A review article on
Phytochemical and pharmacological activities of carica papaya
Keywords:
carica papaya, pharmacognosy, pharmacology, phytochemistry, ethanopharmacologyAbstract
These are well-known health benefits of papaya (Carica papaya Linn.). Ayurveda, for example, recognises papaya's therapeutic value. Herbalists have used it to cure bilious fever, gonorrhoea, eczema, rheumatism and headaches. It took four decades of amazing research to identify a critical nutraceutical compound. It is antibacterial, antipyretic, insecticidal, antimicrobial, and antimolluscan. Leaves have been studied using phytoextraction of heavy metals and phytoremediation of particle pollution. Long-term research on phytoconstituents and leaf composition. Malaria, dengue fever, inflammation, and skin infections are all treated by Carica papaya. C. papaya flowers were first tested for antioxidant and antibacterial properties using TLC and UV spectroscopy. Our tests included TLC and UV-visible spectroscopy. The methanol extract had the most alkaloids, flavonoids, saponins, and tannins. N-hexane had steroids and flavonoids while chloroform had saponins and tannins. In it, there were flavonoids and phenolic compounds.
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Bedi R: Bedi vanaspati kosh. Kitabghar publication, New Delhi; First edition 2005; 1: 440-453.
Pullaiah T: Encyclopaedia of world medicinal plants. Regency publication, New Delhi 2006; 1: 446-449.
The wealth of India, raw materials Ca-Ci: CSIR, New Delhi 1992; 3: 290. ISBN-81-85038-97-X
Trikamji AY: Dravyagunavigyanamuttaraardha. Sharma ayurved mandir datiya (MP) 2001; 5: 212-213.
Bapalal VG: Nighantu Adarsh Chaukhambhabharati Academy, Varanasi, Reprint 2007; 1: 613-616.
Reddy RK: Folk medicines from Chittoor district, Andhra Pradesh, India, used in the treatment of Jaundice. International Journal of Crude Drug Research 1988; 26: 137-140.
Raj, KPS and Patel MR: Some medicinal plants of Cambay and its immediate vicinity and their uses in Indian indigenous system of medicine. Indian drugs 1978; 15: 145-152, 160.
Pal SC and Srivastava SN: Preliminary notes on the ethnobotany of Singhbhum District, Bihar. Bull. Bot. Surv. India 1976; 18: 247-250.
Megoneitso and Rao RR: Ethnobotanical studies in Nagaland, sixty two medicinal plants used by the Angamia Naga, J. Econ. Taxon. Bot. 1983; 4(1): 167-172.
Ghoti H, Fibach E, Dana M, Abu Shaban M and Jeadi H: Oxidative stress contributes to hemolysis in patients with hereditary spherocytosis and can be ameliorated by fermented papaya preparation. Ann Hematol 2011; 90: 509-513.
Aruoma OI, Hayashi Y, Marotta F, Mantello P and Rachmilewitz E: Applications and bioefficacy of the functional food supplement fermented papaya preparation. Toxicology 2010; 278: 6-16.
Iweala EE, Uhegbu FO and Ogu GN: Preliminary in-vitro antisickilng properties of crude juice extracts of Persia Americana, Citrus sinensis, Carica papaya L. and Ciklavit (R). Afr J Tradit Complement Altern Med 2010; 7: 113- 117.
Sripanidkulchai B, Wongpanich V, Laupattarakasem P, Suwansaksri J and Jirakulsomchok D: Diuretic effects of selected Thai indigenous medicinal plants in rats. J Ethnopharmacol 2001; 75: 185-190.
Sharma PV: Ayurved ka Vaigyanikitihasa; Chaukhambha Orientalia, Varanasi 1996; 3: 380.
Shaligram VL: Shaligramnighantubhushan; khemrajsrikrishnadass, Mumbai 2011; 928-929.
Sharma PV: Priyanighantu; Chaukhambhasurabharatiprakashan, Varanasi 2004; 193.
Anjum V, Ansari SH, Naquvi KJ, Arora P and Ahmad A: Development of quality standards of Carica papaya L Leaves; Scholars Research Library, Der Pharmacia Lettre 2013; 5(2): 370-376.
Zunjar V, Mammen D, Trivedi BM and Daniel M: Pharmacognostic, Physicochemical and Phytochemical studies on Carica papaya Linn. leaves: Pharmacognosy Journal 2011; 3(20): 5-8.
Awuchi, C. G., Amagwula, I. O., Priya, P., Kumar, R., Yezdani, U., & Khan, M. G. (2020). Aflatoxins in foods and feeds: A review on health implications, detection, and control. Bull Environ Pharmacol Life Sci, 9(9), 149-155.
