Attention deficit hyperactivity disorder’s incidence in children and adolescents worldwide: A comprehensive review of meta-analyses

https://doi.org/10.53730/ijhs.v9nS1.14509

Authors

  • Harjinder SGT University, Gurugram, Haryana, India
  • Sarika Yadav SGT University, Gurugram, Haryana, India
  • Khushbu SGT University, Gurugram, Haryana, India

Keywords:

Children, Adolescents, Umbrella review, Meta-analysis, ADHD

Abstract

Background: According to newly available epidemiological data, hundreds of primary research as well as dozens of systematic evaluations and meta-analyses have looked into the prevalence of ADHD in kids and teenagers. A thorough synthesis of the data from these systematic reviews and meta-analyses is what this umbrella review aims to provide. Objective: To comprehensively synthesize and evaluate existing evidence from systematic reviews and meta-analyses on the global prevalence of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents, using an umbrella review approach. Methods: We conducted a thorough search of PubMed, Web of Science, PsychINFO, and Scopus to locate relevant research. PROSPERO had the study preregistered. Using a Measurement Tool to Assess Systematic Reviews (AMSTAR), the studies' quality was evaluated. Using an invariance variance weighted random-effect meta-analysis, the prevalence estimates from the included studies were combined. Result: 3,277,590 participants from 13 meta-analytic systematic reviews (588 primary investigations) were analyzed. The worldwide prevalence of ADHD in children and adolescents was 8.0% (95% CI 6.0–10%). Boys had a prevalence estimate twice as high (10%) as girls (5%). The inattentive type (ADHD-I) was the most prevalent subtype. 

Downloads

Download data is not yet available.

References

Alvidrez J. Ethnic variations in mental health attitudes and service use among low-income African American, Latina, and European American young women. Community Ment Health J. 1999;35(6):515–30. DOI: https://doi.org/10.1023/A:1018759201290

Ayano G, Maravilla JC, Alati R. Risk of autistic spectrum disorder in offspring with parental mood disorders: a systematic review and meta-analysis. J Affect Disord. 2019;248:185–97. DOI: https://doi.org/10.1016/j.jad.2019.01.038

Ayano G, Tesfaw G, Shumet S. The prevalence of schizophrenia and other psychotic disorders among homeless people: a systematic review and meta-analysis. BMC Psychiatry. 2019;19(1):370. DOI: https://doi.org/10.1186/s12888-019-2361-7

Ayano G, Yohannes K, Abraha M. Epidemiology of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents in Africa: a systematic review and meta-analysis. Ann Gen Psychiatry. 2020;19:21. DOI: https://doi.org/10.1186/s12991-020-00271-w

Ayano G, Betts K, Tait R, Dachew BA, Alati R. Maternal depressive and anxiety symptoms and the risk of attention deficit hyperactivity disorder symptoms in offspring aged 17: findings from the Raine study. J Affect Disord. 2021;284:149–56. DOI: https://doi.org/10.1016/j.jad.2021.02.024

Ayano G, Lin A, Dachew BA, Tait R, Betts K, Alati R. The impact of parental mental health problems on the educational outcomes of their offspring: findings from the Raine study. Aust N Z J Psychiatry. 2022;56(5):510–24. DOI: https://doi.org/10.1177/00048674211025633

Ayano G, Betts K, Dachew BA, Alati R. Academic performance in adolescent offspring of mothers with prenatal and perinatal psychiatric hospitalizations: a register-based, data linkage, cohort study. Psychiatry Res. 2023;319:114946. DOI: https://doi.org/10.1016/j.psychres.2022.114946

Berger I. Diagnosis of attention deficit hyperactivity disorder: much ado about something. Isr Med Assoc J. 2011;13(9):571.

Berry CA, Shaywitz SE, Shaywitz BA. Girls with attention deficit disorder: a silent minority? A report on behavioral and cognitive characteristics. Pediatrics. 1985;76(5):801–9. DOI: https://doi.org/10.1542/peds.76.5.801

Borenstein M, Hedges LV, Higgins J, Rothstein HR. A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Synth Methods. 2010;1(2):97–111. DOI: https://doi.org/10.1002/jrsm.12

Catalá-López F, Peiró S, Ridao M, Sanfélix-Gimeno G, Gènova-Maleras R, Catalá MA. Prevalence of attention deficit hyperactivity disorder among children and adolescents in Spain: a systematic review and meta-analysis of epidemiological studies. BMC Psychiatry. 2012;12:168. DOI: https://doi.org/10.1186/1471-244X-12-168

Cénat JM, Blais-Rochette C, Morse C, Vandette MP, Noorishad PG, Kogan C, et al. Prevalence and risk factors associated with attention-deficit/hyperactivity disorder among US black individuals: a systematic review and meta-analysis. JAMA Psychiatry. 2021;78(1):21–8. DOI: https://doi.org/10.1001/jamapsychiatry.2020.2788

Cénat JM, Kokou-Kpolou CK, Blais-Rochette C, Morse C, Vandette MP, Dalexis RD, et al. Prevalence of ADHD among Black youth compared to White, Latino and Asian youth: a meta-analysis. J Clin Child Adolesc Psychol. 2022:1–16. DOI: https://doi.org/10.1080/15374416.2022.2051524

Chan E, Zhan C, Homer CJ. Health care use and costs for children with attention-deficit/hyperactivity disorder: national estimates from the medical expenditure panel survey. Arch Pediatr Adolesc Med. 2002;156(5):504–11. DOI: https://doi.org/10.1001/archpedi.156.5.504

