Effectiveness of educational programs on the Confusion Assessment Method for the ICU (CAM-ICU) in enhancing ICU delirium knowledge and skills among nurses
A systematic review
Keywords:
CAM-ICU, delirium, intensive care unit, nurse educationAbstract
Background: ICU delirium is underrecognized despite its high prevalence and adverse outcomes. The Confusion Assessment Method for the ICU (CAM-ICU) is a validated screening tool, but its use by nurses is inconsistent. Objective: To systematically review evidence on the effectiveness of educational programs teaching CAM-ICU in enhancing ICU nurses’ knowledge, skills, confidence, and adherence to delirium screening. Methods: Searches were conducted in PubMed, Scopus, CINAHL, Web of Science, and Google Scholar for studies from 2019–August 2025. Eligible studies involved ICU nurses, provided an educational intervention on CAM-ICU, and assessed knowledge, skills/accuracy, self-efficacy, or screening adherence. PRISMA guidelines were followed. Results: Twelve studies (1 RCT, 8 quasi-experimental, 3 QI initiatives) met inclusion. Across designs, educational programs improved delirium knowledge, assessment accuracy, self-confidence, and adherence to CAM-ICU documentation. Multimodal interventions (lectures, case-based learning, simulation, competency checks, and audit-feedback) were associated with the most sustained improvements. Conclusions: CAM-ICU–focused nurse education consistently enhances knowledge, skills, and adherence. Implementation into standard orientation, competency-based assessments, and delirium bundles is recommended.
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References
Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE Jr, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA. 2004;291(14):1753-62. DOI: https://doi.org/10.1001/jama.291.14.1753
Girard TD, Jackson JC, Pandharipande PP, Pun BT, Thompson JL, Shintani AK, et al. Delirium as a predictor of long-term cognitive impairment in survivors of critical illness. Crit Care Med. 2010;38(7):1513-20. DOI: https://doi.org/10.1097/CCM.0b013e3181e47be1
Salluh JIF, Wang H, Schneider EB, Nagaraja N, Yenokyan G, Damluji A, et al. Outcome of delirium in critically ill patients: systematic review and meta-analysis. BMJ. 2015;350:h2538. DOI: https://doi.org/10.1136/bmj.h2538
Devlin JW, Fong JJ, Fraser GL, Riker RR. Delirium assessment in the critically ill: Show me the data! Crit Care Clin. 2008;24(1):225-43.
Ely EW, Margolin R, Francis J, May L, Truman B, Dittus R, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med. 2001;29(7):1370-9 DOI: https://doi.org/10.1097/00003246-200107000-00012
Pun BT, Balas MC, Barnes-Daily DK, Thompson JL, Aldrich JM, Barr J, et al. Caring for critically ill patients with the ABCDEF bundle: results of the ICU Liberation Collaborative in over 15,000 adults. Crit Care Med. 2019;47(1):3-14.
Patel RP, Gambrell M, Speroff T, Scott TA, Pun BT, Okahashi J, et al. Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals. Crit Care Med. 2009;37(3):825-32. DOI: https://doi.org/10.1097/CCM.0b013e31819b8608
United Nations. Sustainable Development Goal 3: Ensure healthy lives and promote well-being for all at all ages. United Nations; 2015. Available from: https://sdgs.un.org/goals/goal3
Ministry of Health and Family Welfare, Government of India. National Health Policy 2017. New Delhi: MoHFW; 2017.
Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med. 2009;6(7):e1000097. DOI: https://doi.org/10.1371/journal.pmed.1000097
Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3. Cochrane; 2022.
Higgins JP, Altman DG, Gotzsche PC, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. DOI: https://doi.org/10.1136/bmj.d5928
Joanna Briggs Institute. Critical Appraisal Tools. Joanna Briggs Institute, University of Adelaide; 2022. Available from: https://jbi.global/critical-appraisal-tools.
Popay J, Roberts H, Sowden A, et al. Guidance on the Conduct of Narrative Synthesis in Systematic Reviews. A Product from the ESRC Methods Programme. Lancaster University; 2006.
Girard TD, Pandharipande PP, Ely EW. Delirium in the intensive care unit. Crit Care. 2018;22(1):60.
Gusmao-Flores D, Figueira Salluh JI, Chalhub RÁ, Quarantini LC. The Confusion Assessment Method for the ICU (CAM-ICU) and Intensive Care Delirium Screening Checklist (ICDSC): a systematic review and meta-analysis. Crit Care. 2012;16(4):R115. DOI: https://doi.org/10.1186/cc11407
Pun BT, Balas MC, Barnes-Daly MA, et al. Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. Crit Care Med. 2019;47(1):3–14. DOI: https://doi.org/10.1097/CCM.0000000000003482
Ramadan FH, Mohamed SM, Abou Zeina HA, Abed El-Ghany MH. Effect of educational training about CAM-ICU on nurses’ knowledge and practice regarding delirium assessment among critically ill patients. Egypt J Health Care. 2021;12(3):1350-64.
Elshamy K, Mohamed HE, Khalil NS. Effectiveness of an educational program on nurses’ knowledge, confidence, and practice regarding delirium assessment in intensive care units. BMC Nurs. 2025;24(1):47. doi:10.1186/s12912-025-03395-0 DOI: https://doi.org/10.1186/s12912-025-03395-0
Ely EW, Margolin R, Vasilevskis EE, Pun BT, Bernard GR, Dittus RS, et al. Improving delirium detection in the intensive care unit through a multicenter “Train-the-Trainer” and tele-delirium program. Crit Care Med. 2021;49(9):e857-65. doi:10.1097/CCM.0000000000005070 DOI: https://doi.org/10.1097/CCM.0000000000005070
Devlin JW, Fong JJ, Fraser GL, Riker RR. Delirium assessment in the critically ill: Show me the data! Crit Care Clin. 2008;24(1):225-43. doi:10.1016/j.ccc.2007.11.004 DOI: https://doi.org/10.1016/j.ccc.2007.11.004
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