High C-reactive protein/albumin ratio increased risk of acute malnutrition during hospitalization in pediatric patients

  • I Gusti Lanang Sidiartha Department of Child Health, Medical Faculty, Udayana University, Denpasar, Indonesia
  • Dyah Kanya Wati Department of Child Health, Medical Faculty, Udayana University, Denpasar, Indonesia
  • Ida Bagus Subanada Department of Child Health, Medical Faculty, Udayana University, Denpasar, Indonesia
  • I Gusti Ngurah Made Suwarba Department of Child Health, Medical Faculty, Udayana University, Denpasar, Indonesia
Keywords: albumin, CRP, inflammation, malnutrition, pediatric

Abstract

Pediatric patients with malnutrition commonly have poor prognosis related to the inflammation and catabolism state. This study investigated the relationship between high C-Reactive Protein/Albumin ratio on admission with the risk of acute malnutrition during hospitalization in pediatric patients. A cohort study in patients aged 1 month to 18 years old who met the study criteria was done. On admission, the level of serum C-Reactive Protein and Albumin were measured and calculated the C-Reactive protein/Albumin ratio which was divided into the high and low ratio. Acute malnutrition was determined according to the weight-for-height or body mass index-for-age z-score less than 2 SD below the WHO Child Growth Standard median.  A total of 110 patients were analyzed, 50% male and the mean aged was 77.7 months. Patients with acute malnutrition on admission and discharge were 24.5% and 32.7%, respectively. Acute malnutrition on discharge in patients with high and low ratio were 51.6% and 25.3%, respectively (adjusted Relative Risk, 9.1; 95% CI: 1. 9 to 42.7; p = 0.005). High C-Reactive Protein/Albumin ratio on admission increased the risk of acute malnutrition during hospitalization in pediatric patients.

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Published
2020-10-12
How to Cite
Sidiartha, I. G. L., Wati, D. K., Subanada, I. B., & Suwarba, I. G. N. M. (2020). High C-reactive protein/albumin ratio increased risk of acute malnutrition during hospitalization in pediatric patients. International Journal of Health Sciences, 4(3), 32-38. https://doi.org/10.29332/ijhs.v4n3.453
Section
Research Articles