics and antibiotic-resistant bacteria in waters associated with a hospital in Ujjain, India. BMC public health, 10(1), 1-8.‏

Donné, J., & Dewilde, S. (2015). The challenging world of biofilm physiology. In Advances in microbial physiology (Vol. 67, pp. 235-292). Academic Press.‏

Fair, R. J., & Tor, Y. (2014). Antibiotics and bacterial resistance in the 21st century. Perspectives in medicinal chemistry, 6, PMC-S14459.‏

Foster, T. J. (1983). Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria. Microbiological reviews, 47(3), 361-409.‏

Foster, T. J. (2017). Antibiotic resistance in Staphylococcus aureus. Current status and future prospects. FEMS microbiology reviews, 41(3), 430-449.‏

George, S., Sharma, R. K., Hazarika, R., Hazarika, S., Ahmed, R., & Phangchopi, D. (2023). Predatory Bacteria: A Novel Approach to Antibiotic Substitution. International Journal of Bio-Resource & Stress Management, 14(1).‏

Gilliland, S. E. (1990). Health and nutritional benefits from lactic acid bacteria. FEMS Microbiology reviews, 7(1-2), 175-188.‏

Gootz, T. D. (1990). Discovery and development of new antimicrobial agents. Clinical microbiology reviews, 3(1), 13-31.‏

Hansen, L. H., Mauvais, P., & Douthwaite, S. (1999). The macrolide–ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Molecular microbiology, 31(2), 623-631.‏

Holmes, A. H., Moore, L. S., Sundsfjord, A., Steinbakk, M., Regmi, S., Karkey, A., ... & Piddock, L. J. (2016). Understanding the mechanisms and drivers of antimicrobial resistance. The Lancet, 387(10014), 176-187.‏

Jarlier, V., & Nikaido, H. (1994). Mycobacterial cell wall: structure and role in natural resistance to antibiotics. FEMS microbiology letters, 123(1-2), 11-18.‏

Jian, Z., Zeng, L., Xu, T., Sun, S., Yan, S., Yang, L., ... & Dou, T. (2021). Antibiotic resistance genes in bacteria: Occurrence, spread, and control. Journal of Basic Microbiology, 61(12), 1049-1070.‏

Jin, K. (2020). Developing cyclic peptide-based drug candidates: an overview. Future medicinal chemistry, 12(19), 1687-1690.‏

Kapoor, Garima, Saurabh Saigal, and Ashok Elongavan. "Action and resistance mechanisms of antibiotics: A guide for clinicians." Journal of anaesthesiology, clinical pharmacology 33.3 (2017): 300.‏

Khan, H., Flint, S., & Yu, P. L. (2010). Enterocins in food preservation. International journal of food microbiology, 141(1-2), 1-10.‏

Kraemer, S. A., Ramachandran, A., & Perron, G. G. (2019). Antibiotic pollution in the environment: from microbial ecology to public policy. Microorganisms, 7(6), 180.‏

Kumar, A., Gupta, K., Dixit, S., Mishra, K., & Srivastava, S. (2019). A review on positive and negative impacts of nanotechnology in agriculture. International Journal of Environmental Science and Technology, 16, 2175-2184.‏

Lai, S., Zhang, Q., & Jin, L. (2023). Natural and Man-Made Cyclic Peptide-Based Antibiotics. Antibiotics, 12(1), 42.‏

Land, K. M., & Johnson, P. J. (1999). Molecular basis of metronidazole resistance in pathogenic bacteria and protozoa. Drug Resistance Updates, 2(5), 289-294.‏

Le, H., Karakasyan, C., Jouenne, T., Le Cerf, D., & Dé, E. (2021). Application of polymeric nanocarriers for enhancing the bioavailability of antibiotics at the target site and overcoming antimicrobial resistance. Applied Sciences, 11(22), 10695.‏

Lesch, John E. The first miracle drugs: how the sulfa drugs transformed medicine. Oxford University Press, USA, 2007.‏

Levy, S. B. (2013). The antibiotic paradox: how miracle drugs are destroying the miracle. Springer.‏

Levy, Stuart B. The antibiotic paradox: how miracle drugs are destroying the miracle. Springer, 2013.‏

Littmann, Jasper, Adrian M. Viens, and Diego S. Silva. "The super-wicked problem of antimicrobial resistance." Ethics and drug resistance: Collective responsibility for global public health 5 (2020).‏

Loc-Carrillo, C., & Abedon, S. T. (2011). Pros and cons of phage therapy. Bacteriophage, 1(2), 111-114.‏

Mack, A., Relman, D. A., & Choffnes, E. R. (Eds.). (2011). Antibiotic resistance: implications for global health and novel intervention strategies: workshop summary. National Academies Press.‏

Manyi-Loh, C., Mamphweli, S., Meyer, E., & Okoh, A. (2018). Antibiotic use in agriculture and its consequential resistance in environmental sources: potential public health implications. Molecules, 23(4), 795.‏

Marini, E., Di Giulio, M., Magi, G., Di Lodovico, S., Cimarelli, M. E., Brenciani, A., ... & Facinelli, B. (2018). Curcumin, an antibiotic resistance breaker against a multiresistant clinical isolate of Mycobacterium abscessus. Phytotherapy research, 32(3), 488-495.‏

McManus, M. C. (1997). Mechanisms of bacterial resistance to antimicrobial agents. American Journal of Health-System Pharmacy, 54(12), 1420-1433.‏

