Incidence of HPV 16 gene among cervix cancer patients of Kanpur – A cross-sectional study
Keywords:
HPV 16 gene, cervix cancer, correlation, cervix cytology, PCRAbstract
Cervix cancer is the common cancer type among women in India, the present study was aimed to demonstrate the incidence of HPV 16 in cervix cancer women of Kanpur which will be helpful for implementing screening programs, vaccinations as well as prognosis of the treatments. The study was conducted in 300 cervix cancer confirmed cases of Kanpur. The diagnosis was confirmed with clinical presentation and cytological examinations. The HPV 16 was confirmed with the real time polymerase chain reaction method. The incidence of HPV 16 was correlated with cytological features. Spearman’s rank correlation test was used for correlating the findings. The data was expressed in frequency and percentage. Majority of study population were in age group of 41-60years. The incidence of HPV 16 was 34% among cervix cancer patients. The cervix cytological features like inflammatory smear, atrophic smear and intraepithelial lesion and malignancies positively correlated with HPV 16 incidence. The conclusions of the present study may be helpful for planning the screening methods and also for implementing the HPV vaccination programs in Kanpur.
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