Sepsis: early detection, laboratory investigations, nursing interventions, and documentation process
Keywords:
Sepsis, Neonatal Sepsis, Blood Cultures, Biomarkers, Molecular Diagnostics, Nursing Interventions, Documentation, Antibiotic Resistance, Early DetectionAbstract
Background: Sepsis is a life-threatening condition resulting from infection, with significant mortality and morbidity, particularly in neonates. The diagnosis of neonatal sepsis is challenging, as clinical signs often overlap with other life-threatening conditions, and blood culture methods have low sensitivity, especially in neonates. Sepsis is associated with significant healthcare costs, and rapid, accurate diagnosis is crucial to improving patient outcomes. Aim: This article aims to explore the early detection, laboratory investigations, nursing interventions, and documentation processes for neonatal sepsis, with a focus on identifying gaps and proposing improvements to enhance clinical outcomes. Methods: A comprehensive review of current diagnostic methods for neonatal sepsis, including blood cultures, biomarkers, and emerging diagnostic technologies, was conducted. The analysis includes the limitations of conventional diagnostic approaches, the role of nursing interventions in early detection, and the importance of accurate documentation in the management of neonatal sepsis. Results: Traditional blood culture methods are limited by slow results, low sensitivity, and the emergence of antibiotic-resistant organisms. Biomarkers like C-reactive protein (CRP) and procalcitonin (PCT) show promise but lack sufficient accuracy for early sepsis detection. Recent advances in molecular diagnostic technologies may significantly reduce diagnostic delays and improve pathogen identification, allowing for more targeted antibiotic treatment.
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