Correlation between HbA1c and carotid artery intima-media thickening(cIMT) in diabetic patients

Vishalkumar Bhardava; Shaishavi Shah; Kundan Patel; Ami Pachal; . Keshavi Shah

doi:10.53730/ijhs.v6nS3.8601

Authors

Vishalkumar Bhardava Associate Professor, Department of Radiodiagnosis, S.B.K.S. Medical Institute & Research Centre, sumandeep Vidyapeeth, Pipariya , Waghodia, Vadodara, Gujarat, India
Shaishavi Shah Resident, Department of Radiodiagnosis, S.B.K.S. Medical Institute & Research Centre, sumandeep Vidyapeeth, Pipariya, Waghodia, Vadodara, Gujarat, India
Kundan Patel Resident, Department of Radiodiagnosis, S.B.K.S. Medical Institute & Research Centre, sumandeep Vidyapeeth, Pipariya, Waghodia, Vadodara, Gujarat, India
Ami Pachal Resident, Department of Radiodiagnosis, S.B.K.S. Medical Institute & Research Centre, sumandeep Vidyapeeth, Pipariya, Waghodia, Vadodara, Gujarat, India
. Keshavi Shah Intern Doctor, S.B.K.S. Medical Institute & Research Centre, sumandeep Vidyapeeth, Pipariya, Waghodia, Vadodara, Gujarat, India

Keywords:

carotid artery intimal thickness, diabetic patients, HbA1c levels

Abstract

Introduction: Correlation between carotid artery intima-media thickening and HbA1c levels in diabetic patients as a non invasive marker of progressive atherosclerosis. Objectives: The aim of this study is to study the role of two non invasive markers, carotid intima media thickening and HbA1c in diabetic patients and establish the usefulness of both the parameters in evaluating early risk factor assessment. Material and methods: 100 patients meeting the required criteria were taken coming to OPD/IPD bases to Dhiraj hospital in the age group of 35-70 years.HbA1c levels were used according to American diabetes association. Carotid intima media thickening was measures on B mode ultrasonography in radiology department. Results: among the 100 patients, 68 patients were female and 32 patients were male. The mean of HbA1c values were 8.0 ± 2.2%. The mean cIMT values were 0.78 ± 0.3 cm. Conclusion: HbA1c and carotid artery intimal thickness is useful as a diagnostic marker and early risk factor analysis for atherosclerotic changes in diabetic patients.

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References

Brohall G, Odén A, Fagerberg B. Carotid artery intima-media thickness in patients with Type 2 diabetes mellitus and impaired glucose tolerance: a systematic review. Diabet Med. 2006; 23(6):609-16. PubMed | Google Scholar

Ryden L, Standl E, Bartnik M, Van den Berghe G, Betteridge J, de Boer MJ et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary; The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology ESC and of the European Association for the Study of Diabetes EASD. Eur Heart J. 2007; 28(1):88-136. PubMed | Google Scholar.

Mukai N, Ninomiya T, Hata J, Hirakawa Y, Ikeda F, Fukuhara M et al. Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: the Hisayama Study. Cardiovasc Diabetol. 2015; 14:84. PubMed | Google Scholar

Huang Y, Bi Y, Wang W, Xu M, Xu Y, Li M et al. Glycated hemoglobin A1c, fasting plasma glucose, and two-hour postchallenge plasma glucose levels in relation to carotid intima-media thickness in chinese with normal glucose tolerance. J Clin Endocrinol Metab. 2011; 96(9):1461-5. PubMed | Google Scholar.

Venkataraman V, Amutha A, Anbalagan VP, Deepa M, Anjana RM, Unnikrishnan R,Vamsi M, Mohan V. Association of glycated hemoglobin with carotid intimal medial thickness in Asian Indians with normal glucose tolerance. J Diabetes Complications. 2012; 26(6):526-30. PubMed | Google Scholar

Ma X, Shen Y, Hu X, Hao Y, Luo Y, Tang J et al. Associations of glycated haemoglobin A1c and glycated albumin with subclinical atherosclerosis in middle-aged and elderly Chinese population with impaired glucose regulation. Clin Exp Pharmacol Physiol. 2015; 42(6):582-7. PubMed | Google Scholar.

Lorenz MW et al. Carotid Intima-Media Thickening Indicates a Higher Vascular Risk Across a Wide Age Range. Stroke 2006;37:87-92.

Jung CH, Son JW, Kang S, Kim WJ, Kim HS, Kim HS, et al. Diabetes fact sheets in Korea, 2020: an appraisal of current status. Diabetes Metab J. 2021;45:1–10. [PMC free article] [PubMed] [Google Scholar].

Brannick B, Dagogo-Jack S. Prediabetes and cardiovascular disease: pathophysiology and interventions for prevention and risk reduction. Endocrinol Metab Clin North Am. 2018;47:33–50. [PMC free article] [PubMed] [Google Scholar]

Suryasa, W. (2019). Historical Religion Dynamics: Phenomenon in Bali Island. Journal of Advanced Research in Dynamical and Control Systems, 11(6), 1679-1685.

Suryasa, W., Sudipa, I. N., Puspani, I. A. M., & Netra, I. (2019). Towards a Change of Emotion in Translation of Kṛṣṇa Text. Journal of Advanced Research in Dynamical and Control Systems, 11(2), 1221-1231.