Ram PN, Ram VR, Khatri TT, Vyas SJ and Dave PN: XRF analysis of Carica papaya L. leaves of semi arid region of Kachchh; International Letters of Natural Sciences 2014; 19: 15-24.
Vishwanath Z, Prasad DR, Mehul J, Trivedi B and Nivsarkar M: Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats; journal of ethanopharmacology 2016; 181(2): 20-25.
Dharmarathna SLCA, Wickramasinghe S, Waduge RN, Rajapakse RPVJ and Kularatne SAM: Does Carica papaya L. leaf extract increase the platelet count? An experimental study in a murine model; Asian Pacific Journal of Tropical Biomedicine 2013; 3(9):720-724.
Saha, P., Kumar, R., Nyarko, R. O., Kahwa, I., & Owusu, P. (2021). Herbal secondary metabolite for gastro-protective ulcer activity with api structures. 2015; 16: 213-222
Suwendar PH and Ernasari GI: Analgetic activity of Papaya (Carica papaya L.) leaves extract; Procedia Chemistry 2014; 13: 147-149.
Otsuki N, Dang NH and Morimoto EKASC: Aqueous extract of Carica papaya L. leaves exhibits anti tumor activity and immunomodulatory effects; Journal of Ethnopharmacology 2010; 127(3): 760-767.
Pandey S, Walpole C, Cabot PJ, Shaw PN, Jyotsna B and Hewavitharana AK: Cancer; Biomedicine and Pharmacotherapy 2017; 89: 515-523.
Abidina NZ, Omara H, Empungana AJ, Kamalaldinb NA, Yahayab BH and Zubairia SI: Proliferative Activity of Saponin-Reducing Carica papaya L. Leaves Extracts on Human Lung Fibroblast Cell (IMR90). Journal Teknologi November 2016.
Juarez-Rojop IE: Phytochemical screening and hypoglycaemic activity of Carica papaya L. leaf in streptozotocin- induced diabetic rats; RevistaBrasileira de Farmacognosia 2014; 24(3): 341-347
Sahana, S., Kumar, R., Nag, S., Paul, R., Chatterjee, I., & Guha, N. (2020). A Review On Alzheimer Disease And Future Prospects.2017;77-82
Dinesh, M.R.; Vani, A.; Aswath, C.; Rawal, R.D. Biology of Carica papaya (Papaya). Ministry of Environment, Forest and Climate Change (MoEF&CC), 2015, pp. 1-20.
Milind, P.; Gurditta, G. Basketful benefits of papaya. International Research Journal of Pharmacy, 2011, 2(7), 6-12.
Rimberia, F.K.; Adaniya, S.; Ishimine, Y.; Etoh, T. Morphology of papaya plants derived via anther culture, Sci. Hortic., 2007, 111, 213-219.
Kayalvizhi, K.; Cathrine, L.; Banu, K.S. Phytochemical and antibacterial studies on the leaf extracts of female Carica papaya Linn. Int. J. PharmTech Res., 2015, 8(7), 166-170.
Anjum, V.; Ansari, S.H.; Naquvi, K.J.; Arora, P.; Ahmad, A. Development of quality standards of Carica papaya Linn. leaves. Sch. Res. Lib., 2013, 5(2), 370-376.
Kumar, Roshan, PurabiSaha, Yogendra Kumar, Soumitra Sahana, Anubhav Dubey, and Om Prakash. "A review on diabetes mellitus: type1 & type2." (2020). 12-15
Saini, R.; Mittal, A.; Rathi, V. Phytochemical evaluation of Carica Papaya extracts. Eur. J. Pharm. Med. Res., 2016; 3(3), 346-350.
Saeed, F.; Arshad, M.U.; Pasha, I.; Naz, R.; Batool, R.; Khan, A.A.; Nasir, M.A.; Shafique, B. Nutritional and phyto-therapeutic potential of Papaya (Carica papaya Linn.): An Overview. Int. J. Food Prop., 2014, 17(7), 1637-1653.
Osato, J.A.; Santiago, L.A.; Remo, G.M.; Cuadra, M.S.; Mori, A. Antimicrobial and antioxidant activities of unripe papaya. Life Sci., 1993, 53(17), 1383-1389.
Krishna, K.L.; Paridhavi, M.; Patel, J.A. Review on nutritional, medicinal and pharmacological properties of Papaya (Carica papaya Linn.). Nat. Prod. Rad., 2008, 7(4), 363-373.
Rinartha, K., Suryasa, W., & Kartika, L. G. S. (2018). Comparative Analysis of String Similarity on Dynamic Query Suggestions. In 2018 Electrical Power, Electronics, Communications, Controls and Informatics Seminar (EECCIS) (pp. 399-404). IEEE.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938
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