Detection of IgM and IgG antibodies in patients with COVID-19 disease
Keywords:
COVID-19, immunoglobulin G, immunoglobulin M, SARS-CoV-2Abstract
The present study was planned to estimate some parameters linked covid 19 in Iraqi patients and these parameters includes serum levels of immunoglobulins (IgM and IgG) in the serum of the patients and comparing it with the healthy control group. This study aimed to determine the IgM and IgG responses against severe acute respiratory syndrome coronavirus (SARS-CoV)-2 in coronavirus disease 2019 (COVID-19) patients with varying illness severities. The study was conducted between 66 adult patients with COVID‐19 and compared with 22 age and gender-matched healthy subjects as controls. All patients were diagnosed and confirmed to be positive for COVID-19 by Real Time-Polymerase Chain Reaction (RT-PCR). , the blood samples have been collected from patients in Al-Zahraa teaching hospital and martyr fairus hospital and some private laboratories, with diagnosis of COVID-19 , from October 2021 - January 2022. The age range in both groups was 14–72 years. The patients were classified into mild group (22 patients),moderates group (22 patient), and severe group (22 patients). Serum samples were collected from all participants and tested for the immunoglobulines levels by ELISA (enzyme-linked immunosorbent assay) method.
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