Exploring the nutraceutical elixirs of commercial fruit and vegetables and wild edible plants with ethnomedicinal importance
Review article
Keywords:
Nutraceuticals, Antioxidants, Anti-inflammatory, Anti-diabetic, Wild edible plantsAbstract
The increasing emphasis on preventive healthcare has sparked interest in nutraceuticals, which bridge the gap between nutrition and pharmaceuticals. Nutraceuticals, including functional foods, supplements, and herbal products, are gaining popularity for their targeted health benefits, reflecting a societal shift towards proactive health management. Defined by the Food Safety and Standards Authority of India, nutraceuticals provide health benefits beyond basic nutrition and are increasingly valued for their preventive and therapeutic properties. This review explores the nutraceutical potential of fruits, vegetables, and wild edible plants, highlighting their diverse bioactive compounds. Fruits and vegetables are rich in phytochemicals like minerals, vitamins, dietary fiber, and bioactive compounds such as flavonoids, contributing to their nutraceutical potential. Focusing on fruits like mango, pineapple, citrus, and berries like strawberry and blueberry, the discussion underscores their role in enhancing overall well-being. Studies on specific vegetables such as tomato, garlic, moringa, etc., highlight their diverse health benefits, including antioxidant and anti-inflammatory properties. Research on wild edible fruits and vegetables among tribal populations in India reveals their nutritional and therapeutic significance, providing insights into their ethnomedicinal uses.
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Ahamed TS, Priya,VV, Gayathri R, Geetha RV (2016) Evaluation of antimicrobial activity of pineapple extract against selected oral pathogen. J Pharm Sci Res 8(6):491-492
Ahmad A, Padhye S, Sarkar FH (2012) Role of novel nutraceuticals garcinol, plumbagin and mangiferin in the prevention and therapy of human malignancies: Mechanisms of anticancer activity. In: Sarkar FH (ed). Nutraceuticals Cancer, Springer Science and Business Media, 380p
Ahmadi H, Nayeri Z, Minuchehr Z, Sabouni F, Mohammadi M (2020) Betanin purification from red beetroots and evaluation of its antioxidant and anti-inflammatory activity on LPS-activated microglial cells. PLos One 15(5):e0233088
Ahmed FA and Ali RFM (2013) Bioactive compounds and antioxidant activity of fresh and processed white cauliflower. Biomed Research Internation, 367819. doi: https://doi.org/10.1155/2013/367819
Ajaikumar KB, Asheef M, Babu BH, Padikkala J (2005) The inhibition of gastric mucosal injury by Punica granatum L. (pomegranate) methanolic ex tract. J Ethnopharmaco 96:171-176
Alajil O, Sagar VR, Kaur C, Rudra SG, Sharma RR, Kaushik R, Verma MK, Tomar M, Kumar M Mekhemar M (2021) Nutritional and phytochemical traits of apricots (Prunus armeniaca L.) for application in nutraceutical and health industry. Foods 10(6):1344
Ali ZA and Bilal A (2023) Efficacy assessment of beetroot extract in regulating iron deficiency anaemia in anaemic rats. Pak J Sci 75(1):88-93
Aliahmadi M, Amiri F, Bahrami LS, Hosseini AF, Abiri B, Vafa M (2021) Effects of raw red beetroot consumption on metabolic markers and cognitive function in type 2 diabetes patients. J Diabetes metabolic disorders, 20:673-682. doi: 10.1007/s40200-021-00798-z
Amorim JL, Simas DLR, Pinheiro MMG, Moreno DSA, Alviano CS, da Silva AJR Fernandes PD (2016) Anti-inflammatory properties and chemical characterisation of the essential oils of four Citrus species. PLOS One 11(4):e0153643. doi: 10.1371/journal.pone.0153643
Aravind G, Bhowmik DSD, Harish G (2013) Traditional and Medicinal Uses of Carica papaya. J. Med. Plants Stud 1:7–15
Arias BA, Ramon-Laca L (2005) Pharmacological properties of citrus and their ancient and medieval uses in the Mediterranean region. J Ethnopharmaco 97(1):89-95
