Effect of sesame oil on some blood parameters and antioxidants in ovariectomized female white rats
Keywords:
sesame oil, blood, antioxidants, ovariectomizedAbstract
This study was conducted to find out the physiological effect of sesame seed oil (Sesamum indicum) in the case of oral treatment on post-menopause and the occurrence of surgical menopause as a result of the removal of the ovaries, by studying the changes in some blood parameters and some antioxidants in the serum of adult female rat pupae. White (Albino Rats), 15 adult rats about three months old, with weights ranging between 160-180 g, were used. The animals were randomly divided into three groups, five animals per group. The first group represented the negative control, which was normal without removing the ovaries, the second represented the positive control in which the ovaries were completely removed, and the third group had the ovaries completely removed and treated orally with sesame oil at a concentration of 4 ml/kg of body weight per day for a period of 30 days.
Downloads
References
Surh, Y.J. (2003). Cancer chemoprevention with dietary phytochemicals Nat. Rev. Cancer, 3:768-780.
Jayaraj, Premkumar ; Aluganti, Chandrakala ; Rajagopalan, Sanjay ; Parthasarathy, Sampath and Desikan, Rajagopal (2020). Sesamol: A powerful functional food ingredient from sesame oil for cardioprotection. Food & Function. 11(2):1198-1210.
Morales, A. ; Vicente, C. ; Santiag, J. ; Egido, J. ; Mayoral, P. ; Arevalo, M. ; Fernandez, M. ; Lopez-Novoa, J. and Perez, F. (2006). Protective effect of quercetin on experimental chronic cadmium nephrotoxicity in rats is based on its antioxidant properties. Food and Chemical Toxicology. 44: 2092-2100.
Moazzami, A. and Kamal-Eldin, A. (2009). 8-Sesame seed oil. In: Moreau, R.A., Kamal- Eldin, A. (Eds.), Gourmet and Health-Promoting Specialty Oils. AOCS Press, pp. 267-282.
Bah kali, A. ; Hussain, M. and Basahy, A. (1998). Protein and oil composition of sesame seeds (Sesamum indicum, L.) grown in the Gizan area of Saudi Arabia. Inter. J. of Food Sci. and Nut., 49:409-414.
Morris, J.B. (2002). Food, Industrial, Nutraceutical, and pharmaceutical Uses of Sesame genetic resources. In J. Janick and A. Whipkey (eds). Trends in new Crops and new uses. ASHS Press, Alexandria,V.A.P:153-156.
Amoo, S.O., Okorogbona, A.O.M., Du Plooy, C.P., Venter, S.L., 2017. Sesamum indicum. In: Medicinal Spices and Vegetables from Africa. pp. 549-579.
Fuller, D.Q. (2003). Further evidence on the prehistory of sesame. Asian Agri-Hist. 7, 127-137.
AOAC (2005). Official methods of analysis (16th Ed.). Washington, DC: Association of Official Analytical Chemists.
Aref Salehzadeh ; Roghaye Abbasalipourkabir ; Behrooz Shisheian ; Ali Rafaat ; Ali Nikkhah and Tahereh Rezaii (2018). The alleviating effects of sesame oil on diazinon-induced toxicity in male wistar rats, Drug and Chemical Toxicology. DOI: 10.1080/01480545.2018.1449852.
Albozachri, J.M.K. ; Hameed, F.M. ; AL-Tomah, H.M. and Muhammid, H.A. (2017). Evaluation of tow general anesthetic regimeby use xylazine and ketamine with atropine and diazepam in rabbits . J. University of Kerbala, 15:21-30.
Parhizkar, S. ; Ibrahim, R. and Abdul Latiff, L. (2008). Incision choice in laparatomy :A comparison of two incision techniques in ovariectomy of rats .World Appl. Sci. J., 4(4):537-540.
AL-Zamely, O. M. Y. (2001). Ischemic Heart Disease Via Oxidative Hypothesis. (Thesis), PH. D., Iraq, University of AL-Mustansiriya.
Muslih, B. ; Mizil, Y. O. & Al-Nimer, M. S. (2001). Detection The level of peroxynitrite, and related with antioxidant status in the serum of patients with acute myocardial infraction. Nat. J. Chem., (4):625-637.
