An observational study to evaluate pressor response to laryngoscopy and tracheal intubation after pre-operative nebulisation of lignocaine

Anuja Agrawal; Ankitkumar Shah; Malini Mehta; Dinesh Chauhan

doi:10.53730/ijhs.v6nS2.7111

Authors

Anuja Agrawal Associate Professor, Emergency Medicine, Smt. Bhikhiben Kanjibhai Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth An Institution to be Deemed, Piparia, Vadodara, Gujarat, India-393760
Ankitkumar Shah 2nd Year Resident, Department of Anaesthesia, Smt. Bhikhiben Kanjibhai Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth An Institution to be Deemed, Piparia, Vadodara, Gujarat, India-393760
Malini Mehta
m_malini17@yahoo.in
Professor & Head of Department, Emergency Medicine, Smt. Bhikhiben Kanjibhai Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth An Institution to be Deemed, Piparia, Vadodara, Gujarat, India-393760
Dinesh Chauhan Professor & Head of Department, Anaesthesia, Smt. Bhikhiben Kanjibhai Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth An Institution to be Deemed, Piparia, Vadodara, Gujarat, India-393760

Keywords:

laryngoscopy, intubation, lignocaine, nebulization

Abstract

Background & Aims: - Direct laryngoscopy and intubation are essential steps in general anaesthesia which elicit significant adreno sympathetic responses. Suppression of these responses is a concern in general anaesthesia. The aim of our study is to evaluate haemodynamic effects of pre-operative nebulisation with lignocaine due to pressor response. Materials and Methods :- Fifty patients within the age group of 18-65 years undergoing elective surgery under general anaesthesia were randomly allocated into two groups: Group L (n=25) nebulised with 5 ml lignocaine (2%) and Group C (n=25) nebulised with 5 ml normal saline, 15 minutes before surgery. Baseline values of heart rate (HR), systolic blood pressure(SBP), diastolic blood pressure(DBP), mean arterial pressure(MAP) and saturation(SpO2) were noted. HR, SBP, DBP, MAP and SpO2 were noted immediately after intubation, at 2 minutes, 5 minutes and 10 minutes after intubation. Results:- There was significant fall in HR (88.76 ± 8.54) and MAP (93.32 ± 14.42) in group L as compared to group C. Conclusion:- This study suggests that pre-operative nebulisation with lignocaine significantly suppresses pressor response to laryngoscopy and intubation.

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