Risk factor analysis for neonatal sepsis and the outcome in tertiary care neonatal nursery
Keywords:
Neonatal sepsis, Gram negative bacteria, Diagnosis, PregnancyAbstract
Background: Adequate care has to be taken to the new born child because there is large number of mortality in the age group of less than 5. Further most prevalent group is babies within day zero to day 28 after birth. Aim and Objective: The present study was undertaken to observe the risk factor analysis for neonatal sepsis and the outcome in tertiary care neonatal nursery. Material and Methods: New born babies with standard signs and symptoms of sepsis were part of the study after obtaining consent from their parents. The study was conducted between April 2019 to June 2020. Venous blood was drawn from the newborn babies after proper consent from parents and assessed for sepsis. These newborn babies were managed as per the hospital protocol and a predesigned and standard questionnaire was used to collect the data about the risk factors. Results: The most common organism isolated from blood culture was Klebsiella (36.9%). Other organisms isolated were Acinetobacter, Pseudomonas, E.coli, Staphylococcus aureus, Proteus and Citrobacter. 1% had culture positive for Non Candida albicans. Conclusion: The most common organism isolated from blood culture was Klebsiella (36.9%).
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References
Edmond K, Zaidi A. New approaches to preventing, diagnosing, and treating neonatal sepsis. PLoS Med. 2010;7:e1000213
Neonatal Sepsis in Newborn, AIIMS Protocol in India. 2014. [Last cited 2019 Jun 15]. Available from: http://www.newbornwhocc.org/2014_pdf/Neonatal%20sepsis%202014.pdf .
Sanghvi KP, Tudehope DI. Neonatal bacterial sepsis in a neonatal intensive care unit: A 5 year analysis. J Paediatr Child Health. 1996;32:333–8.
West B, Tabansi P. Prevalence of neonatal septicaemia in the University of port harcourt teaching hospital, Nigeria. Niger J Paediatr. 2013;41:33.
Simonsen KA, Anderson-Berry AL, Delair SF, Davies HD. Early-onset neonatal sepsis. Clin Microbiol Rev. 2014;27:21–47.
erma P, Berwal P, Nagaraj N, Swami S, Jivaji P, Narayan S. Neonatal sepsis: epidemiology, clinical spectrum, recent antimicrobial agents and their antibiotic susceptibility pattern. Int J Contemp Pediatr. 2015;365:176–80.
Leal YA, Álvarez-Nemegyei J, Velázquez JR, Rosado-Quiab U, Diego-Rodríguez N, Paz-Baeza E, et al. Risk factors and prognosis for neonatal sepsis in southeastern mexico: Analysis of a four-year historic cohort follow-up. BMC Pregnancy Childbirth. 2012;12:48.
Stefanovic IM. Neonatal sepsis. Biochem medica. 2011;21:276–81.
Onalo R, Ogala WN, Ogunrinde GO, Olayinka AT, Adama SA, Ega BA. Predisposing factors to neonatal septicaemia at ahmadu bello University teaching hospital, Zaria Nigeria. Niger Postgrad Med J. 2011;18:20–5.
Omoregie R, Egbe CA, Dirisu J, Ogefere HO. Microbiology of neonatal septicemia in a tertiary hospital in Benin City, Nigeria. Biomarkers Genomic Med. 2013;5:142–6.
Pius S, Bello M, Galadima GB, Ibrahim HA, Yerima ST, Ambe JP. Neonatal septicaemia, bacterial isolates and antibiogram sensitivity in Maiduguri North-Eastern Nigeria. Niger Postgrad Med J. 2016;23:146–51.
Garba B, Muhammad A, Mohammed B, Obasi A, Adeniji A. A study of neonatal mortality in a specialist hospital in Gusau, Zamfara, North-Western Nigeria. Int J Trop Dis Heal. 2017;28:1–6.
Ogunlesi TA, Ogunfowora OB. Predictors of mortality in neonatal septicemia in an underresourced setting. J Natl Med Assoc. 2010;102:915–21.
Charan J, Biswas T. How to calculate sample size for different study designs in medical research? Indian J Psychol Med. 2013;35:121–6.
Gebrehiwot A, Lakew W, Moges F, Moges B, Anagaw B, Unakal C, et al. Predictors of positive blood culture and death among neonates with suspected neonatal sepsis in Gondar University hospital, Northwest Ethiopia. Euro J Exp Bio. 2012;2:2212–8.
Jajoo M, Kapoor K, Garg L, Manchanda V, Mittal S. To study the incidence and risk factors of early onset neonatal sepsis in an out born neonatal intensive care unit of India. J Clin Neonatol. 2015;4:91.
Kayange N, Kamugisha E, Mwizamholya DL, Jeremiah S, Mshana SE. Predictors of positive blood culture and deaths among neonates with suspected neonatal sepsis in a tertiary hospital, Mwanza-Tanzania. BMC Pediatr. 2010;10:39.
Al-Zwaini EJ. Neonatal septicaemia in the neonatal care unit, al-anbar governorate, Iraq. East Mediterr Health J. 2002;8:509–14.
John B, David M, Mathias L, Elizabeth N. Risk factors and practices contributing to newborn sepsis in a rural district of Eastern Uganda, august 2013: A cross sectional study. BMC Res Notes. 2015;8:339.
Karthikeyan G, Premkumar K. Neonatal sepsis: Staphylococcus aureus as the predominant pathogen. Indian J Pediatr. 2001;68:715–7.
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