Neu, H. C., & Gootz, T. D. (1996). Antimicrobial chemotherapy. Medical Microbiology. 4th edition.‏

Onorato, M. R. (2021). Genome-Scale Metabolic Modeling of Mycobacterium tuberculosis (Doctoral dissertation, San Diego State University).‏

Parada, J. L., Caron, C. R., Medeiros, A. B. P., & Soccol, C. R. (2007). Bacteriocins from lactic acid bacteria: purification, properties and use as biopreservatives. Brazilian archives of Biology and Technology, 50, 512-542.‏

Pérez, J., Contreras-Moreno, F. J., Marcos-Torres, F. J., Moraleda-Muñoz, A., & Muñoz-Dorado, J. (2020). The antibiotic crisis: How bacterial predators can help. Computational and Structural Biotechnology Journal, 18, 2547-2555.‏

Perez, R. H., Zendo, T., & Sonomoto, K. (2014). Novel bacteriocins from lactic acid bacteria (LAB): various structures and applications. Microbial cell factories, 13(1), 1-13.‏

Pormohammad, A., Monych, N. K., Ghosh, S., Turner, D. L., & Turner, R. J. (2021). Nanomaterials in wound healing and infection control. Antibiotics, 10(5), 473.‏

Ravelli, Q. (2014). Résistances aux antibiotiques: la fin du scientisme de l’innovation. Bulletin d’histoire et d’épistémologie des sciences de la vie, 21(2), 149-161.‏

Ruppé, É. (2018). Les antibiotiques: c'est la panique!: Les solutions pour lutter contre la résistance des bactéries…. Editions Quae.‏

Shahid, M., Sobia, F., Singh, A., Khan, H. M., Hawkey, P. M., Huq, A., & Khardori, N. (2009). AmpC β-lactamases and bacterial resistance: an updated mini review. Reviews and Research in Medical Microbiology, 20(3), 41-55.‏

Srivastava, S. K. (2016). Nano particles: emerging warheads against bacterial superbugs. Current Topics in Medicinal Chemistry, 16, 1963-1975.‏

Stearns, S. C., Nesse, R. M., Govindaraju, D. R., & Ellison, P. T. (2010). Evolutionary perspectives on health and medicine. Proceedings of the National Academy of Sciences, 107(suppl_1), 1691-1695.‏

Šušković, J., Kos, B., Beganović, J., Leboš Pavunc, A., Habjanič, K., & Matošić, S. (2010). Antimicrobial activity–the most important property of probiotic and starter lactic acid bacteria. Food Technology and Biotechnology, 48(3), 296-307.‏

Svircev, A., Roach, D., & Castle, A. (2018). Framing the future with bacteriophages in agriculture. Viruses, 10(5), 218.‏

Todar, K. (2011). Bacterial resistance to antibiotics (page 3). Todar’s online textbook of bacteriology, 4.‏

Uddin, T. M., Chakraborty, A. J., Khusro, A., Zidan, B. R. M., Mitra, S., Emran, T. B., ... & Koirala, N. (2021). Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects. Journal of infection and public health, 14(12), 1750-1766.‏

Valladão, G. M. R., Gallani, S. U., & Pilarski, F. (2015). Phytotherapy as an alternative for treating fish disease. Journal of veterinary pharmacology and therapeutics, 38(5), 417-428.‏

Waglechner, N., & Wright, G. D. (2017). Antibiotic resistance: it’s bad, but why isn’t it worse?. BMC biology, 15(1), 1-8.‏

Walsh, Christopher. Antibiotics: actions, origins, resistance. American Society for Microbiology (ASM), 2003.‏

Wright, G. D. (2007). The antibiotic resistome: the nexus of chemical and genetic diversity. Nature reviews microbiology, 5(3), 175-186.‏

Yao, J. D., & Moellering Jr, R. C. (2011). Antibacterial agents. Manual of clinical microbiology, 1041-1081.‏

Yi, D., Bayer, T., Badenhorst, C. P., Wu, S., Doerr, M., Höhne, M., & Bornscheuer, U. T. (2021). Recent trends in biocatalysis. Chemical Society Reviews, 50(14), 8003-8049.‏

Yılmaz, Ç., & Özcengiz, G. (2017). Antibiotics: Pharmacokinetics, toxicity, resistance and multidrug efflux pumps. Biochemical pharmacology, 133, 43-62.‏

Zeise, K. D., Woods, R. J., & Huffnagle, G. B. (2021). Interplay between Candida albicans and lactic acid bacteria in the gastrointestinal tract: impact on colonization resistance, microbial carriage, opportunistic infection, and host immunity. Clinical microbiology reviews, 34(4), e00323-20.‏

Zimina, M., Babich, O., Prosekov, A., Sukhikh, S., Ivanova, S., Shevchenko, M., & Noskova, S. (2020). Overview of global trends in classification, methods of preparation and application of bacteriocins. Antibiotics, 9(9), 553.‏

Published

25-08-2023

How to Cite

Berghiche, A., Asnoune, Z., Labiad, I., & Bouzid, R. (2023). Antibiotic resistance between theory and reality: Updated vision on the ecological phenomenon and the emerging crisis recommendations. International Journal of Health Sciences, 7(S1), 2460–2475. Retrieved from https://sciencescholar.us/journal/index.php/ijhs/article/view/14531

Issue

Section

Peer Review Articles

Most read articles by the same author(s)