Physicochemical evaluation of Solanum nigrum linn. and Tribulus terrestris linn.
Keywords:
Tribulus terrestris, Solanum nigrum, authentication, physicochemical propertiesAbstract
Herbal drugs are an integral part Indian medicinal system. Among them two plants are extensively used in folklore medicine system viz. Tribulus terrestris and Solanum nigrum because of numerous pharmacological activities. Various species of these plants are available, out of which some species are more potent whereas others have very less pharmacological potential. Therefore, identification of appropriate plant species is very important in the process of drug discovery and development. In the present study various physicochemical parameters were employed to identify powdered samples of fruit of Tribulus terrestris and berries of Solanum nigrum. These parameters include colour, odour, and taste. The physicochemical parameters evaluated for Tribulus terrestris and Solanum nigrum were found as moisture content (4.81, 6.89 respectively), loss on drying (5.16, 11.18 respectively) total ash values (7.44, 9.21 respectively) water soluble ash (4.081, 6.89 respectively), acid insoluble ash (0.81, 0.58) bulk density (0.50, 0.71) and tapped density (0.42, 0.65). The preliminary estimation of phytoconstituents were done by using TLC with different solvent systems and the Rf values were compared with standard. The ????max obtained for Tribulus terrestris and Solanum nigrum was found to be 201nm and 267 nm respectively.
Downloads
References
Annan K, Houghton PJ (2008), “Antibacterial, antioxidant and fibroblast growth stimulation of aqueous extracts of Ficus asperifolia Miq. and Gossypium arboreum L”, Journal of Ethnopharmacology .141-144.
Atanu U, Ebiloma, Ajayi EI, (2010) “A Review of the Pharmacological Aspects of Solanum nigrum Linn”.
Bijauliya, R.K., Alok, S., Chanchal, D.K. and Kumar, M (2017). “A comprehensive review on Standardization of Herbal Drugs”,International Journal of Pharmaceutical Sciences and Research, vol 8 no.9,pp. 3663-3667.
Biotechnology and molecular Biology Review vol 6, pp.1-7.
Chase CR, Pratt R (1948), “Fluorescence of powdered vegetable drug with particular reference to development of a system of identification”, Journal of American Pharmaceutical Association 38, 324-331.
Chhatre S, Nesari T, Somani G, Kanchan D, Sathaye S. (2014) Phytopharmacological overview of Tribulus terrestris. Pharmacogn Rev.8(15):45-51. doi: 10.4103/0973-7847.125530.
Gitu Pandey, Brahmeshwar Mishra (2013), “A New Analytical Q-Absorbance Ratio Method Development and Validation for Simultaneous Estimation of Lamivudine and Isoniazid”, Hindawi Publishing Corporation ISRN Spectroscopy. 1-5.
Gupta MM, Sharma RK, (1996) “Combined thin-layer chromatography densitometry method for quantitative determination of alkaloids of poppy straw samples”, Indian J. Pharm. Sci., 161–164.
Indhumathi.T, Dr. S. Mohandass (2013), “Identification of bioactive compounds in Solanum incanum fruit by Thin layer Chromatography and HPTLC”, International journal of Scientific Research, 2(6), 1-4.
Indian Herbal Pharmacopoeia, Indian Drug Manufacturers’ Association. Revised ed. (2002). 493–4
Jenkins, G.I, Kenevel, A.M, and Degage, F.E. (2008), “Quantitative Pharmaceutical Chemistry”, CBS Publishers & Distributors PVT. LTD., Daryaganj, New Delhi, Edn 6, 229-230, 239-242.
Khandelwal K. R, (2002) “Practical Pharmacognosy, Technique and Experiments”, Nirali Prakashan, Ninth Edition, 23.10-23.11 and 25.1-25.6.
Lachman L, Liberman HA, Kanig JL (1991),”The Theory and Practice of Industrial Pharmacy” Mumbai: Varghese Publishing House, 3rd ed. 67.
Mukharjee PK (2008)., “Quality Control of Herbal Drugs”, New Delhi: Business Horizons Pharmaceutical Publishers, 186,189.
Perveen S, Wadud A, Ahmed Makbul SA, Sofi G, Perveen (2019) A. Unani concept of drug substitution (therapeutic interchange) and its validation on scientific parameters. J Ayurveda Integr Med. doi: 10.1016/j.jaim.2017.11.006.
Rajani M, Kanaki NS (2008), “Phytochemical Standardization of Herbal Drugs and Polyherbal Formulations, Bioactive Molecules and Medicinal Plants”. Berlin, Heidelberg: Springer. 349–69.
Raskin I, Ribnicky DM, Komarnytsky S, Ilic N, Poulev A, Borisjuk N, Brinker A, Moreno DA, Ripoll C, Yakoby N, O'Neal JM, Cornwell T, Pastor I, Fridlender B (2002). Plants and human health in the twenty-first century. Trends Biotechnol. 20(12):522-31. doi: 10.1016/s0167-7799(02)02080-2. PMID: 12443874.
Rauf A, Waseem M , Rehman S. (2019) Physicochemical Standardization and Safety Evaluation of Khar-e-Khasak Khurd (Fruits of Tribulus terrestris): A Unani Drug. J Pharmacovig Drug Safety. 16(1):16-21.
Romana Rashid, Dr. Ghulam Nabi Hajam, Muzaffer Hussain Wani, Dr. Manik Sharma(2017). Organoleptic evaluation of the plant Solanum nigrum L. of the family Solanaceae. International Journal of Applied Research, vol 3(11) 142-145.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938
Toshiyuki Osakai (2017), “The Principle of Water-Content Determination by Karl Fischer Titration”. Review of Polarography, vol 63.101-107.
White PJ, Brown PH.(2010) Plant nutrition for sustainable development and global health. Ann Bot. 2010 Jun; 105(7):1073-80. doi: 10.1093/aob/mcq085. .
William Omuketi Emitaro, David Mutisya Musyimi, Darius Andika Otiato, Benson Onyango. 2017 Morphological, biochemical and molecular characterization of Xanthomonas campestris pv. vesicatoria of African nightshades (Solanum scabrum Mill.). Int. J. Biosci. 11(1), 190-197
Zafar R, Lawani M (1989), “Tribulus terrestris Linn. - A review of current knowledge”, Indian Drugs, 27(3).148-158.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.