An imperical analysis of various extracts of Bacopa Monnieri towards antibacterial and antifungal activities

Amrita Indoliya; Hari Om Nagar; S. K. Singh

doi:10.53730/ijhs.v6nS3.6251

Authors

Amrita Indoliya
amrita26indoliya@gmail.com
Research Scholar, Department of Chemistry, Suresh Gyan Vihar University, Jaipur
Hari Om Nagar Professor , Department of Chemistry ,Suresh Gyan Vihar University, Jaipur
S. K. Singh Principal & Professor , Department of Pharmacy ,Suresh Gyan Vihar University, Jaipur

Keywords:

antibacterial, antifungal, bacopa monnieri, medicinal plants, India

Abstract

Bacopa monnieri was also known as “Brahmi.” Theses plant has been considered as medicinal plants in Ayurvedic systems for centuries. This present study was carried out to evaluate the antibacterial and antifungal properties of ethanolic, diethyl ether, ethyl acetate, and aqueous extracts of B. monnieri. Agar disc diffusion tests were carried out to determine the antimicrobial effects of ethanolic, diethyl ether, ethyl acetate and aqueous extracts of B. monnieri against Gram-positive (Staphylococcus aureus), Gram-negative (Escherichia coli) bacterial strains and antifungal strains (Aspergillus flavus, and Candida albicans). Among the various extracts, diethyl ether extracts of B. monnieri has an antibacterial potency against Staphylococcus aureus (gram positive), and ethyl acetate extract showed effects on E. coli (gram negative) at higher concentrations of 300 μg mL-1. The ethanolic extract has potent antifungal activity against the fungus (Aspergillus flavus, and Candida albicans) compared to diethyl ether and ethyl acetate-ether. Both extracts (diethyl ether and ethyl acetate) has a minimum antifungal effect while these extracts showed more inhibitory effects on tested bacteria.

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