Chan MF, Al Balushi R, Al Falahi M, Mahadevan S, Al Saadoon M, Al-Adawi S. Child and adolescent mental health disorders in the GCC: a systematic review and meta-analysis. Int J Pediatr Adolesc Med. 2021;8(3):134–45. DOI: https://doi.org/10.1016/j.ijpam.2021.04.002

Chauhan A, Sahu JK, Singh M, Jaiswal N, Agarwal A, Bhanudeep S, et al. Burden of attention deficit hyperactivity disorder (ADHD) in Indian children: a systematic review and meta-analysis. Indian J Pediatr. 2022;89(6):570–8. DOI: https://doi.org/10.1007/s12098-021-03999-9

Chesney E, Goodwin GM, Fazel S. Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry. 2014;13(2):153–60. DOI: https://doi.org/10.1002/wps.20128

Cortese S, Kelly C, Chabernaud C, Proal E, Di Martino A, Milham MP, Castellanos FX. Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studies. Am J Psychiatry. 2012;169(10):1038–55. DOI: https://doi.org/10.1176/appi.ajp.2012.11101521

Doshi JA, Hodgkins P, Kahle J, Sikirica V, Cangelosi MJ, Setyawan J, et al. Economic impact of childhood and adult attention-deficit/hyperactivity disorder in the United States. J Am Acad Child Adolesc Psychiatry. 2012;51(10):990–1002.e2. DOI: https://doi.org/10.1016/j.jaac.2012.07.008

Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–34. DOI: https://doi.org/10.1136/bmj.315.7109.629

Meng L, Chen Y, Xu X, Chen T, Lui S, Huang X, et al. The neurobiology of brain recovery from traumatic stress: a longitudinal DTI study. J Affect Disord. 2018;225:577–84. DOI: https://doi.org/10.1016/j.jad.2017.08.075

Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097. DOI: https://doi.org/10.1371/journal.pmed.1000097

Montano B. Diagnosis and treatment of ADHD in adults in primary care. J Clin Psychiatry. 2004;65(Suppl 3):18–21.

Pang X, Wang H, Dill SE, Boswell M, Pang X, Singh M, et al. Attention Deficit Hyperactivity Disorder (ADHD) among elementary students in rural China: prevalence, correlates, and consequences. J Affect Disord. 2021;293:484–91. DOI: https://doi.org/10.1016/j.jad.2021.06.014

Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry. 2007;164(6):942–8. DOI: https://doi.org/10.1176/ajp.2007.164.6.942

Polanczyk GV, Salum GA, Sugaya LS, Caye A, Rohde LA. Annual research review: a meta-analysis of the worldwide prevalence of mental disorders in children and adolescents. J Child Psychol Psychiatry. 2015;56(3):345–65. DOI: https://doi.org/10.1111/jcpp.12381

Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007;7:10. DOI: https://doi.org/10.1186/1471-2288-7-10

Slim K, Marquillier T. Umbrella reviews: a new tool to synthesize scientific evidence in surgery. J Visc Surg. 2022;159(2):144–9. DOI: https://doi.org/10.1016/j.jviscsurg.2021.10.001

Thomas R, Sanders S, Doust J, Beller E, Glasziou P. Prevalence of attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Pediatrics. 2015;135(4):e994–1001. DOI: https://doi.org/10.1542/peds.2014-3482

Vasileva M, Graf RK, Reinelt T, Petermann U, Petermann F. Research review: a meta-analysis of the international prevalence and comorbidity of mental disorders in children between 1 and 7 years. J Child Psychol Psychiatry Allied Discip. 2021;62(4):372–81. DOI: https://doi.org/10.1111/jcpp.13261

Wang T, Liu K, Li Z, Xu Y, Liu Y, Shi W, et al. Prevalence of attention deficit/hyperactivity disorder among children and adolescents in China: a systematic review and meta-analysis. BMC Psychiatry. 2017;17(1):32. DOI: https://doi.org/10.1186/s12888-016-1187-9

Wei M, Heppner PP, Ku TY, Liao KYH. Racial discrimination stress, coping, and depressive symptoms among Asian Americans: a moderation analysis. Asian Am J Psychol. 2010;1(2):136. DOI: https://doi.org/10.1037/a0020157

Weyandt LL, Iwaszuk W, Fulton K, Ollerton M, Beatty N, Fouts H, et al. The internal restlessness scale: performance of college students with and without ADHD. J Learn Disabil. 2003;36(4):382–9. DOI: https://doi.org/10.1177/00222194030360040801

Willcutt E. The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review. Neurotherapeutics. 2012;9(3):490–9. DOI: https://doi.org/10.1007/s13311-012-0135-8

Yadegari N, Sayehmiri K, Azodi MZ, Sayehmiri F, Modara F. The prevalence of attention deficient hyperactivity disorder among Iranian children: a meta-analysis. Iran J Psychiatry Behav Sci. 2018;12(4). DOI: https://doi.org/10.5812/ijpbs.8990

Zhao X, Page TF, Altszuler AR, Pelham WE 3rd, Kipp H, Gnagy EM, et al. Family burden of raising a child with ADHD. J Abnorm Child Psychol. 2019;47(8):1327–38. DOI: https://doi.org/10.1007/s10802-019-00518-5

Published

20-07-2025

How to Cite

Harjinder, H., Yadav, S., & Khushbu, K. (2025). Attention deficit hyperactivity disorder’s incidence in children and adolescents worldwide: A comprehensive review of meta-analyses. International Journal of Health Sciences, 9(S1), 378–389. https://doi.org/10.53730/ijhs.v9nS1.14509

Issue

Section

Peer Review Articles

Most read articles by the same author(s)