Assessment of antibiotic resistance patterns in enteric fever patients
A systematic review and meta analysis
Keywords:
Enteric fever, Antibiotic resistance, Resistance patterns, Enteric pathogens, Treatment outcomes, Multi-drug resistance, SurveillanceAbstract
Enteric fever, caused by Salmonella enterica serovars Typhi and Paratyphi. Hence, it poses challenges in diagnosis and treatment due to variable clinical presentation and increasing antibiotic resistance. This systematic review and meta-analysis assess antibiotic resistance patterns in enteric fever patients. While discussing diagnostic methods, treatment modalities, and preventive strategies. The current literature highlights diagnostic challenges despite advancements, emphasizing the need for improved tools. So, antimicrobial resistance, particularly among younger populations, underscores the urgency for interventions. Therefore, region-specific investigation is crucial, especially for international travelers. While cephalosporins are key in treatment, tailored therapy based on local resistance patterns is required significantly. Hence prevention through vaccination and understanding carbohydrate-mediated infection strategies offers promise. Thus, further research is significantly required to address these challenges effectively and reduce the global burden of enteric infections. This study followed rigorous methodology, including systematic search strategies, quality assessment of studies, and adherence to reporting guidelines. Moreover, ethical considerations were addressed, and the protocol was registered. Overall, the study provides valuable insights into the multifaceted challenges of enteric fever and emphasizes the importance of collaborative efforts to mitigate its impact on global health.
Downloads
References
Briggs, N., Campbell, S., & Gupta, S. (2021). Advances in rapid diagnostics for bloodstream infections. Diagnostic Microbiology and Infectious Disease, 99(1), 115219.
Britto, C. D., Wong, V. K., Dougan, G., & Pollard, A. J. (2018). A systematic review of antimicrobial resistance in Salmonella enterica serovar Typhi, the etiological agent of typhoid. PLoS neglected tropical diseases, 12(10), e0006779.
Carey, M. E., Dyson, Z. A., Ingle, D. J., Amir, A., Aworh, M. K., Chattaway, M. A., Chew, K. L., Crump, J. A., Feasey, N. A., & Howden, B. P. (2023). Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes. Elife, 12, e85867.
Das, S., Mohakud, N. K., Suar, M., & Sahu, B. R. (2018). Vaccine development for enteric bacterial pathogens: Where do we stand? Pathogens and disease, 76(5), fty057.
Ducarmon, Q., Zwittink, R., Hornung, B., Van Schaik, W., Young, V., & Kuijper, E. (2019). Gut microbiota and colonization resistance against bacterial enteric infection. Microbiology and Molecular Biology Reviews, 83(3), 10.1128/mmbr. 00007-00019.
Hagmann, S. H., Angelo, K. M., Huits, R., Plewes, K., Eperon, G., Grobusch, M. P., McCarthy, A., Libman, M., Caumes, E., & Leung, D. T. (2020). Epidemiological and clinical characteristics of international travelers with enteric fever and antibiotic resistance profiles of their isolates: a GeoSentinel analysis. Antimicrobial agents and chemotherapy, 64(11), 10.1128/aac. 01084-01020.
Hendriksen, R. S., Bortolaia, V., Tate, H., Tyson, G. H., Aarestrup, F. M., & McDermott, P. F. (2019). Using genomics to track global antimicrobial resistance. Frontiers in public health, 7, 478239.
Javed, H., Hussain, K., Bashir, T., Ijaz, U., & Khoso, I. (2018). Diagnostic Accuracy Of Typhidot In Patients Of Typhoid Fever: Diagnostic Accuracy of Typhidot. Pakistan Armed Forces Medical Journal, 68(5), 1215-1218.
Leonard, H., Colodner, R., Halachmi, S., & Segal, E. (2018). Recent advances in the race to design a rapid diagnostic test for antimicrobial resistance. ACS sensors, 3(11), 2202-2217.
Longley, A. T., Hemlock, C., Date, K., Luby, S. P., Andrews, J. R., Saha, S. K., Bogoch, I. I., Yousafzai, M. T., Garrett, D. O., & Qamar, F. N. (2020). Illness severity and outcomes among enteric fever cases from Bangladesh, Nepal, and Pakistan: data from the Surveillance for Enteric Fever in Asia Project, 2016–2019. Clinical Infectious Diseases, 71(Supplement_3), S222-S231.
Neupane, D. P., Dulal, H. P., & Song, J. (2021). Enteric fever diagnosis: current challenges and future directions. Pathogens, 10(4), 410.
Organization, W. H. (2018). WHO report on surveillance of antibiotic consumption: 2016-2018 early implementation.
Pulingam, T., Parumasivam, T., Gazzali, A. M., Sulaiman, A. M., Chee, J. Y., Lakshmanan, M., Chin, C. F., & Sudesh, K. (2022). Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome. European Journal of Pharmaceutical Sciences, 170, 106103.
Pustake, M., Giri, P., Tambolkar, S., & Nayak, S. (2022). Extensively drug-resistant typhoid fever: A call to action. Indian Journal of Community Medicine, 47(1), 153-154.
Qamar, F. N., Yousafzai, M. T., Dehraj, I. F., Shakoor, S., Irfan, S., Hotwani, A., Hunzai, M. J., Thobani, R. S., Rahman, N., & Mehmood, J. (2020). Antimicrobial resistance in typhoidal Salmonella: surveillance for enteric fever in Asia project, 2016–2019. Clinical Infectious Diseases, 71(Supplement_3), S276-S284.
Raju, R., Angelin, J. K., Karthikeyan, A. S., Kumar, D., Kumar, R. R., Sahai, N., Ramanujan, K., Murhekar, M., Elangovan, A., & Samuel, P. (2021). Healthcare utilisation survey as part of the Hybrid model of the Surveillance of Enteric Fever in India (SEFI) study: processes, results, and challenges. medRxiv, 2021.2002. 2027.21252424.
Rauf, T., Rabbia Anam, M. S. A., & Farhan Rasheed, M. M. Comparative Effectiveness of Antibiotic Therapies in the Management of Typhoid Fever.
Rijpkema, S., & Bolgiano, B. (2021). Recent Developments in Enteric Bacterial Vaccines. Microorganisms, 9(8), 1604.
Roope, L. S., Smith, R. D., Pouwels, K. B., Buchanan, J., Abel, L., Eibich, P., Butler, C. C., Tan, P. S., Walker, A. S., & Robotham, J. V. (2019). The challenge of antimicrobial resistance: what economics can contribute. Science, 364(6435), eaau4679.
Saha, T., Arisoyin, A. E., Bollu, B., Ashok, T., Babu, A., Issani, A., Jhaveri, S., & Avanthika, C. (2023). Enteric Fever: Diagnostic Challenges and the Importance of Early Intervention. Cureus, 15(7).
Siontis, K. C., Noseworthy, P. A., Attia, Z. I., & Friedman, P. A. (2021). Artificial intelligence-enhanced electrocardiography in cardiovascular disease management. Nature Reviews Cardiology, 18(7), 465-478.
Sulis, G., Sayood, S., & Gandra, S. (2022). Antimicrobial resistance in low-and middle-income countries: current status and future directions. Expert review of anti-infective therapy, 20(2), 147-160.
Published
How to Cite
Issue
Section
Copyright (c) 2023 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