Babu PN, Nagaraju B, Yamini K, Dhananhaneyulu M, Venkateswarlu K, Mubin M (2014) Evaluation of antidepressant activity of ethanolic extract of Dacus carota in mice. J Pharma Sci Res, 6(2):73-77
Bahrami R, Ghobadi A, Behnoud N, Akhtari E (2018) Medicinal properties of Daucus carota in traditional Persian medicine and modern phytotherapy. J Biochem technol, Special issue 2:107-114
Bajaj S, Urooj A and Prabhasankar P (2016) Antioxidative properties of mint (Mentha spicata L.) and its application in biscuits. Current Res Nutrition Food Sci J 4(3):209-216
Barreca D, Lagana G, Ficarra S, Tellone E, Leuzzi U, Galtieri A, Belloco E (2011) Evaluation of the antioxidant and cytoprotective properties of the exotic fruit Annona cherimola Mill. (Annonaceae). Food Res Inter 44(7):2302-2310
Bhardwaj A, Satpathy G and Gupta RK (2014) Preliminary screening of nutraceutical potential of Annona squamosa, an underutilized exotic fruit of India and its uses as a valuable source in functional foods. J Pharmacog Phytochem 3(2):172-180
Bhattacharya A, Ghosal S, Bhattacharya SK (2000). Antioxidant activity of tannoid principles of Emblica officinalis (amla) in chronic stress induced changes in rat brain. Indian J Exp Biol 38(9):877-880
Bhui K, Prasad S, George J Shukla Y (2009) Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumour-initiation triggering mitochondrial death pathway. Cancer Letters 282(2):167-176
Binu S (2010) Wild edible plants used by the tribals in Pathanamthitta district, Kerala. Indian J Trad Knowledge 9(2):309-312
Bishayee A, Sarkar A, Chatterjee M (1995) Hepatoprotective activity of carrot (Dacus carota L.) against carbon tetrachloride intoxication in mouse liver. J Ethnopharmaco 47(2):69-74
Biworo A, Tanjung E, Iskandar, Khairina, Suhartono (2015) Antidiabetic and antioxidant activity of jackfruit (Artocarpus heterophyllus) extract. J Medical Bioeng 4(4):318-323
Bowen-Forbes CS, Zhang Y, Nair MG (2010) Anthocyanin content, antioxidant, anti-inflammatory and anticancer properties blackberry and raspberry fruits. J Food Composition Analysis 23:554-560
Boyer J, Liu RH (2004) Apple phytochemicals and their health benefits. Nutri J 3(5):5. doi: 10.1186/1475-2891-3-5
Calvindi J, Syukur M, Nurcholis W (2020). Investigation of biochemical characters and antioxidant properties of different winged bean (Psophocarpus tetragonolobus) genotypes grown in Indonesia. Biodiversitas J Biological Diversity 21(6):2420-2424
Castillo-Lopez RI, Leon-Felix J, Angulo-Escalante MA, Gutierrez-Dorado R, Muy-Rangel MD, Heredia JB (2017) Nutritional and phenolic characterization of Moringa oleifera leaves grown in Sinaloa, Mexico. Pak J Botany 49(1):161-168
Celik I, Temur A, Isik I (2009) Hepatoprotective role and antioxidant capacity of pomegranate (Punica granatum) flowers infusion against trichloroacetic acid-exposed in rats. Food Chemical Toxicology 47:145-149
Chabib L, Suryani A, Dewi LS, Noviani H, Maharani WHP, Indraswari (2023) Pineaplle fruit extract (Ananas comosus L. Merr) as an antioxidant and anti-ane agent made with the nano-emulsion gel delivery system. Pharmacy Education 23(2):126–132. doi: https://doi.org/10.46542/pe.2023.232.126132
Chelliah R, Ramakrishnan S, Antony U (2017) Nutritional quality of Moringa oleifera for its bioactivity and antibacterial properties. Inter Food Res J 24(2):825
Chen CF, Li YD, Xu Z (2010) Chemical principles and bioactivities of blueberry. Yao Xue Xue Bao 45(4):422-429
Chen Y, Hwang W, Fang TJ, Cheng YH, Lin J (2010) The impact of transgenic papaya (TPY10-4) fruit supplementation on immune responses in ovalbumin-sensitised mice. J Sci Food Agri 91(3):539-546. doi: https://doi.org/10.1002/jsfa.4218
Chen H, Jiao H, Cheng Y, Xu K, Jia X, Shi Q, Guo S, Wang M, Du L, Wang F (2016) In vitro and in vivo immunomodulatory activity of okra (Abelmoschus esculentus L.) polysaccharides. J Medicinal Food 19(3):253-265
