A review on adverse drug reactions induced by anti-tuberculor drugs

Mudit Kumar; Pushpendra Kumar; Vikash Chandra; Mayank K. Choudhary; Navneet Kumar Verma

doi:10.53730/ijhs.v6nS4.11418

Authors

Mudit Kumar Assistant Professor, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences Saifai, Etawah U.P. India
Pushpendra Kumar Assistant Professor, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences Saifai, Etawah U.P. India
Vikash Chandra
vikashpharma2010@gmail.com
Assistant Professor, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences Saifai, Etawah U.P. India
Mayank K. Choudhary Student, Bachelor of Pharmacy, Uttar Pradesh University of Medical Sciences Saifai, Etawah U.P. India
Navneet Kumar Verma Assistant Professor, Buddha Institute of Pharmacy, GIDA, Gorakhpur, U.P, India

Keywords:

adverse drug reactions, anti-tuberculor drugs, Bacillus Mycobacterium

Abstract

Introduction: Tuberculosis is a chronic, highly contagious disease caused by the Bacillus Mycobacterium tuberculosis and spreads from person to person through air. Tuberculosis affects lungs majorly but also affects other parts of the body, such as brain, intestine, spine and kidney. The main cause for patient’s non-adherence to anti-tuberculosis therapy is ADRs of varying degrees of severity such as hepatotoxicity etc. Aim: This study aimed to provide proper understanding of Adverse drug reactions resulted due to Anti-TB drug therapy in TB patients based on various studies done on Anti-TB agents induced ADRs. Conclusion:Anti- Tuberculosisdrug (Anti-TB)could cause several ADRs both mild and severe types majority of ADR were wild, more attention is needed to prevent ADR and enhance current Anti-TB therapy. The study suggests that for more better in depth understanding and prevention of Anti-TB drug ADR many more studies with larger population is needed, also the current Anti-TB therapy requires some revisionto prevent fatal hepatotoxicity.

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