The correlation between IFN-γ and the severity of COVID-19 infected patients
Keywords:
SARS-CoV-2, COVID-19, respiratory coronavirus, pneumonia, IFN-γAbstract
This study was carried out at Wasit Province / Iraq in cooperation with alzahraa hospital and Fairouz Hospital/ unit of microbiology. The aim of this study was to evaluate the serum levels of interferon (IFN-γ), and to evaluate the protective Role of this cytokine, in patients infected with (SARS-CoV-2). Samples were collected from many places at Wasit province. It included 66 blood samples from Iraqi patients with covid-19, and 22 healthy subjects as a control. The study was conducted during the period from October 2021 - January 2022, The age range in both groups was (14–72) years. The patients were classified into mild group (22 patients),moderate group(22 patients) and severe group (22 patients). Serum samples were collected from all participants and tested for the cytokine levels by ELISA (enzyme-linked immunosorbent assay) method. The mean serum levels of (IFN-γ), in the (COVID‐19), patients were significantly higher than those observed in the control group Also, there was no difference in (IFN-γ) levels between severe and moderates groups and this levels is slightly lower than mild group . There were significant differences in the means of the three selected variables between samples with (COVID-19), and those without the infection.
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