Chingsuwanrote P, Muangnoi C, Parengam K, Tuntipopipat S (2016) Antioxidant and anti-inflammatory activities of durian and rambutan pulp extract. Inter Food Res J 23(3):939-947
Cuellar-Nuñez ML, Luzardo-Ocampo I, Campos-Vega R, Gallegos-Corona MA, De Mejía EG, Loarca-Piña G (2018) Physicochemical and nutraceutical properties of moringa (Moringa oleifera) leaves and their effects in an in vivo AOM/DSS-induced colorectal carcinogenesis model. Food Res Inter 105:159-168
Curcic MG, Stankovic MS, Radojevic ID, Stefanovic OD, Comic LR, Topuzovic MD, Djacic DS, Markovic SD (2012) Biological effects, total phenolic content and flavonoid concentrations of fragrant yellow onion (Allium flavum L.). Medicinal Chem 8(1):46-51
Das D, Pal K, Sahana N, Mondal P, Das A, Chowdhury S, Mandal S, Pandit GK (2023) Evaluation of morphological and biochemical parameters and antioxidant activity and profiling of volatile compounds in fifteen Dolichos bean (Lablab purpureus L.) genotypes of India. Food Chem Advances 2:100164
Dimitry MY, Emmanuel PA, Edith DMJ, Armand AB, Nicolas NY (2021) Antioxidant property, anti-inflammatory and analgesic effects of aqueous extracts of two onion bulbs varieties (Allium cepa L.). Clinical Phytosci 7:49 doi: 10.1186/s40816-021-00284-2
Dinu M, Băbeanu C, Hoza G, Sima R, Soare R (2021) Nutraceutical value and production of the sweet potato (Ipomoea batatas L.) cultivated in South-West of Romania. J Central European Agri, 22(2):285-294
Dolkar D, Bakshi P, Wali VK, Sharma V, Shah RA (2017) Fruits as nutraceuticals. Eco. Environ. Cons. 23:S113-S118
Dougnon TJ, Kpodekon, TM, Laleye A, Ahissou H, Loko F (2011) Effect of pineapple (Ananas comosus) on haematological and biochemical parameters in albinos Wistar rats intoxicated with Doliprane. African J Biotechnol 10(28):5418-5422
Du G, Jin L, Han X, Song Z, Zhang H, Liang W (2009) Naringenin: A potential immunomodulator for inhibiting lung fibrosis and metastasis. Cancer Res 69(7):3205-3212
Ebeid HM, Gibriel AAY, Al-Sayed HM, Elbehairy SA, Motawe EH (2015) Hepatoprotective and antioxidant effects of wheat, carrot and mango as nutraceutical agents against CCl4-induced hepatocellular toxicity. J American College Nutri 34(3):228-231
El-Desouky SK, Ryu SY, Kim YK (2008) A new cytotoxic acylated apigenin glucoside from Phyllanthus emblica L. Natural Product Res 22(1):91-95
Frias-Moreno M, Parra-Quezada RA, Ruiz-Carrizales J, Gonzalez-Aguilar GA, Sepulveda D, Molina-Corral FJ, Jacobo-Cuellar JL, Olivas GI (2021) Quality, bioactive compounds and antioxidant capacity of raspberries cultivated in northern Mexico. Inter J Food Properties 24(1):603-614
Fumagalli M (2018) Strawberry ((Fragaria x ananassa Duch) tannins as ingredients of nutraceuticals with potential anti-gastritis properties. Department of Pharmacological and biomolecular Sciences, PhD Thesis 106p
Gajalakshmi S, Vijayalakshmi S, Rajeswari DV (2012) Phytochemical and pharmacological properties of Annona muricata: A review. Inter J Pharmacy Pharma Sci 4(2):3-6
Gea-Botella S, Moreno-Chamba B, de la Casa L, Salazar-Bermeo J, Martí N, Martínez-Madrid MC, Valero M and Saura D (2021) Carotenoids from Persimmon (Diospyros kaki Thunb.) Byproducts Exert Photoprotective, Antioxidative and Microbial Anti-Adhesive Effects on HaCaT. Pharmaceutics, 13(11):1898
Gentile C, Reig C, Corona O, Todaro A, Mazzaglia A, Perrone A, Gianguzzi G, Agusti M, Farina V (2016) Pomological traits, sensory profile and nutraceutical properties of nine cultivars of loquat (Eriobotrya japonica Lindl.) fruits grown in Mediterranean area. Plant foods human nutrition, 71:330-338
Ghada B, Pereira E, Pinela J, Prieto MA, Pereira C, Calhelha RC, Stojković D, Sokóvić M, Zaghdoudi K, Barros L, Ferreira IC (2020) Recovery of anthocyanins from passion fruit epicarp for food colorants: Extraction process optimization and evaluation of bioactive properties. Molecules, 25(14):3203
