Carcinogenic effects of antibiotic residues in meat

Clinical and statistical perspective

Authors

  • Amine Berghiche Institute of Agronomy and Veterinary Science, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria & Laboratory of Science and Technique of Living, Institute of Agronomic and Veterinarian Sciences, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria
  • Ibtissem Labiad Institute of Agronomy and Veterinary Science, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria & Laboratory of Science and Technique of Living, Institute of Agronomic and Veterinarian Sciences, University Mohamed Cherif Messaâdia, Souk Ahras, Algeria
  • Bouzid Riad Laboratory of agriculture and ecosystems fonctionnary, University Chadli Bend Djedid El Tarf, Algeria & University Chadli Bend Djedid El Tarf, Algeria

Keywords:

antibiotics residues, clinical perspective, statistical perspective, impact, Cohorte

Abstract

Through this research note we focused on the subject of the link between the use of antibiotics and its residues in the human and animal body and the appearance of tumors. A clinical and statistical perspective is conducted in our note, through examples of literature that have discussed this topic in which the impact of some antibiotics is determined theoretically and the interdiction of some molecules is made in some countries, but in fact and statistically the application of adequate etiological study "cohort" in order to correlate the causes and effects is failed because the conditions of feasibility is incomplete or poorly defined. In vitro studies, modeling and docking are required to confirm or affirm the hypotheses about the subject.

Downloads

Download data is not yet available.

References

Chokshi, A., Sifri, Z., Cennimo, D., & Horng, H. (2019). Global contributors to antibiotic resistance. Journal of global infectious diseases, 11(1), 36.

Berghiche, A., Khenenou, T., Kouzi, A., & Labiad, I. (2018). An investigation on the predominant diseases, its diagnosis, and commonly used drugs in the poultry farms in the North-Eastern regions of Algeria. Veterinary world, 11(7), 986.

Sköld, O. (2011). Antibiotics and antibiotic resistance. John Wiley & Sons.

Malfertheiner, P., Sipponen, P., Naumann, M., Moayyedi, P., Mégraud, F., Xiao, S. D., ... & Nyrén, O. (2005). Helicobacter pylori eradication has the potential to prevent gastric cancer: a state-of-the-art critique. Official journal of the American College of Gastroenterology| ACG, 100(9), 2100-2115.

Silver, L. L., & Bostian, K. A. (1993). Discovery and development of new antibiotics: the problem of antibiotic resistance. Antimicrobial agents and chemotherapy, 37(3), 377-383.

Benigni, R., & Bossa, C. (2011). Mechanisms of chemical carcinogenicity and mutagenicity: a review with implications for predictive toxicology. Chemical reviews, 111(4), 2507-2536.

Barrett, J. C. (1993). Mechanisms of multistep carcinogenesis and carcinogen risk assessment. Environmental health perspectives, 100, 9-20.

Cohen, S. M., & Ellwein, L. B. (1991). Genetic errors, cell proliferation, and carcinogenesis. Cancer research, 51(24), 6493-6505.

Pascal, G. (1991). Safety assessment in relation to additives. Food Policy Trends in Europe: Nutrition, Technology, Analysis and Safety, 178.

Westendorf, J., Marquardt, H., & Marquardt, H. (1982). Anthracycline antitumor antibiotics: Their carcinogenicity and their mutagenicity. In Anthracycline antibiotics in cancer therapy (pp. 30-49). Springer, Dordrecht.

Bacanlı, M., & Başaran, N. (2019). Importance of antibiotic residues in animal food. Food and Chemical Toxicology, 125, 462-466.

Jaegerstad, M., & Skog, K. (2005). Genotoxicity of heat-processed foods. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 574(1-2), 156-172.

Dinh, Q. T., Munoz, G., Duy, S. V., Do, D. T., Bayen, S., & Sauvé, S. (2020). Analysis of sulfonamides, fluoroquinolones, tetracyclines, triphenylmethane dyes and other veterinary drug residues in cultured and wild seafood sold in Montreal, Canada. Journal of Food Composition and Analysis, 94, 103630.

