A study to identify and isolate the most common organism causing Chronic suppurative otitis media (CSOM) in patients attending ENT OPD/IPD of tertiary care hospital
Keywords:
gram positive, gram negative, CSOM, culture, agarAbstract
Background: Chronic suppurative otitis media (CSOM) is a notorious infection and a major health problem in developing countries causing serious local damage and threatening complications. Early and effective treatment based on the knowledge of causative micro-organisms to ensures prompt clinical recovery and possible complications can thus be avoided.
Objective: The of this study was to isolate the organisms associated with CSOM. Materials and Methods: The prospective study was carried out at a tertiary care hospital in a time period of 1 yr (data collection) clinically diagnosed CSOM cases were included in the study.Pus samples from both outpatient and inpatient departments were included.Detailed history was obtained from each patient according to the case proforma. Result: Out of 122 pus samples significant growth was seen in 120(98.36%) samples, were 2(1.63%) sample showed insignificant or no growth. It is mostly seen that aerobic gram negative rods outnumber gram positive cocci organisms in CSOM as reported by some authors 175 which is comparable to the findings in the present study where gram negative rods accounted for 94(78.33%) and gram positive cocci 26(21.66%). Conclusion: Klebsiella pneumoniae (24.16%) was the commonest isolate followed by Pseudomonas aeruginosa (18.33%).
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Chronic suppurative otitis media–World Health Organization.www.who.int/pbd/publications/chronicsuppurativeotitis_media.pdf 2004.
Daly K, Hunter L, Levine S, Lindgren B, Giebink G. Relationships between otitis media sequelae and age. Laryngoscope. 1998;108:1306-1310..
Teele DW, Klein JO, Chase C, Menyuk P, The Greater Boston Otitis Media Study Group. Otitis Media in infancy and intellectual ability, school achievement, speech and language at age 7 years. J Infect Dis., 1990, 162: 658-694
Bennett KE, Haggard MP. Accumulation of factors influencing children's middle ear disease: risk factor modeling on a large population cohort. Journal of Epidemiology and Community Health. 1998;52:786-93
Yuceturk AV, Tack J. The evaluation of Eustachian tube functions in patients with COM. Clinical Otolaryngology. 1997; 22: 449-52
Sheahan P, Blanley AW. Sequelae of otitis media with effusion among children with cleft lip and/ or cleft palate. Clinical Otolaryngology. 2002; 27: 494-500
Fara M, Dvorak J. Abnormal anatomy of the muscles of palatopharyngeal closure in cleft palates: anatomical and surgical considerations based on the autopsies of 18 unoperated cleft palates. Plastic and Reconstructive Surgery. 1970; 46: 488-97
Roland PS. Chronic otitis media: a clinical overview. Ear Nose Throat J 2002; 81: 8
Verhoeff M, et al. Chronic otitis media: a review. Int J Pediatr Otorhinol 2006; 70-71
Vartiainen E, Vartiainen J. Effect of aerobic bacteriology on the clinical presentation and treatment results of COM. J Laryngol Otol 1996; 110: 315
Brook I, Burke P. The management of acute, serous and COM: the role of anaerobic bacteria. J Hosp Infect 1992; 22 Suppl A: 75
Brook I. The role of anaerobic bacteria in otitis media: microbiology, pathogens-is, and implications on therapy. Am J Otolaryngol 1987; 8: 109
Barobby GW, Zadik P. Bacteriology of otitis media in Ghana. Tropical Doctor, 1987, 17: 91-9224
Mawson S, Pollack M. Special role of Pseudomonas aeruginosa in chronic otitis media. Ann Otol Rhinol Laryngol Head and Neck Surg., 1988, 97 (9) (Suppl.130): 10-13
Kenna M. Incidence and prevalence of complications of otitis media. Ann Otol Rhinol Laryngol.,1990, 99 (7) (Suppl.149): 38-39
David S. Haynes. Peril-operative antibiotics in chronic otitis media. Ear, Nose and Throat Journal, August, 2002
Constanble L, Butler I. Microbial flora in chronic otitis media. J Infect 1982; 5: 57-60
Iquibal SM, Hassan A, Shafiq M. Chronic otitis media: disease pattern and drug sensitivity. J Surg Pak 2006; 11: 17-19
Park DC, Lee SK. Antimicrobial resistance of Staphylococcus from Otorrhoea in chronic otitis media and comparison with results of all isolated Staphylococci. Eur J Clin Microbiol Infect Dis 2008; 27: 571
(Collee JG, Duguid JP, Fraser AG, Marmion BP, Simmons A. Laboratory strategy in the diagnosis of infective syndromes. In Collee JG.Fraser AG, Microbiology, 14th Ed, Churchill Livingstone, Delhi,2007,p 53-94
Hopprich P.Lab of clinical Med 1960; 56: 899
Haynes DS, Rutka J, Hawke M, Roland PS. Ototoxicity of ototopical drops--an update. OtolaryngolClin North Am 2007; 40:669.