Ghasemzadeh A, Jaafar HZ, Rahmat A, Devarajan T (2014) Evaluation of bioactive compounds, pharmaceutical quality, and anticancer activity of curry leaf (Murraya koenigii L.). Evidence-based complementary altern medi e873803
Giampieri F, Tulipani S, Alvarez-Suarez JM, Quiles J, Mezzetti B, Battino M (2012) The strawberry: Composition, nutritional quality and impact on human health. Nutrition, 28(1):9-19
Giampieri F, Alvarez-Suarez JM, Mazzoni L, Romandini S, Bompadre S, Diamanti J, Capocasa F, Mezzetti B, Quiles JL, Ferreiro MS, et al. (2013) The potential impact of strawberry on human health. Natural Product Res 27(4-5):448-455
Gondi M, Rao UJSP (2015) Ethanol extract of mango (Mangifera indica L.) peel inhibits amylase and -glucosidase activities and ameliorates diabetes related biochemical parameters in streptozotocin (STZ)-induced diabetic rats. J Food Sci Technol 52:7883-7893
Gupta P, Bansal MP, Koul A (2013) Evaluating the effect of lycopene from Lycopersicum esculentum on apoptosis during NDEA induced hepatocarcinogens. Biochem Biophysical Res Communications 434(3):479-485
Hazarika TK, Lalramchuana, Nautiyal BP (2012) Studies on wild edible fruits of Mizoram, India used as ethno-medicine. Genetic Resources Crop Revolution 59(8): 1767-1776. doi: 10.1007/s10722-012-9799-5
Hossain MF, Akhtar S, Anwar M (2015) Nutritional value and medicinal benefits of pineapple. Intern J Nutri Food Sci 4(1):84-88
Hu J, Hu Y, Hu Y, Zheng S (2015) Intake of cruciferous vegetables is associated with reduced risk of ovarian cancer: A meta-analysis. Asian Paci J Clinical Nutrition 24(1):101-109
Huang J, Wu C, Hou RC, Jeng K (2008) Bromelain inhibits lipopolysaccharide-induced cytokine production in human THP-1 monocytes via the removal of CD14. J Molecular Cellular Immunol 37 (4):263-277
Huang CS, Chuang CH, Lo TF, Hu ML (2013) Anti-angiogenic effects of lycopene through immunomodulation of cytokine secretion in human peripheral blood mononuclear cells. J Nutritional Biochem 24(2):428-434
Huang CZ, Tung YT, Hsia SM, Wu CH, Yen GC (2017) The hepatoprotective effect of Phyllanthus emblica L. fruit on high fat diet-induced non-alcoholic fatty liver disease (NAFLD) in SD rats. Food Funct 8(2):842-850
Huber GM, Rupasinghe HPV (2009) Phenolic profiles and antioxidant properties of apple skin extracts. J Food Sci 74(9): C693-C700. doi: https://doi.org/10.1111/j.1750-3841.2009.01356.x
Jin L, Zeng W, Zhang C, Liang W (2017) Naringenin ameliorates acute inflammation by regulating intracellular cytokine degradation. J Immunol 199(10):3466-3477
Jiin WH, Hidayat EM, Lukman KA (2014) Gastroprotective effect of carrot (Daucus carota L.) juice in rat models. Althea Medical J 1(1):35-39
Ji-Young H, Su-Hyun S, Hyen-Joo P, Yong-Jin C, Jae-Ho P, Sang-Kook L (2008) Antioxidant, anti-inflammatory and antiproliferative activities of strawberry extracts. Biomolecules Therapeutics 16(3):286-292
Joshi N, Jain N, Pathak A, Singh J, Prasad R, Upadhyaya CP (2018) Biosynthesis of silver nanoparticles using Carissa carandas berries and its potential antibacterial activities. J Sol-Gel Sci Technol 86:682-689
Kabir Y, Shekhar HU, Sidhu JS (2017) Phytochemical compounds in functional properties of mangoes. In: Siddiq, M, Brecht JK, Sidhu JS (eds). Handbook of mango fruit: Production, postharvest science, processing technology and nutrition, Wiley Publisher, pp.237-254
Kang DM, Kwon JM, Jeong WJ, Jung YJ, Kang KK, Ahn MJ (2022) Antioxidant constituents and activities of the pulp with skin of Korean tomato cultivars. Molecules, 27(24):8741
Karuna MSL, Prasad RBN (2015) Vegetable-oil based nutraceuticals. In: Bahadur, B., Venkat Rajam, M., Sahijram, L., and Krishnamurthy, K. (eds), Plant Biol Biotechnol, Springer, New Delhi pp: 793-812
