Unraveling the connection: Hepatitis C Virus (HCV) and Acute Myelogenous Leukemia (AML) in the absence of antiviral therapy
A case report and literature review
Keywords:
Hepatitis C Virus, Pancytopenia, Acute Myelogenous Leukemia, HCV Complication, Case Report, Rare complication, oncologyAbstract
This case report presents a 40-year-old female with no prior medical history, who presented with symptoms of low-grade fever, shortness of breath, weakness, and pancytopenia. Upon examination, signs of chronic hepatitis C virus (HCV) infection with decompensated cirrhosis and acute myelogenous leukemia (AML) were evident. The patient did not receive any prior treatment for HCV. The case discussion explores the association between HCV infection and the development of AML, considering existing literature suggesting both direct viral effects and potential effects of HCV antiviral drugs on AML development. Despite collaborative efforts from hematology and oncology specialists, the patient's advanced AML stage precluded specific leukemia therapy. She succumbed to complications related to cirrhosis despite intensive care. This case emphasize the importance of investigating pancytopenia in patients with HCV, highlighting AML as a potential complication, whether due to the virus itself or its treatment, warranting further research.
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