Evaluate the liver injury in COVID-19 patients at government medical college and hospital, Ambikapur
Keywords:
COVID-19, liver function test, AST, ALT, bilirubin, coronavirusAbstract
A pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or novel coronavirus disease (COVID-19) began in December 2019 in China's Wuhan region and spread worldwide by April 2020, affecting 187 of the world's 192 countries with varied degrees of severity. When alanine aminotransferase (ALT) was > 55 U/l or total bilirubin was > 1.6 mg/dl, a patient was regarded to have liver damage. For laboratory data, the Spearman correlation coefficient was calculated, and bivariable analysis for mortality and/or the need for intensive care was performed. Aim: To evaluate the liver injury in covid-19 patients at government medical college and hospital. Methods and Materials: All the Patients were admitted in Covid ward at Govt. medical college and hospital, Ambikapur, Chhattisgarh. India. Present study were divided into two groups. Group-I: Female COVID Positive Patients -20, Group-II –Male COVID positive Patients -20.Conclusion: To summarise, patients with COVID-19 in Ambikapur, Chattisgarh, had a significant rate of abnormal liver function tests, which was linked to poorer outcomes when they developed severe acute respiratory distress syndrome.
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References
WHO Director-General's opening remarks at the media briefing on COVID-19. (2020).
Velavan TP, Meyer CG: The COVID-19 epidemic . Trop Med Int Health. 2020, 25:278-280.10.1111/tmi.13383
WHO. Coronavirus disease 2019 (COVID-19): situation report, 73 . (2020).
WHO. Q&A on coronaviruses (COVID-19). (2020). http://www.emro.who.int/healthtopics/corona-virus/questions-and-answers.html.
Guan W-J, Ni Z-Y, Hu Y, et al.: Clinical characteristics of coronavirus disease 2019 in China . N Engl J Med. 2020, 328:1708-1720. 10.1056/NEJMoa2002032
Patel A, Charani E, Ariyanayagam D, Abdulaal A, Denny SJ, Mughal N, Moore LSP: New-onset anosmia and ageusia in adult patients diagnosed with SARS-CoV-2 infection. Clin Microbiol Infect. 2020, [Epub ahead of print]:10.1016/j.cmi.2020.05.026
Huang C, Wang Y, Li X, et al.: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020, 395:497-506.
Li LQ, Huang T, Wang YQ et al (2020) 2019 novel coronavirus patients’ clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol 92:577–583
Chen T, Wu D, Chen H et al (2020) Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ (Epub ahead of print)
Wang Z, Yang B, Li Q, Wen L, Zhang R (2020) Clinical features of 69 cases with coronavirus disease 2019 in Wuhan, China. ClinInfect Dis (Epub ahead of print)
Jia HP, Look DC, Shi L et al (2005) ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol79:14614–14621.
World Health Organization.Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected. January 28, 2020. Accessed 15 Aug 2021.
Lan L, Xu D, Ye G, Xia C, Wang S, Li Y, et al. Positive RT-PCR test results in patients recovered from COVID-19. JAMA. 2020;323(15):1502–3.
Villar J, Pérez-Méndez L, Blanco J et al (2013) A universal definition of ARDS: the PaO2/FiO2 ratio under a standard ventilator setting—a prospective, multicenter validation study. Intensive Care Med 39:583–592.
Zhang S, Hu B, Xu J, Ren Q, Wang L, Wang S (2019) Influenza A virus infection induces liver injury in mice. Microb Pathog 137:103736.
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395(10223):507–13.
Akilli NB, Yortanlı M, Mutlu H et al (2014) Prognostic importance of neutrophil-lymphocyte ratio in critically ill patients:short- and long-term outcomes. Am J Emerg Med 32:1476–1480.
Rosenbaum L (2020) Facing Covid-19 in Italy—ethics, logistics,and therapeutics on the epidemic’s front line. N Engl J Med 382:1873–1875.
Emanuel EJ, Persad G, Upshur R et al (2020) Fair allocation of scarce medical resources in the time of Covid-19. N Engl J Med 382:2049–2055.
Truog RD, Mitchell C, Daley GQ (2020) The toughest triage allocating ventilators in a pandemic. N Engl J Med 382:1973–1975.
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