In vivo antipyretic activity of Scutia myrtina acute oral toxicity study
Keywords:
pyrexia, antipyretic, hydroalcoholicAbstract
Pyrexia or Fever is defined as an elevation of body temperature. It is a response due to tissue damage, inflammation, malignancy or graft rejection. Cytokines, interleukin, interferon and Tumor Necrosis Factor α (TNF- α) are formed in large amount under this condition, which increase PGE2 which in turn triggers hypothalamus to elevate body temperature. The present investigation it may be concluded that the hydroalcoholic extract of leaves of Scutia myrtina has antipyretic activity.it is tested by in vivo method by using rat .In this study the hydroalcoholic extract contain fever reducing activity.
Downloads
References
World Health Organization: Quality control methods for medicinal plant materials. Published by WHO, Geneva, 1998.
El SN and Karakava S. Radical scavenging and ironchelating activities of some greens used as traditional dishes in Mediterranean diet. Int J Food Sci Nutr, 2004, 55: 67.
Samy PR, Iushparaj PN, Gopalakrishnakone PA. Compilation of bioactive compounds from Ayurveda Bioinformation, 2008.
Subhose V, Narian A. Basic principles of pharmaceutical science in Ayurvĕda. Bull Indian Inst Hist Med Hyderbad, 2005, 35: 83.
Ballabh B and Chaurasia OP. Traditional medicinal plants of cold desert Ladakh--used in treatment of cold, cough and fever. J Ethnopharmacol, 2007, 112: 341.
Chhabra SC, Mahunnah RLA, Mshiu EN. (1991) Plants used in Traditional Medicine in Eastern Tanzania. V. Angiosperms (Passifloraceae to Sapindaceae). J. Ethnopharmacol. 7, 143-157.
Cuman, RKN, Bersani-Amadio CA, Fortes ZB. (2001) Influence of type 2 diabetes on the inflammatory response in rats. Inflam. Res. 50, 460-465. Dunne MW. Pathophysiology: Concepta of altered Health States with Contributors, In: Porth CM, Lippincott eds. Philadlphia, pp. 165-176. Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Ray C. (1968) Screening of Indian plants for biological activity Indian J. Exp. Biol. 6, 232-247. Hedberg I,
Hedberg O, Mashigeni KE, Mshiu, EN, Samuelsson G, (1983) Inventory of plants usedin traditional medicine in Tanzania, part III Plants the families Papilionaceae-Vitaceae. J. Ethnopharmacol. 9, 237-260.
El-shenawy SM, Abdel-salam OM, Baiuomy AR, El-batran S, Arbid MS (2002) Studies on the antiinflammatory and anti-nociceptive effects of melatonin in the rat. J. Pharmacol. 46, 235-243.
Gakunju DMN, Mberu EK, Dossaji SF, Gray AI, Waigh RD, Waterman PG, Watkins WM. (1995) Potent antimalarial activity of the Alkaloid Nitidine, Isolated from a Kenyan herbal remedy. Antimicrob. Agent’s Chimother. 39, 2606-2609.
Kaij-A-Kamb M, Amoros M, Girre L. (1992) Search for new antiviral agents of plant origin. Pharma. Acta. Helv. 67, 130-147
Suleyman H, Demirezer LO, Kuruuzum A, Banoglu ZN, Gocer F, Ozbakir G, Gepdireman A. (1991) Anti-inflammatory effect of the aqueous extract from Rumex patientia L. roots, J. Ethnopharmacol. 65, 141-148.
Recio MC, Giner GM, Manez S, Ros JL. (1995) Structural requirements for the anti-inflammatory activity of natural terpenoids. Planta. Med. 6, 182-185.
Winter CA, Poster CC. (1957) Effect of alteration in side chain up on anti-inflammatory and liver glycogen activities in hydrocortisone ester. J. Am. Pharmacol. Soc. 46, 515-519.
Winter CA, Risely EA, Nuss GW. (1962) Carrageenan induced oedema in hind paw of the rat as assays for anti-inflammatory drugs. Exp. Biol. Med. 111, 544-547.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
