Association of sonographic grading of fatty liver disease with liver function tests and CT hounsfield
Abstract
Fatty Liver Disease (FLD) is described as the accumulation of triglycerides within cytoplasmic vesicles of hepatocytes exceeding 5 percent of total liver weight. It is generally of two types: Alcoholic or Non-alcoholic FLD (NAFLD). It has a tendency to progress and cause steatohepatitis, brosis, cryptogenic cirrhosis, hepatocellular carcinoma, chronic liver disease, metabolic syndrome, polycystic ovarian syndrome and adenocarcinomas. Objective: To nd association of Sonographic Grading of Fatty Liver Disease with Liver Function Tests and CT Hounseld units. The evaluation of the signicance of Ultrasound and LFTs over Computed Tomography is the aim of this study for the diagnosis of Fatty Liver Disease. Method: patients were undergone CT exams, Ultrasound exams and LFT tests for this this study (mean age: Their hepatic Hounseld units were obtained, Ultrasonographic grades were specied and LFTs were recorded. Results: The sonographic grading of fatty liver is significant/ not, taking HU value as standard. Conclusion: It is concluded that Ultrasound is effective in diagnosing this disease in all grades of FattyLiver Disease along with Liver Function Tests.
Downloads
References
Boyce CJ, Pickhardt PJ, Kim DH, Taylor AJ, Winter TC, Bruce RJ, Lindstrom MJ, Hinshaw JL. Hepatic steatosis (fatty liver disease) in asymptomatic adults identied by unenhanced low-dose CT. American Journal of Roentgenology. 2010 Mar;194(3):623-8. doi: 10.2214/AJR.09.2590.
Javed M. Fatty Liver: Yet another Silent Killer. Journal of Ayub Medical College Abbottabad. 2014 Jan 1;26(1):1-2.
Khan SH. Fatty Liver, Nad, Mad And Nash A Menace Far Bigger Than Anticipated: Need For Pre-Emptive Diagnostics. J Ayub Med Coll Abbottabad. 2021 Apr- Jun;33(2):173-174.
Bellentani S. The epidemiology of non-alcoholic fatty liver disease. Liver international. 2017 Jan; 37:81-4. doi: 10.1111/liv.13299.
Lin SC, Heba E, Wolfson T, Ang B, Gamst A, Han A, Erdman Jr JW, O'Brien Jr WD, Andre MP, Sirlin CB, Loomba R. Noninvasive diagnosis of nonalcoholic fatty liver disease and quantication of liver fat using a new quantitative ultrasound technique. Clinical Gastroenterology and Hepatology. 2015 Jul 1;13(7):1337-45. doi: 10.1016/j.cgh.2014.11.027.
McDicken WN, Anderson T. Basic physics of medical ultrasound. Blood. 2011;1570(1.61):105.
Ballestri S, Romagnoli D, Nascimbeni F, Francica G, Lonardo A. Role of ultrasound in the diagnosis and treatment of nonalcoholic fatty liver disease and its complications. Expert review of gastroenterology & hepatology. 2015 May 4;9(5):603-27. doi: 10.1586/17474124.2015.1007955.
Zhang YN, Fowler KJ, Hamilton G, Cui JY, Sy EZ, Balanay M, Hooker JC, Szeverenyi N, Sirlin CB. Liver fat imaging—a clinical overview of ultrasound, CT, and MR imaging. The British journal of radiology. 2018 Sep;91(1089):20170959. doi: 10.1259/bjr.20170959.
Cruz JF, Cruz MA, Machado Neto J, Santana DS, Oliveira CC, Lima SO. Prevalence and sonographic changes compatible with fatty liver disease in patients referred for abdominal ultrasound examination in Aracaju, SE. Radiologia brasileira. 2016 Feb;49(1):1-5. doi: 10.1590/0100-3984.2014.0124
Khov N, Sharma A, Riley TR. Bedside ultrasound in the diagnosis of nonalcoholic fatty liver disease. World journal of gastroenterology: WJG. 2014 Jun 14;20(22):6821. doi: 10.3748/wjg.v20.i22.6821
Bryant JA, Drage NA, Richmond S. CT number denition. Radiation Physics and Chemistry. 2012 Apr Sonographic Grading of Fatty Liver Disease with Liver Function Tests DOI: https://doi.org/10.54393/pbmj.v5i3.174 1;81(4):358-61. doi.org/10.1016/j.radphyschem.2011.12.026
Yousaf M, Maryam S, Fiaz M, Hanif A, Fatima M, Bacha R, Farooq SM, Madina SR, Gilani SA. Comparison of Computed Tomographic Hounseld Numbers with Ultrasonographic Categorization of the Fatty Liver Disease. Journal of Radiology and Clinical Imaging. 2019;2(4):59-70.
Obika M, Noguchi H. Diagnosis and evaluation of nonalcoholic fatty liver disease. Experimental diabetes research. 2011 Oct 27;2012. doi: 10.1016/j.cld.2017.08.004.
Davidson LE, Kuk JL, Church TS, Ross R. Protocol for measurement of liver fat by computed tomography. Journal of applied physiology. 2006 Mar;100(3):864- 8. doi: 10.1152/japplphysiol.00986.2005.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.