Blood donors
The life saviour, as per Kuppuswamy’s socio economic scale –who are safest?
Keywords:
Replacement donors, Voluntary donors, TTI- Transfusion Transmitted InfectionsAbstract
Evaluation of TTI (transfusion transmitted infections) are essential for assessing the safety of blood supply and monitoring the efficacy of currently employed screening procedures. Objective: To assess the prevalence of HBV, HCV and HIV among replacement donors and voluntary donor in association with the Kuppuswamy’s socioeconomic status. Material and Methods: A retrospective analysis of total 10569 blood donors from Jan2014 to Sep 2015 was conducted at a blood bank in a tertiary care hospital in North India, Teerthanker Mahaveer Medcial college and research centre. Donor with hemoglobin (Hb) less than 12.5gm% or known seropositive for TTI were deferred and excluded from the study group. The hemoglobin level was measured by copper sulphate method, samples were screened for: a) HIV-1 and p antigen ELISA kits from Mitra& Co. ltd , for anti HIV I and II 4th generation Microlisa- HIV Ag and Ab. b) HBsAg- Hepalisac) anti HCV d) Malaria Age) Syphilis. Observation: The prevalence of HBV and HCV was noted to be higher among replacement donors as compared to voluntary donors, while in HIV, the prevalence was noted only in voluntary donors. Total 10,569 blood donors were grouped as per the KSESS, maximum donors in lower middle class III-5789.
Downloads
References
Zaller N, Nelson K.E., Ness P , Wen ZG., Bai X., Shan H., Knowledge, attitude and practice survey regarding blood donation in a northwestern Chinese city. Transfusion Medicine . 2005; 15(4);277- 286.doi: 10.1111/j.0958- 7578.2005.00589.x. [Pubmed][cross ref].
CaspariG. ,Gerlich W.H., Gurtler L. Paying for blood donation-still a risk? Vox Sanguinis.2003;85(1);52.doi:10.1046/j.142 3-0410.2003.00321.x.[Pubmed][crossref]
Dhingra N. Blood safety in the developing world and WHO initiatives. Vox sanguinis.2002;83(supplement 1);173- 177.doi: 10.1111/j.1423- 0140.2002.tb05295.x. [Pubmed] [crossref.]
Nagalo MB, Sanou M, Bisseye C, Kabore MI, Nebie YK, KienouK,et al. Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses and syphilis among blood donors in Kaudougou(Burkina Faso) in 2009. Blood transfuse.2011;9:419-24[PMC free article] [pubmed]
Pallavi P, Ganesh CK, Jayashree K, Manjunathy GV. Seroprevalence and trends in transfusion transmitted infection among blood donors in a university hospital blood bank, A 5 yaer study. Indian J Hematol blood Transfus.2011;27:1- 6[PMC free article][Pubmed]
Jeremiah ZA,Koate B, Buseri F, Emelike F. prevalence of antibodies to hepatitis C virus in apparently healthy post Harcourt blood donors and association with blood groups and other risk indicators: Blood Transfus.2008;6:150-5.[PMC free article] [Pubmed]
Das BK,Gagan BK, ditya S, Chakrovorty SK, Datta PK, Joseph. seroprevalence of hepatitis B, hepatitis C, and human immunodeficiency virus among healthy voluntary first-time blood donors in kolkatta.Ann trop MedPublic Health [serial online] 2011[cited 2012 Jul 15];4:86-90.
Wienberger KM, Bauer T, Bohm S, Jilg W. High genetic variability of the group – specific adeterminant of Hepatitis B virus surface antigen (HBsAg) and the corresponding fragment of the viral polymerase in chronic virus carriers lacking detectable HBsAg in serum.J Gen Virol 2008;81:1165-74.
Wildmann FK editor. Technical Manual American association of blood banks.Aglington USA:1985,p325-44.
Cumming PD, Wallace EL, Schoor JB, Dodd RY. Exposure of patients to HIV through the transfusion of blood components that test antibody negative. N Engl J Med 1989;321:941-6
Shah N, Shah JM, Jhaveri P, Patel K, Shah CK, Shah NR. Seroprevalence of HBV, HCV, HIV and Syphillis among blood donors at a tertiary care teaching hospital in western India. Gujrat Med J 2013;68:35-9
Makroo RN, Salil P, Vashist RP, Shivlal. Trends of HIV infection in the blood donors of Delhi. Indian J Pathcol Microbiol 1996;39;139-42.
Aroar D, Aroar B, Khetarpal .Seroprevalance of HIV,HBV,HCV and Syphilis in blood donors in southern Haryana. Indian J Pathol Microbiol 2010;52:308-9.
Singh B, Verma M, Verma K, Markers for transfusion associated hepatitis in north Indian blood donors – Prevalence and trends. Jpn J Infect Dis 2004;57:49-51
Gupta N, Kumar V, Kaur a. seroprevalence of HIV, HBV,HCV and syphilis in voluntary blood donors. Indian J Med Sci 2004;58:255-7.
Lathamani K, Bhaktha G, Nayak S, Kotigadde S. Prevalence of HIV, HBV,HCV and syphilis in blood donors among the Dakshina Kannada District, India. Int J currMicrobiol App Sci 2013;2;249-52.
Garg S, Mathur DR, Garg DK. Comparison of seropositivity of HIV,HBV, HCVand syphilis in replacement and voluntary blood donors in western India. Indian J Pathol Microbiol 2001;44:409-12.
Towars 100% voluntary blood donation: A Global Framework for action. Available from: http:www.Who.Int/ blood safety/publications/9789241599696- evg.pdf.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
![Creative Commons License](http://i.creativecommons.org/l/by-nc-nd/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.