Molecular detection of GSTM1 and GSTT1 gene polymorphisms and their association with prostate cancer risk

Ali Jabbar Abdulla; Zainab Nizar Jawad

doi:10.53730/ijhs.v6nS3.7482

Authors

Ali Jabbar Abdulla
ali.jabbar@s.uokerbala.edu.iq
Department of Biology, College of Education for Pure Sciences, University of Kerbala, Kerbala, Iraq
Zainab Nizar Jawad Department of Biology, College of Education for Pure Sciences, University of Kerbala, Kerbala, Iraq

Keywords:

molecular detection, polymorphisms, association, prostate cancer risk

Abstract

The role of the current study in the detection of polymorphisms appears in genes GSTT1& GSTM1 polymorphisms ,They are genes that have polymorphisms and have an important role in the occurrence of diseases, especially cancers such as prostate cancer, and Samples for the study were collected from 50 patients with prostate cancer (from the patients of the Imam Al-Hussein Center - peace be upon him - for cancerous tumors and blood diseases at Al-Hussein Teaching Hospital, peace be upon him - Holy Karbala Governorate – Iraq) After diagnosis by the oncological surgeon and 50 samples collected from phenotypically healthy individuals as a control group the (DNA) was extracted from the blood of both patients group and healthy group. Molecular detection of the nucleotide polymorphism in the genes under our study was carried out using Multiplex- PCR .t

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