Maternal & fetal risk factors for hypoxic-ischemic encephalopathy (HIE) in newborns: A case-control study from southern Odisha, India

Santosh Kumar Pradhan; Ashok Kumar Nanda; Lal Mohan Alada

doi:10.53730/ijhs.v6nS2.8452

Maternal & fetal risk factors for hypoxic-ischemic encephalopathy (HIE) in newborns

A case-control study from southern Odisha, India

https://doi.org/10.53730/ijhs.v6nS2.8452

Authors

Santosh Kumar Pradhan Asst. Prof., Department of Pediatrics, MKCG Medical College, Berhampur
Ashok Kumar Nanda Asst. Prof., Department of Pediatrics, MKCG Medical College, Berhampur
Lal Mohan Alada Senior Resident, Department of Pediatrics, FM Medical College, Balasore

Keywords:

pediatrics, neonatology, perinatal asphyxia, HIE

Abstract

Introduction- Perinatal hypoxia leading to hypoxic-ischemic encephalopathy (HIE) is a leading cause of neonatal and under 5 mortality across the world and in India. There are wide regional and social variations in the risk factors associated with HIE and this study was conducted to assess the maternal & fetal risk factors in newborns with moderate to severe HIE. Methodology- This was a case-control study at the SNCU of MKCG Medical College and Hospital in southern Odisha where 100 cases of HIE and 100 matched controls were recruited over a period of 2 years. Data on maternal, antenatal, intrapartum, and post-delivery risk factors were collected from medical records and history taking using a pre-defined proforma. Comparative bivariate analysis was done to assess the strength of association of these risk factors between the two groups. Results- The incidence of HIE is more in 20-30 years age group, however, risk of HIE is significant in <20 years age group. Maternal anemia is a significant risk factor but Bad Obstetric History (BOH) has only clinical correlation. There is no statistical significance for antepartum hemorrhage (APH), pregnancy-induced hypertension (PIH) or gestational diabetes mellitus (GDM) in cases of HIE.

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Published

31-05-2022

How to Cite

Pradhan, S. K., Nanda, A. K., & Alada, L. M. (2022). Maternal & fetal risk factors for hypoxic-ischemic encephalopathy (HIE) in newborns: A case-control study from southern Odisha, India. International Journal of Health Sciences, 6(S2), 13076–13082. https://doi.org/10.53730/ijhs.v6nS2.8452

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Issue

Vol. 6 No. S2 (2022)

Section

Peer Review Articles

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