Estimation of levels of vitamin E in grade II & III haemorrhoids

A prospective study

https://doi.org/10.53730/ijhs.v6nS2.8534

Authors

  • Muddala Varaprasanna Rao Research Scholar, School of Pharmaceutical Sciences, Vels Institute of Science, Technology And Advanced Studies (VISTAS), Pallavaram, Chennai-600117, India
  • S. Jeganath Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science, Technology And Advanced Studies (VISTAS), Pallavaram, Chennai-600117, India

Keywords:

haemorrhoids, healthy volunteers, alpha-tocopherol, reactive oxygen species, lipid peroxidation

Abstract

Objective: The aim and objective of the study is to estimate the levels of vitamin E in blood in grade II & III haemorrhoid patients. Methods: This study was a prospective observational study carried out in Chennai private hospital for a period of 4 months. Institutional Ethical Committee (VISTAS-SPS/IEC/VII/2020/06) approval was obtained before conducting the study. A total of 70 subjects were enrolled based on the inclusion and exclusion criteria and were randomized into 2 groups Group 1 includes healthy volunteers and Group 2 includes haemorrhoid patients. By observing the vitamin E levels in both the groups, the role of vitamin E in haemorrhoids is determined. Results: In total, 70 patients were randomized into Group 1 and Group 2 with 35 patients each. Among 70 patients 40 patients were males and 30 patients were females. In that 18 patients in age group 18-25 years, 26 patients in age group 26-35 years, 20 patients in age group 36-45 years and 6 patients were above 45 years of age. 

Downloads

Download data is not yet available.

References

Schubert, MC; Sridhar, S; Schade, RR; Wexner, SD (July 2009). "What every gastroenterologist needs to know about common anorectal disorders". World J Gastroenterol. 15 (26): 3201–09.

Chen, Herbert (2010). Illustrative Handbook of General Surgery. Berlin: Springer. p. 217. ISBN 978-1-84882-088-3.

Orlay, G. Aust. Fam. Physician. 2003; 32: 523

Vertuani, S., Bosco, E., Testoni, M., Ascanelli, S., Azzena, G., Manfredini, S. Nutrafoods. 2004; 3(3): 19.

Lohsiriwat V. Hemorrhoids: From basic pathophysiology to clini cal management. World J Gastroenterol 2012; 18(17): 2009-2017.

Sen, C.K., Packer, L. American J. Clinc. Nutr. 2000; 72: 653. 7. Michael J. Ryan, Holly J. Dudash, Megan Docherty, et al. Vitamin E and C supplementation reduces oxidative stress, improves antioxidant enzymes and positive muscle work in chronically loaded muscles of aged rats. Exp Gerontol. 2010 November ; 45(11): 882–895.

C K Chow (1991). “Vitamin E and oxidative stress”. Free Radic Biol Med 1991;11(2):215-32.

U Singh, S Devaraj, I Jialal (2005). “Vitamin E, oxidative stress, and inflammation”. Annu Rev Nutr 2005;25:151-74.

Michael J. Ryan, Holly J. Dudash, Megan Docherty, Kenneth B. Geronilla, Brent A. Baker, G. Gregory Haff, Robert G. Cutlip, and Stephen E. Always (November 2010). “Vitamin E and C supplementation reduces oxidative stress, improves antioxidant enzymes and positive muscle work in chronically loaded muscles of aged rats”. Exp Gerontol. 2010 November ; 45(11): 882–895.

Shanna, R.K., Agarwal, A. Urology 1996; 48: 835.

Niki, E. World rev. Nutr. Diet. 1991; 64: 1-30.

Bartesaghi, S., Trujillo,M., Denicola,A., Folkes, L., Wardman, P. and Radi, R. Free Radic. Biol. and Med. 2004; 36(4): 471.

Ling Li, Free Radic. and Radia. Biol. Program 2001, B180 Medical Laboratories, University of Lowa,PP.1-10.

Published

07-06-2022

How to Cite

Rao, M. V., & Jeganath, S. (2022). Estimation of levels of vitamin E in grade II & III haemorrhoids: A prospective study. International Journal of Health Sciences, 6(S2), 13417–13421. https://doi.org/10.53730/ijhs.v6nS2.8534

Issue

Section

Peer Review Articles