To evaluate the resistivity of Klebsiella pneumonia against present antibiogram: Case report study

Raj Kumar Wasan; Mohammed Abidullah; Amritpal Kaur; Charanjeet Kaur; Juhi Kataria; Varinder Kaur

doi:10.53730/ijhs.v6nS5.8757

Authors

Raj Kumar Wasan
wasanraj_1984@yahoo.co.in
Ph.D. Microbiology, Reader, Department of Microbiology, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India
Mohammed Abidullah Assistant professor (Oral Pathology and microbiology), Department of Dental and Biomedical Sciences, Faculty of Dentistry, Al Baha University, Al Baha, Saudi Arabia.
Amritpal Kaur MSc Lecturer, Department of Biochemistry, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India
Charanjeet Kaur Assistant Professor, Khalsa College of Pharmacy, Amritsar, Punjab, India
Juhi Kataria Assistant Professor, Khalsa College of Pharmacy, Amritsar, Punjab, India
Varinder Kaur MSc Lecturer, Department of Microbiology, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India

Keywords:

Klebsiellapneumoniae, pan-drug resistance, infection, intensive care unit

Abstract

Klebsiella pneumoniae has become a health care concern due to its production of extended-spectrum beta-lactamase (ESBL) and its resistance to carbapenem. In February 2022, a 28-year-old female patient was admitted to the CCU private ward at Anil Bhagi Hospital in Firozpur, Punjab, India. The urine sample was inoculated with CLED agar medium for microbiological investigation. B D Phoenix sophisticated automated microbiology system was utilised for identification and sensitivity of bacteria for 24 hours for confirmation of bacteria and antibiotic sensitivity. Fosfomycin, teigocyclin and colistin were sensitive whereas other antibiotics were resistant. The observed radiuses were 13mm, 12mm, and 8mm, respectively. A urine culture revealed a highly resistant K. pneumoniae strain with over 1100,000 colony-forming units (cfu) per mL. In February 2022, a 38-year-old female patient was admitted to the CCU private ward. The 7-8 ml blood sample was collected in blood culture bottles for microbiological examination and cultured for 5 days in the B D Phoenix sophisticated automated microbiology equipment. Fosfomycin, teigocyclin and colistin were sensitive while other antibiotics were resistant. The radius observed was 9mm, 4 mm and 8 mm respectively.

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