Dacie, V. & Lewis , S.M. (1995). Practical Hematology. 2 Ed. Philadelphia. Tokyo. P. 352-354.
Rodac, S.B. (2002). Hematological Clinical principles and application. 2nd Ed. W.B. Saunder company. Philadelphia. London. Toronto. P. 156.
Al-Rawi, humbled Mahmoud and Khalaf Allah, Abdul Aziz Muhammad (2000). Design and analysis of agricultural experiments, Ministry of Higher Education and Scientific Research. House of books for printing and publishing. University of Al Mosul. Second Edition. page 488.
Bracamonte, M.P. ; K., S. Rud ; Whyte, G. Owen and V., M. Miller (2002). Ovariectomy increases mitogens and plateletinduced proliferation of arterial smooth muscle. Am J Physiol. Heart Circ Physiol. 283: H853-H860.
O'Brien, J. ; Martinson, H. ; Durand-Rougely, C. ; Schedin, P. (2012). Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution. Development 139(2):269-275.
Diab, Donia Saadoun (2013). The effect of sesame oil on some biochemical parameters of the liver and some Hematological parameters in male rabbits. Karbala University Scientific Journal, Volume (11), No. 3.
Prior, R. and Wux , S. K. (2005). Standardized methods for the determination of
antioxidant capacity and phenolics in foods and dietary supplements. J Agric food chem. 53 (10): 4290-302.
Yen, S. ; Jaffe, R. and Barbieri, R. (1999). Reproductive endocrinology. 4th ed. Philadelphia: Saunders. 110-133; 301-319; 751-784.
Tug, N. ; Celik, H. ; Cikim, G. ; Ozcelik, O. and Ayar, A. (2006). The correlation between plasma homocystine and malondiadehyde levels in preeclampsia. Neuroendocrinolgy Letters., 24 (6): 445-448.
Valko, M. ; Leibritz, D. ; Moncol, J. ; Cronin, M. ; Mazur, M. and Telser, J. (2007). Free radicals and anyloxidants in normal physiological functions and Human disease. Int. J. Biochem. Cell Biol., 39(1):44-84.
Weitzmann, M. & Pacifici, R. (2006). Estrogen deficiency and bone loss : an inflammatory tale. J. Clin. Invest. ;116 (5):1186-1194.
Al-Saadi, Reem Abdel Rahim Mardan (2012). Effect of ovaries removal and iron overload on some physiological and genetic parameters in adult female rabbits. Master Thesis. College of Education for Pure Sciences. Karbala University.
27. Rificia ,V. & Khachadurian, A. (1992). The inhibition of low density lipoprotein oxidation by 17-beta estradiol. Meta. Clin. Exper. ; 41: 1110-1114.
Kaim, Ghosoun Ghanem (2014). Effect of phytoestrogen on some physiological, histological and genetic parameters of female rabbits with induced osteoporosis. PhD thesis. College of Education for Pure Sciences. Karbala University.
Kerksick, C. and Willoughby, D. (2005). The antioxidant vole of glutathione and N- Acetyl-Cysteine Supplements and exercise-Induced oxidative strees. J. Int .Soc. Sports . Nutr. , 2(2): 38-44.
Muhammad Imran ; Muhammad Kamran Khan ; Muhammad Ali ; Muhammad Nadeem ; Zarina Mushtaq ; Muhammad Haseeb Ahmad ; Muhammad Sajid Arshad ; Nazir Ahmad and Muhammad Abdul Rahim. Chapter 10. Cold pressed sesame (Sesamum indicum) oil, Editor(s): Mohamed Fawzy Ramadan, Cold Pressed Oils, Academic Press, 2020, Pages 105-111.
Ramezani, M. and Rezaei Gorgani, M. Physicochemical Properties of Heavy Metals and Aflatoxin Levels in Sesame Oil: A Review Study. J Nutrition Fasting Health. 2018; 6(1): 45-51.
Woo, M. ; Han, S. and Song, YO. (2019). Sesame Oil Attenuates Renal Oxidative Stress Induced by a High Fat Diet. Prev. Nutr. Food Sci. Jun ; 24(2): 114-120.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.