Morinda citrifolia mediated biogenic synthesis of selenium nanoparticles and evaluation of its antimicrobial and antioxidant activity

https://doi.org/10.53730/ijhs.v6nS1.5312

Authors

  • Lalitha Rani Chellappa Senior Lecturer, Department of Public Health Dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai
  • Srisakthi Doraikannan Reader, Department of Public Health Dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai

Keywords:

noni fruit extract (NFE), selenium nanoparticles, green synthesis, antimicrobial activity, antioxidant, local drug delivery

Abstract

Purpose : The aim of the study is to assess its potential to synthesize selenium nanoparticles (SeNPs) with Noni fruit extract and augment its antimicrobial and antioxidant activity. Materials and methods: The synthesized SeNPs were confirmed using UV-vis spectroscopy and transmission electron microscopy (TEM). Antimicrobial activity against S. mutans, S. aureus, E. faecalis, C. albicans was tested using agar diffusion; antioxidant potential assessed on 2,2-diphenyl-2-picrylhydrazyl hydrate oxidation. Results : UV-vis, and TEM confirmed the synthesis of SeNPs and revealed smooth spherical nanoparticles (25-100nm). SeNPs exhibited significant antimicrobial activity for the provided concentration against all organisms and excellent antioxidant potential in a dose dependent manner (84% inhibition/50 µl concentration). Conclusion : Morinda citrifolia augmented biogenic SeNPs is a cost effective yet efficient method and they show great potential as oral antimicrobial agent with superior antioxidant properties and is eco-friendly.

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Published

31-03-2022

How to Cite

Chellappa, L. R., & Doraikannan, S. (2022). Morinda citrifolia mediated biogenic synthesis of selenium nanoparticles and evaluation of its antimicrobial and antioxidant activity. International Journal of Health Sciences, 6(S1), 2475–2486. https://doi.org/10.53730/ijhs.v6nS1.5312

Issue

Section

Peer Review Articles