Clinical, histological and radiographic evaluation of bone healing after tooth extraction using autologous platelet rich fibrin and 1% alendronate gel before dental implant

Ahmed Hussein Gaber; Mohamed Fouad Abd-Allah Edrees; Ibrahim Mahmoud Mowafy; Safaa M Tohamy; Mohammed A. El-Salam; Khaled Mohamed Elrahawy; Mohamed Gomaa Khalil; Emad Alqalshy; Mohamed Abdelrahman Mohamed; Mohamed Refaat Omar

doi:10.53730/ijhs.v6nS4.12992

Authors

Ahmed Hussein Gaber
ahmed_gaber@azhar.edu.eg
Lecturer in Oral Pathology Department, Faculty of Dentistry, Al-Azhar University (Assiut Branch), Al-Azhar University (Assiut Branch)
Mohamed Fouad Abd-Allah Edrees Ass. Professor and Head of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology Department, Faculty of Dentistry, Al-Azhar University (Assiut Branch)
Ibrahim Mahmoud Mowafy Ass. Professor of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology Faculty of Dentistry, Al-Azhar University (Assiut Branch)
Safaa M Tohamy Ass. Professor in Oral and Maxillofacial Pathology Department, Faculty of Dentistry, Assiut University
Mohammed A. El-Salam Oral and Maxillofacial Pathology Department, Faculty of Dentistry, Assiut University
Khaled Mohamed Elrahawy Ass. Professor of Oral Pathology Department, Faculty of Dentistry, Al-Azhar University (Assiut Branch), Al-Azhar University (Assiut Branch)
Mohamed Gomaa Khalil Ass. Professor of Oral Pathology Department, Faculty of Dentistry, Al-Azhar University (Assiut Branch), Al-Azhar University (Assiut Branch)
Emad Alqalshy Lecturer in Oral and Dental Pathology Department, Faculty of Dental Medicine, Al-Azhar University, Cairo, Egypt
Mohamed Abdelrahman Mohamed Ass. Professor in Oral and Dental Pathology Department, Faculty of Dental Medicine, Al-Azhar University, Cairo, Egypt
Mohamed Refaat Omar Oral Surgery Department, Faculty of Dentistry, Deraya University

Keywords:

clinical, histological, radiographic evaluation, bone healing, tooth extraction, dental implant

Abstract

Purpose: The present study was performed to evaluate clinically, radiographically and histologically the effect of autologous platelet rich fibrin (PRF) and 1% alendronate (ALN) gel in alveolar ridge preservation after tooth extraction. Materials and method: In this study, thirty patients with teeth indicated for extraction were divided randomly into three groups: Group A: the patients received 1% ALN gel mixed with PRF as a grafting material for the extraction socket. Group B: the patients received PRF only and in Group C the socket left without any a grafting material. All patients were evaluated clinically and radiographically at; base line and after 3 months. Also, histological evaluation using bone core biopsy harvested at the re-entry surgery before implant placement. Results of the present study were recorded, tabulated and statistically analyzed. Results: Histological, clinical and radiographic findings showed a statistically significant difference in group A when compared to both group B and group C. Conclusions: The addition of ALN to PRF leaded to a noticeable socket preservation and reduction in the amount of bone resorption during the observation period of the study.

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