A cross sectional observational study of cardiovascular response after propofol and etomidate anaesthesia induction

Sachin Kumbhare; Yogesh Tilkar; Ritesh Churihar; Sachin Parmar

doi:10.53730/ijhs.v6nS6.10974

Authors

Sachin Kumbhare Assistant Professor, Department of Anaesthesia, Government Medical College, Ratlam M.P.
Yogesh Tilkar Associate Professor, Department of Anaesthesia, Government Medical College Ratlam M.P
Ritesh Churihar Assistant Professor, Pharmacology Department, Government Medical College, Ratlam M.P.
Sachin Parmar
dr.sachinparmar@gmail.com
Assistant Professor, Department of Community Medicine, N.S.C Government Medical College, Khandwa, M.P.

Keywords:

cardiovascular response, etomidate, hemodynamic changes, laryngoscopy, propofol

Abstract

Etomidate and propofol are two common anaesthetic drugs. Etomidate can be used in patients with little hemodynamic reserve, whereas Propofol can result in more hemodynamic instability, according to prior research. During the induction of anaesthesia with Etomidate or, as a comparison, Propofol in elective surgeries, the cardiovascular response was examined in this study. Patients who were admitted for elective surgeries and ranged in age from 18 to 60 were included in this cross-sectional observational study. The cardiovascular responses of 50 (47) patients were assessed prior to induction, after the induction of anaesthesia with drugs, and at 1, 3, 5, and 10 minutes following the laryngoscopy. These measurements included systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), and O2 saturation (O2 sat). In terms of patient gender, age, and weight, there were no statistically significant differences between the two groups. At different times, changes in groups I and II's SBP, DBP, MAP, and HR were statistically significant. There were no discernible differences between groups I and II in terms of O2 saturation. Conclusion: Because Etomidate-treated patients have improved hemodynamic stability, it may be preferable to Propofol for general anaesthesia in the absence of contraindications.

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