In vivo antipyretic activity of Scutia myrtina acute oral toxicity study

https://doi.org/10.53730/ijhs.v6nS3.8548

Authors

  • Pravin G. Dhone Professor & Head, Department of Pharmacology, RSDKS GMC, Ambikapur
  • Abha Ekka Assistant professor, Department of PSM, RSDKS GMC, Ambikapur
  • P. K. Sinha Associate professor, Department of Skin and VD (Dermatology), RSDKS GMC, Ambikapur
  • Annapurna Sahoo MD Pharmacology, District Head Quarter Hospital, Bargarh, Odisha

Keywords:

pyrexia, antipyretic, hydroalcoholic

Abstract

Pyrexia or Fever is defined as an elevation of body temperature. It is a response due to tissue damage, inflammation, malignancy or graft rejection. Cytokines, interleukin, interferon and Tumor Necrosis Factor α (TNF- α) are formed in large amount under this condition, which increase PGE2 which in turn triggers hypothalamus to elevate body temperature. The present investigation it may be concluded that the hydroalcoholic extract of leaves of Scutia myrtina has antipyretic activity.it is tested by in vivo method by using rat .In this study the hydroalcoholic extract contain fever reducing activity.

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Published

07-06-2022

How to Cite

Dhone, P. G., Ekka, A., Sinha, P. K., & Sahoo, A. (2022). In vivo antipyretic activity of Scutia myrtina acute oral toxicity study. International Journal of Health Sciences, 6(S3), 9706–9711. https://doi.org/10.53730/ijhs.v6nS3.8548

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