Kataya HAH, Hamza AA (2008) Red cabbage (Brassica oleracea) ameliorates diabetic nephropathy in rats. Evidence based complem alternative med 5(3): 281-287. Doi: 10.1093/ecam/nem029
Khan SMD, Ravikumar V, Neelima K (2011) Pharmacological intervention of the fruit of plant Ananas comosus acting as wound healing agent in various animal models. Int. J. Pharm. Technol. 3:1807-1824
Kim S, Kim DB, Jin W, Park J, Yoon W, Lee Y, Kim S, Lee S, Kim S, Lee OH, Shin, D (2018) Comparative studies of bioactive organosulphur compounds and antioxidant activities in garlic (Allium sativum L.), elephant garlic (Allium ampeloprasum L.) and onion (Allium cepa L.). Natural product res 32(10):1193-1197
Kovarovič J, Bystrická J, Tomáš J, Lenková M (2017). The influence of variety on the content of bioactive compounds in beetroot (Beta vulgaris L.) Potravinarstvo Slovak. J Food Sci 11(1):106-112
Kumar BR, Anupam A, Manchikanti P, Rameshbabu AP, Dasgupta S, Dhara S (2018) Identification and characterization of bioactive phenolic constituents, anti-proliferative, and anti-angiogenic activity of stem extracts of Basella alba and rubra. J food sci technol 55:1675-1684
Kumar S, Jena PK (2016) Tools from biodiversity: wild nutraceutical plants. In: Furze, J. N., Gupta, A. K., Reynolds, D. M., McClatchey, R., and Swing, K., (eds), Mathematical Adv Sustainable Environ Sys, Springer International Publishing, 347p
Kumari A, Chawla N, Dhatt AS (2018) Genotypic differences for anthocyanins in different parts of eggplant (Solanum melongena L.). Inter J Adv Res Biological Sci 5(1):12-18
Kwon RS, Lee GY, Lee S, Song J (2024) Antimicrobial properties of tomato juice and peptides against typhoidal Salmonella. Microbiol Spectrum 12(3): e03102-e03123. doi: https://doi.org/10.1128/spectrum 03102-23
Lee JH, Lee YB, Seo WD, Kang ST, Lim JW, Cho KM (2012) Comparative studies of antioxidant activities and nutritional constituents of persimmon juice (Diospyros kaki L. cv. Gapjubaekmok). Preventive Nutri Food Sci 17(2):141
Lei F, Tao JL, Su H, Xing DM, Lin H, Du LJ (2007) An evaluation of anti-obesity and anti-hyperlipidemia of pomegranate tannins using hierarchy program. World Sci Technol – Modernization Trad Chinese Med 9:46-50
Les F, Prieto JM, Arbones-Mainar JM, Valero MS, Lopez V (2015) Bioactive properties of commercialised pomegranate (Punica granatum) juice: antioxidant, antiproliferative and enzyme inhibiting activities. Food Function 6(6):2049-2057
Li WM, Ao MZ, Yu LJ, Ding P (2006) Microwave assisted extraction and antioxidation of seed oil of Punica granatum. Natural Product Research and Development, 18:378-380
Li Y, Chen D, Chu C, Li S, Chen Y, Wu C, Lin, C (2015) Naringenin inhibits dendritic cell maturation and has therapeutic effects in a murine model of collagen-induced arthritis. J Nutritional Biochem 26(12):1467-1478
Li Z, Lee HW, Liang X, Liang D, Wang Q, Huang D, Ong CN (2018) Profiling of phenolic compounds and antioxidant activity of 12 cruciferous vegetables. Molecules 23(5):1139
Lin CN, Lu CM, Huang PL (2000) Flavanoids from Artocarpus heterophyllus. Phytochemistry 39(6):1447-1451
Lin T, Wu Y, Chang H, Huang C, Cheng K, Hsu H, Hsieh C (2023) Anti-inflammatory and anti-oxidative effects of polysaccharides extracted from unripe Carica papaya L. fruit. Antioxidants 12(8):1506. doi: https://doi.org/10.3390/antiox12081506
Liu X, Cui C, Zhao M, Wang J, Luo W, Yang B, Jiang Y (2008) Identification of phenolics in the fruit of emblica (Phyllanthus emblica L.) and their antioxidant activities. Food Chem 109:909–915
Lucic D, Pavlovic I, Brkljacic L, Bogdanovic S, Farkas V, Cedilak A, Nanic L, Rubelj I, Salopek-Sondi B (2023) Antioxidant and antiproliferative activities of kale (Brassica oleracea var. acephala DC.) and wild cabbage (Brassica incana Ten.) polyphenolic extracts. Molecules 28(4):1840
