Study of neurological behaviors resulting from neurotoxicity induced by methyl bromide in rats
Keywords:
neurotoxicity, methyl bromide, brain tissue, rat, IraqAbstract
Bromide and chloride are chemically related halide elements that the kidney works with to keep the overall body halide content balanced. Also Bromide is a element that known to cause many neurotoxic and other organs toxicity such as GIT tract, respiratory tract and liver. Therefore, we aimed in the present study on the effect of bromide at daily intake doses to investigate possible neurotoxic effect and modulate its possible mechanism and Ameliorative trail of Sodium chloride .Chloride-containing diuretics, In conclusion, the results of the present study indicated that the levels of methyl bromide might induced neurobehavioral changes and disturbance in the oxidant and antioxidant mechanism due to the ability of methyl bromide to accumulate in the brain tissue that causes structural brain damage or disturbing of CNS activity and ameliorative trail of sodium chloride to neurotoxicity
Downloads
References
Al- Bakkoh, B.K. (2002) .Neurobehavioral and biochemical changes induced byinteraction of calicium and some insecticide in mice. Ph.D. dissertation,College of Veterinary Medicine, Mousl University. Mousl ,Iraq .
Beverly Kulig, Enrico Alleva, Giorgio Bignami, Jeffrey Cohn, Deborah Cory-Slechta, V. Landa, John O'Donoghue and David Peakall1996
Chaudhari, A. K., Singh, V. K., Kedia, A., Das, S., & Dubey, N. K. (2021). Essential oils and their bioactive compounds as eco-friendly novel green pesticides for management of storage insect pests: prospects and retrospects. Environmental Science and Pollution Research, 28(15), 18918-18940.
Chen, Y.H.; Huang, E.Y.; Kuo, T.T.; Miller, J.; Chiang, Y.H.; Hoffer, B.J. Impact of Traumatic Brain Injury on Dopaminergic Transmission. Cell Transpl. 2017, 26, 1156–1168.
Deacon R and Rawlins J. (2006). T-maze alternation in the rodent. Nat Protoc. ;1(1):7 12.
Decker, J. M., Krüger, L., Sydow, A., Zhao, S., Frotscher, M., Mandelkow, E., and Mandelkow, E. M. (2015). Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation. Acta neuropathologica communications, 3(1), 1-18.
Dellu, F., Mayo, W., Cherkaoui, J., LeMoal, M., and Simon, H. (1992). A two-trial memory task with automated recording: Study in young and aged rats. Brain Research, 588, 132-139
Gamliel, A. (2020). Soil and substrate health. In Integrated Pest and Disease Management in Greenhouse Crops (pp. 355-383). Springer
Gharban, H.A.J., and Al-Shaeli, S.J.J. (2021). Clinical and serum biochemical evaluation of goats with hypomagnesemia. Biochem. Cell. Arch., 21 (1), 587-592.
Iemolo, A., De Risi, M., & De Leonibus, E. (2015). Role of Dopamine in Memory Consolidation. Memory Consolidation; Nova Science Publishers, Inc.: New York, NY, USA
Lam, A.; Vetal, N.; Matalon, S.; Aggarwal, S. Role of heme in bromine-induced lung injury. Ann. N. Y. Acad. Sci. 2016, 1374,105–110
Mohammad, F. K. (1986). ASSESSMENT OF BEHAVIORAL, NEUROCHEMICAL AND DEVELOPMENTAL EFFECTS IN DEVELOPING RATS FOLLOWING IN UTERO EXPOSURE TO NON-TERATOGENIC LEVELS OF 2, 4-D AND 2, 4, 5-T (HERBICIDES, ONTOGENY).
Mumby, D. G., Wood, E. R., and Pinel, J. P. J. (1992). Objectrecognition memory is only mildly impaired in rats with lesions of the hippocampus and amygdala. Psychobiology, 20(1), 18-27.
Nolan, R.; Gaskill, P. The role of catecholamines in HIV neuropathogenesis. Brain Res. 2019, 1702, 54–73.
Safdari, F., Rabbani, M., & Hosseini-Sharifabad, A. (2017). Effect of acute and long term potassium bromide administration on spatial working memory in rat. Research in Pharmaceutical Sciences, 12(2), 154 y maze and head picking
Saleh, M. M., Darwish, S. S., & Elzoghby, M. (2022). The effectiveness of some crystallization inhibitors in preventing salt damage to limestone. Journal of Crystal Growth, 585, 126606
Toshiko Ikeda, Reiko Kishi, Kotaro yamamura ,Hirotsugu Miyake. Minoru Sato and Sumiko Ishizu 1980 .
Upadha yay, J., Rana, M., Juyal, V., Bisht, S. S., & Joshi, R. (2020). Impact of pesticide exposure and associated health effects. Pesticides in crop production: physiological and biochemical action, 69-88
Vohress,C.; Brunner,R. and Butcher, B. (1979). psychotopic drugs as behavioral teratogenes. sci. (205): 12220-25.
Waløen, K.; Kleppe, R.; Martinez, A.; Haavik, J. Tyrosine and tryptophan hydroxylases as therapeutic targets in human disease.Expert Opin. Ther. Targets 2016, 21, 167–180
Werner, S., & Nies, E. (2018). Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals. Journal of Occupational Medicine and Toxicology, 13(1), 1-26.
Whishaw, I. and Tomie, J. (1997). Of mice and mazes: Similarities between mice and rats on dry land but not water mazes. Physiol. Behav. (60): 1191–1197.
Wilson K. Rumbeiha 3, Samina Salim 4, Aftab Ahmad 1 and Shama Ahmad 2021
Razan falah hasan(2021).Neurological Effect of Two Doses of Aluminum Chloride in
Adult Female Rats.vol. N. :Iraq .J. Vet .Med.
Adnan abed ahmed(2016).Evaluation of the bactericidal effect of nisin and or potassium sorbate and sodium chloride on the viability of staphylococcus aureus in soft cheese. Vol.41No.1 :Iraq. J. Vet .Med
Al-Judi, M. H. . (2011). Concentrations of Some Minerals According to Body Condition in Local Sheep: M H Al-Judi , Zainab M , Wassan,A G. vol.35No2:The Iraqi Journal of Veterinary Medicine,
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). The COVID-19 pandemic. International Journal of Health Sciences, 5(2), vi-ix. https://doi.org/10.53730/ijhs.v5n2.2937
Ahmed, A. J. (2017). Evaluation of the bactericidal effect of Nisin and /or Potassium sorbate and Sodium chloride on the viability of Staphylococcus aureus in soft cheese: Zina Saab Khudhir and Adnan Jawad Ahmed. The Iraqi Journal of Veterinary Medicine, Vol.41No1
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.