Relationship of fibroblast growth factor 23 (FGF23) to antioxidants and lipid level in patients with kidney diseases

Hend M. Ahmed; Nawal Th. Younis

doi:10.53730/ijhs.v6nS2.6300

Authors

Hend M. Ahmed Department of chemistry, Collage of Education for Pure Sciences, University of Mosul, Mosul, Iraq
Nawal Th. Younis
dr.nawal.thanoon@uomosul.edu.iq
Department of chemistry, Collage of Education for Girls, University of Mosul, Mosul, Iraq

Keywords:

FGF23, dyslipidemia, antioxidant, BMI, CKD

Abstract

The research involved study the relation between FGF23 and some of the biochemical parameters related to the chronic kidney disease (Glutathion GSH and arylesterase ARE enzymes,ceruloplasmin ,Malondialehyde ,glucose ,cholesterol ,triglyceride ,LDL ,VLDL,HDL)in serum blood patients compared with control group,the result demonstration is a significant increase in the mean concentration rate FGF23 was (324.06± 291.1 pg/ml) in patients compared with mean concentration in control group was ( 273 ± 188.5 pg/ml) , also the result showed a significant increase in the concentration of (ceruloplasmin,malondialdehyde ,cholesterol ,LDL) and a significant decrease had been shown in the concentration of (reduced Glutathion,arylesterase,HDL).while the results had been showed a non significant increase with (glucose,triglyceride,VLDL) in patients compared with control group, Correlation coefficient of FGF23 with these clinical parameters showed a positive significant correlation with(Malondialdehyde) while the result showed a non significant correlation with rest of the biochemical parameters.

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