Yan JJ, Ko WC, Jung YC, Chuang CL, Wu JJ. Emergence of Klebsiella pneumoniae isolates producing inducible DHA-1 beta-lactamase in a university hospital in Taiwan. J Clin Microbiol 2002; 40:3121-6
Burke V. Notes on the gram stain with new method., P. Vol. Vii,no.2:p159-82
Poorley VK and Lyer A. Study of bacterial flora in chronic otitis media and its clinicalsignificance. Indian J Otolaryngol Head and Neck Surg 2002;54:91-5
Mansoor T, Mussani MA, Khalid G, Kumal M. Pseudomonas aeruginosa in ChronicOtitis media: sensitivity spectrum against various antibiotics in Karachi. J Ayub MedColl Abbottabad 2009; 21(2):120-23
Shyamla R, Reddy SP. The study of bacteriological agents of chronic otitis media-aerobic culture and evaluation. J Microbiol Biotechnol Res. 2012; (2):152-62
Mwaniki RK. Evaluation of bacterial flora and antimicrobial susceptibility of chronic
Aduda D, Macharia I, Mugwe P, et al. Bacteriology of chronic suppurative otitis media (CSOM) in children in Garissa district, Kenya: a point prevalence study. Int J PediatrOtorhinolaryngol. 2013;77:1107-1111.
Muluye D, Wondimeneh Y, Ferede G, Moges F, Nega T. Bacterial isolates and drug susceptibility patterns of ear discharge from patients with ear infection at Gondar University Hospital, Northwest Ethiopia. BMC Ear Nose Throat Disord. 2013;13:10
Shrestha BL, Amatya RC, Ghosh I. Microbiological Profile of Chronic otitis media.Nepalese J. of ENT Head and Neck Surgery, vol.2 No.2 Issue 2 (July- Dec 2011)
Kumar H, Seth S. Bacterial and Fungal study of 100 cases of Chronic otitis media. JClin Diag Res.2011;5:1224-7
Oguntibeju OO. Bacterial isolates from patients with ear infection. Indian Journal of Medical Microbiology. 2003; 21(4):294-5
Adoga A, Nimkur T, Silas O. Chronic suppurative otitis media: Socio-economic implications in a tertiary hospital in Northern Nigeria. Pan Afr Med J 2010; 4:3.
Kamal N, Joarder AH, Chowdhury AA, Khan AW. Prevalence of chronic suppurative otitis media among the children living in two selected slums of Dhaka City. Bangladesh Med Res Counc Bull 2004; 30:95.
Vartiainen E., Vartiainen J., Effects of aerobic bacteriology on clinical presentation and treatment results of COM Journal Laryngology and Otology 1996 April, 110(4):315-8.
Chirwa M. Microbiology of Chronic Otitis Media at Queen Elizabeth Central Hospital, Blantyre Malawi [dissertation]. Nairobi, Kenya: University Of Nairobi; 2014.
Hatcher J, Smith A, Mackenzie I, et al. A prevalence study of ear problems in school children in Kiambu district, Kenya. Int J Pediatr Otorhinolaryngol. 1995;33:19.
Van-der-Veen E, Schilder A, Van-Heerbeek N, et al. Predictors of Chronic Suppurative Otitis Media in Children. Arch Otolaryngol Head Neck Surg. 2006;132:1115-1118.
P.K Maji T.K. Chatterjee S. Chatterjee J. Chakrabarty B.B. Mukhopadhyay Ab Indian J. Otolaryngol. Head Neck Surg. 128 (April-June 2007) 59, 128-131
Hawkey p. Proteus, Providencia and Morganella spp. In: Gillespie S, Hawkey P, ed. Principles and Practice of Clinical Bacteriology. 2nd ed. West Sussex: John Wiley and sons; 2006:392-396
Koch A, Homøe P, Pipper C, et al. Chronic suppurative otitis media in a birth cohort of children in Greenland: population-based study of incidence and risk factors. Pediatr Infect Dis J 2011; 30:25.
Rawat V, Singhai M, Verma PK. Detection of beta-lactamases and their co-existence by using various disc combination methods in clinical isolates of Enterobacteriaceae and Pseudomonas species. J Lab Physicians. 2013; 5(1): 21-5.
David L. Paterson and o RbertClinicaBlMic A. onomo. robiology Extended—sReviewsp2005 Vol lactamases:V lactamases: A clinical update, ; 18 (4):657-686.
Brown DF, Andrews J, King A, and MacGowan AR extended-spectrum beta-lactarnases with E test and doubleisc potentiation methods. J. Antimicrob. Chemother 2000; 46:327-328.
Cormican MG, Marshall SA, and Jones RN. Detection of extended-spectrum betalactarnase (ESBL)-producing strains by the E test ESBL screen. J. Clin. Microbial 1996; 34:1880-1884.
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