Luna-Vázquez FJ, Ibarra-Alvarado C, Rojas-Molina A, Rojas-Molina JI, Yahia EM, Rivera-Pastrana DM, Rojas-Molina A, Zavala-Sánchez MÁ (2013) Nutraceutical value of black cherry Prunus serotina Ehrh. fruits: antioxidant and antihypertensive properties. Molecules 18(12):14597-14612
Mairuae N, Cheepsunthorn P, Cheepsunthorn CL, Tongjaroenbuangam W (2017) Okra (Abelmoschus esculentus Linn) inhibits lipopolysaccharide-induced inflammatory mediators in BV2 micrglial cells. Tropical J Pharma Res 16(6):1285-1292
Maisarah AM, Nurul AB, Asmah R, Fauziah O (2013) Antioxidant analysis of different parts of Carica papaya. Inter Food Res J 20(3): 1043-1048
Manthey JA, Grohmann K (1998) Flavonoids of the orange subfamily aurantoidae. In: Manthey, J. A. and Buslig, B. S. (eds). Flavonoids in the living system. Advances in Experimental Medicine and Biology, Springer, Boston
Manthey JA, Najla G, Grohmann K (2001) Biological properties of citrus flavonoids pertaining to cancer and inflammation. Current Medicinal Chem 8(2):135-153. doi: 10.2174/0929867013373723
Mazzoni L, Giampieri F, Alvarez-Suarez JM, Gasparrini M, Mezzetti B, Hernandez TYF, Battino MA (2019) Isolation of strawberry anthocyanin-rich fractions and their mechanisms of action against murine breast cancer cell lines. Food Function, 10: 7103-7120
Mi-Ran Y, Chang-Hee K, Bu HJ (2017) Antioxidant and anti-inflammatory activity of extracts from red beet (Beta vulgaris) root. Food Sci Preserv 24(3): 413-420. doi: https://doi.org/10.11002/kjfp.2017.24.3.413
Mohamadin AM, Elberry AA, Mariee AD, Morsy GM, Al-Abbasy FA (2012) Lycopene attenuates oxidative stress and heart lysosomal damage in isoproterenol induced cardiotoxicity in rats: A biochemical study. Pathophysiol 19(2):121-130
Muhammad I, Matazu IK, Yaradua IA, Yau S, Nasir A, Bilbis SL, Abbas YA (2018) Development of okra-based antidiabetic nutraceutical formulation from Abelmoschu esculentus L. Moench (Ex-maradi variety). Trop J Natural Product Res 2(2):80-86
Negro C, Aprile A, De Bellis L, Miceli A (2019) Nutraceutical properties of mulberries grown in southern Italy (Apulia). Antioxidants 8(7):223
Neuhofer H, Bachmann P, Witte L, Czygan FC (1989) The occurrence of pelletierine derivatives in Punica granatum. Planta Medica 55(7): 604. doi: 10.1055/s-2006-962147
Oboh G, Ademiluyi AO, Agunloye OM, Ademosun AO, Ogunsakin BG (2018) Inhibitory effect of garlic, purple onion and white onion on key enzymes linked with type 2 diabetes and hypertension. J Dietary Supplements pp:105-118. doi: https://doi.org/10.1080/19390211.2018.1438553
Oladeji O, Taiwo K, Gbadamosi S, Oladeji B, Ishola M, (2017) Studies on chemical constituents and nutrients bioavailability in Moringa oleifera leaf and seed. J Scientific Res Reports 14(1):1-12
Olorunnipa TA, Igbokwe CC, Lawal TO, Adeniyi BA, Mahady GB (2013). Clinical Microbiol: Open Access 2(7):1000132
Peñalver R, Martínez-Zamora L, Lorenzo JM, Ros G, Nieto G (2022) Nutritional and antioxidant properties of Moringa oleifera leaves in functional foods. Foods 11(8):1107
Popiolek-Kalisz J, Gliobowski P, Solarska E (2024) Supplementation of nutraceuticals from dwarf kiwi and apple improves lipid profile in overweight adults. Applied Sciences 14(4): 1324. doi: https://doi.org/10.3390/app14041324
Pradeepkumar T, Indira V, Sankar M (2013) Nutritional evaluation of wild leafy vegetables consumed by tribals in the Wayanad district of Kerala. In: Proceedings of the national academy of sciences, India Section B: Biological sciences, Allahabad, India. doi: 10.1007/s40011-013-0271-x
Prakoso YA, Rini CS, Wirjaatmadja R (2018) Efficacy of Aloe vera, Ananas comosus, and Sansevieria masoniana cream on the skin wound infected with MRSA. Adv Pharmacological Pharma Sci 4670569. doi: https://doi.org/10.1155/2018/4670569
Punia S, Kumar M (2021) Litchi (Litchi chinenis) seed: Nutritional profile, bioactivities, and its industrial applications. Trends Food Sci Technol 108:58-70
