Efficacy of biosynthetically developed selenium nanoparticles using plant extracts of clove and cardamom

https://doi.org/10.53730/ijhs.v6nS5.11552

Authors

  • S. Abirami Post graduate, Department of Orthodontics and Dentofacial Orthopaedics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai
  • Ashwin Mathew George Professor, Department of Orthodontics and Dentofacial Orthopaedics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai
  • S Rajeshkumar Professor, Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science Saveetha University, Chennai, India

Keywords:

clove and cardamom, Selenium nanoparticles, antibacterial, anti inflammatory, cytotoxicity, TEM

Abstract

Background: The green approachable metal nanoparticles are treated to be an eco-friendly path and cost-effectiveness. In this present study, nano selenium was synthesized profitably by clove and cardamom. Methods:  Green synthesis of selenium nanoparticles was preliminarily confirmed by color changing from dark orange to red color in the reaction mixture. The resulting constructed nanoparticles were characterized by using ultraviolet spectroscopy absorbance around 450 nm. Characterization using HRTEM (High Resolution- Transmission Electron Microscope) to identify its size and shape. The organisms used to assess the antimicrobial efficacy of clove and cardamom reinforced selenium nanoparticles were Streptococcus mutans, Staphylococcus aureus and lactobacillus species and Candida albicans using Agar well diffusion method at 25 µL, 50 µL and 100 µL. In addition, we have analyzed its anti-inflammatory and cytotoxicity activity. Results:  UV-VIS spectroscopic analysis which showed a peak at 450 nm of the visible spectrum by reduction of selenium salts to Se NP’s. TEM spherical shape was of size 5 -20 nm. Good antimicrobial activity was noted against Streptococcus mutans, Staphylococcus aureus, and Lactobacillus species and Candida albicans. The mean zone of inhibition was found to be increased as the concentrations of Se NPs increased.

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Published

05-08-2022

How to Cite

Abirami, S., George, A. M., & Rajeshkumar, S. (2022). Efficacy of biosynthetically developed selenium nanoparticles using plant extracts of clove and cardamom. International Journal of Health Sciences, 6(S5), 9799–6811. https://doi.org/10.53730/ijhs.v6nS5.11552

Issue

Section

Peer Review Articles