Tsai, M. Y., Lin, C. F., Yang, W. C., Lin, C. T., Hung, K. H., & Chang, G. R. (2019). Health risk assessment of banned veterinary drugs and quinolone residues in shrimp through liquid chromatography–tandem mass spectrometry. Applied Sciences, 9(12), 2463.

Khan, M., & Lively, J. A. (2020). Determination of sulfite and antimicrobial residue in imported shrimp to the USA. Aquaculture Reports, 18, 100529.

Hanekamp, J. C., & Bast, A. (2015). Antibiotics exposure and health risks: chloramphenicol. Environmental toxicology and pharmacology, 39(1), 213-220.

Ehrenberg, L., & Osterman‐Golkar, S. (1981). Alkylation of macromolecules for detecting mutagenic agents. Teratogenesis, carcinogenesis, and mutagenesis, 1(1), 105-127.

Bauer, G. (2012). Tumor cell-protective catalase as a novel target for rational therapeutic approaches based on specific intercellular ROS signaling. Anticancer research, 32(7), 2599-2624.

Guengerich, F. P. (2008). Cytochrome p450 and chemical toxicology. Chemical research in toxicology, 21(1), 70-83.

Hansen, L. G., & Shane, B. S. (2019). Xenobiotic metabolism. In Basic environmental toxicology (pp. 49-105). CRC Press.

Lieber, C. S. (1997). Cytochrome P-4502E1: its physiological and pathological role. Physiological reviews, 77(2), 517-544.

Sheweita, S. A. (2000). Drug-metabolizing enzymes mechanisms and functions. Current drug metabolism, 1(2), 107-132.

Whitlock Jr, J. P. (1986). The regulation of cytochrome P-450 gene expression. Annual review of pharmacology and toxicology, 26(1), 333-369.

Horsfall Jr, F. L. (1963). Current concepts of cancer. Canadian Medical Association journal, 89(24), 1224.

Kovacic, P., & Somanathan, R. (2014). Nitroaromatic compounds: Environmental toxicity, carcinogenicity, mutagenicity, therapy and mechanism. Journal of Applied Toxicology, 34(8), 810-824.

Mital, A. (2009). Synthetic nitroimidazoles: biological activities and mutagenicity relationships. Scientia pharmaceutica, 77(3), 497-520.

Gatnik, M. F. (2016). Computational Methods in Support of Chemical Risk Assessment. Liverpool John Moores University (United Kingdom).

Dayan, A. D. (1993). Allergy to antimicrobial residues in food: assessment of the risk to man. Veterinary microbiology, 35(3-4), 213-226.

Quan, S. F., Howard, B. V., Iber, C., Kiley, J. P., Nieto, F. J., O'Connor, G. T., ... & Wahl, P. W. (1997). The sleep heart health study: design, rationale, and methods. Sleep, 20(12), 1077-1085.

Setia, M. S. (2016). Methodology series module 1: Cohort studies. Indian journal of dermatology, 61(1), 21.

Amine, B. (2021). STATISTICS & MEDICINE: THE EXACT LINK. Global Journal of Public Health Medicine, 3(2), 409-413.

Petrelli, F., Ghidini, M., Ghidini, A., Perego, G., Cabiddu, M., Khakoo, S., ... & Zaniboni, A. (2019). Use of antibiotics and risk of cancer: a systematic review and meta-analysis of observational studies. Cancers, 11(8), 1174.

Published

25-08-2023

How to Cite

Berghiche, A., Labiad, I., & Riad, B. (2023). Carcinogenic effects of antibiotic residues in meat: Clinical and statistical perspective. International Journal of Health Sciences, 7(S1), 2493–2497. Retrieved from https://sciencescholar.us/journal/index.php/ijhs/article/view/14532

Issue

Section

Peer Review Articles

Most read articles by the same author(s)