Rana GZ, Kirsten B, Malcolm RC, Christine LLM (2012) Effects of bioactive compounds from carrots (Daucus carota L.), polyacetylenes, beta-carotene and lutein on human lymphoid leukaemia cells. Anticancer Agents Medicinal Chem 12(6):640-652
Ranasinghe RASN, Maduwanthi SDT, Marapana RAUJ (2019) Nutritional and health benefits of jackfruit (Artocarpus heterophyllus Lam.): A review. International J Food Sci 4327183. doi: https://doi.org/10.1155/2019/4327183
Rao AG, Naik KS, Unnikrishnan AG, Joseph J (2021) Efficacy of green jackfruit flour as a medical therapy replacing rice or wheat in patients with type 2 diabetes mellitus: a randaomized, double-blind, placebo-controlled study. Nutri Diabetes 11(18). doi: https://doi.org/10.1038/s41387-021-00161-4
Raphaelli CO, Dannenberg G, Dalmazo GO, Pereira ES, Radunz M, Vizzotto M, Fiorentini AM, Gandra EA, Nora L (2019) Antibacterial and antioxidant properties of phenolic-rich extracts from apple (Malus domestica cv. Gala). Inter Food Res J 26(4):1133
Riaz S, Hussain I, Ibrahim M, Ishtiaq M, Ali Q, Ali MM, Akash, MSH (2022) Extraction and optimization of active metabolites from cluster bean: An In vitro biological and phytochemical investigation. Dose-Response 20(2): 15593258221098992
Ribeiro SMR, Scheiber A (2010) Bioactive compounds in mango (Mangifera indica L.). In: Watson RR, Preedy VR (eds). Bioactive foods in promoting health: Fruits and Vegetables, Academic Imprint, 737p
Riya MP, Antu KA, Vinu T, Chandrakanth KC, Anilkumar KS, Raghu KG (2013) An in vitro study reveals nutraceutical properties of Ananas comosus (L.) Merr. Var. Mauritious fruit residue beneficial to diabetes. J Sci Food Agric 94(5):943-950. doi: 10.1002/jsfa.6340
Rose K, Wan C, Thomas A, Seeram NP, Ma H (2018) Phenolic compounds isolated and identified from amla (Phyllanthus emblica) juice powder and their antioxidant and neuroprotective activities. Natural Product Commun 13(10): 1309-1311
Saleem MTS, Madhusudana C, Ramkanth S, Rajan VST, Mahesh K, Gauthaman K (2010) Hepatoprotective herbs- a review. Inter J Res Pharma Sci 1(1): 1-5
Sánchez-Machado DI, Núñez-Gastélum JA, Reyes-Moreno C, Ramírez-Wong B, López-Cervantes J, (2010) Nutritional quality of edible parts of Moringa oleifera. Food analytical methods 3: 175-180
Santana LF, Inada AC, Santo BLSE, Filiu WFO, Pott A, Alves FM, Guimaraes RCA, Freitas KC, Hiane PA (2019) Nutraceutical potential of Carica papaya in metabolic syndrome. Nutrients 11(7): 1608. doi: https://doi.org/10.3390/nu11071608
Sarma A, Kashyap D, Sarmah P, Sultana S (2015) Evaluation of antioxidant activity and nutraceutical property of Annona squamosa L. fruits found in Brahmaputra valley agro-climatic condition. World J Pharmacy Pharma Sci 4(5): 1151-1157
Scartezzini F, Antognoni F, Raggi MA, Poli F, Sabbioni C (2005) Vitamin C content and antioxidant activity of the fruit and of the Ayurvedic preparation of Emblica officinalis Gaertn. J Ethnopharmacol 104: 113-118
Seal T, Pillai B, Chaudhuri K (2017) Evaluation of nutritional potential of five unexplored wild edible plants consumed by the tribal people of Arunachal Pradesh state in India. J Food Nutri Res 5(1): 1-5
Seong GU, Hwang IW, Chung SK (2016) Antioxidant capacities and polyphenolics of Chinese cabbage (Brassica rapa L. ssp. Pekinensis) leaves. Food Chem 199: 612-618
Shamina A, Karunakaran G, Tripathi PC, Shivashankara KS (2016) Evaluation of antioxidant activity, total phenolics and phytochemical content of selected varieties of karonda fruits (Carissa carandas). Indian J Agric Sci 86(6): 815–822
Sharma H, Chawla N, Dhatt AS (2019) Nutraceutical content and free radical scavenging capacity of brinjal (Solanum melongena L.) genotypes. Scientia horticulturae 244: 294-303
Shi M, Loftus H, McAinch AJ, Su XQ (2017) Blueberry as a source of bioactive compounds for the treatment of obesity, type 2 diabetes and chronic inflammation. J Func Foods 30: 16-29
Shi P, Chen J, Ge W, Liu Z, Han N, Yin J (2023) Antichilblain components in eggplant based on network pharmacology and biological evaluation. J Agric Food Chem 71(30): 11442-11453
Singh S, Devi MB (2015) Vegetables as a potential source of nutraceuticals and phytochemicals: A review. Inter J Med Pharma Sci 5(2): 1-14
Sipahi H, Orak D, Reis R, Yalman K, Senol O, Palabiyik-Yucelik SS, Deniz I, Algul D, Guzelmeric E, Celep ME, et al. (2022) A comprehensive study to evaluate the wound healing potential of okra (Abelmoschus esculentus) fruit. J Ethnopharmacol 287: 114843
Somawathi KM, Rizliya V, Wijesinghe DGNG, Madhujith WMT (2014) Antioxidant activity and total phenolic content of different skin coloured brinjal (Solanum melongena). Tropical Agric Res 26(1): 152-161
Somawathi KM, Rizliya V, Wickramasinghe HAM, Madhujith WMT (2016) A comparative study on antioxidant and DNA protective activity ofdifferent skin coloured brinjal (Solanum melongena). Procedia Food Sci 6: 117-122
Svobodova B, Barros L, Calhelha RC, Heleno S, Alves MJ, Walcott S, Bittova M, Kuban V, Ferreir IC (2017) Bioactive properties and phenolic profile of Momordica charantia L. medicinal plant growing wild in Trinidad and Tobago. Industrial crops products 95: 365-373
Tan YF, Li HL, Lai WY, Zhang JQ (2013) Crude dietary polysaccharide fraction isolated from jackfruit enhances immune system activity in mice. J Medicinal Food 16(7): 663-668. doi: 10.1089/jmf.2012.2565
Tomasz S, Natalia B, Wieslaw W (2016) Betalain profile, content and antioxidant capacity of red beetroot dependant on the genotype and root part. J Functional Foods 27: 249-261
Upadhyay R, Sehwag S, Singh SP (2016) Antioxidant activity and polyphenol content of Brassica oleracea varieties. Inter J Veg Sci 22(4): 353-363
Velderrain-Rodríguez GR, Quero J, Osada J, Martín-Belloso O, Rodríguez-Yoldi MJ (2021) Phenolic-rich extracts from avocado fruit residues as functional food ingredients with antioxidant and antiproliferative properties. Biomolecules 11(7): 977
Vinson JA, Hao Y, Su X, Zubik L (1998) Phenol antioxidant quantity and quality in foods: vegetables. J Agric Food Chem 46: 3630 - 3634
Vora D, Vora JD, Pednekar MSR, Khadke MRR (2017) Biochemical, Organoleptic and Antimicrobial Assessment of Asparagus (Asparagus Officinalis). J Biotechnol Biochem 3(2): 83-94
Wang RF, Xie WD, Zhang Z, Xing DM, Ding Y, Wang W, Ma C, Du LJ (2004) Bioactive compounds from the seeds of Punica granatum (pomegranate). J Natural Products 67: 2096-2098
Wang RF, Xiang L, Du LJ, Wang W (2006) The constituents of Punica granatum. Asia-Pacific Trad Med 3:61-70
Wang R, Ding Y Liu R, Xiang L, Du L (2010) Pomegranate: Constituents, bioactivities and pharmacokinetics. Fruit Veg Cereal Sci Biotechnol 4(2):77-87
WHO [World Health Organisation] (2022) Global health expenditure database. Available: https://apps.who.int/nha/database Accessed 22 Jan 2024
Wilson EA, Demmig-Adams B (2007) Antioxidant, anti-inflammatory and antimicrobial properties of garlic and onions. Nutri Food Sci 37(3): 178-183. doi: https://doi.org/10.1108/00346650710749071
Xia F, Zhong Y, Li M, Chang Q, Liao Y, Liu X, Pan R (2015) Antioxidant and anti-fatigue constituents of okra. Nutrients 7(10):8846-8858
Yang X, Yang S, Guo Y, Jiao Y, Zhao Y (2013) Compositional characterisation of soluble apple polysaccharides, and their antioxidant and hepatoprotective effects on acute CCl4-caused liver damage in mice. Food Chem 138(2-3):1256-1264
Yesodharan K, Sujana KA (2007) Wild edible plants traditionally used by the tribes in the Parambikulam Wildlife Sanctuary, Kerala, India. Natural Prod Radiance 6(1):74-80
Yokozawa T, Kim HY, Kim HJ, Okubo T, Chu DC, Juneja LR (2007) Amla (Emblica officinalis Gaertn.) prevents dyslipidaemia and oxidative stress in the ageing process. Braz J Nutr 97(6):1187–1195
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