COVID-19 impact on hematological and biochemical parameters on outcomes of admitted patients
Keywords:
Hematological, Biochemical, COVID-19, Recovered, Death, Outcomes, PathologyAbstract
COVID-19 an ongoing pandemic has high transmission and mortality rate gets the attention of researchers to focus on the disease. The burden of disease on the health care system focuses on the COVID-19 impacts on the hematological and biochemical parameters. This study aimed to focus on the laboratory indicators that fluctuate in COVID-19. The single-center cross-sectional study in the pathology department of POF hospital Wah Cantt from August 2021 to December 2021. Three hundred positive COVID-19 patients were included in the study. About 138 (46%) were males and 162 (54%) females and the mean age was 58 ± 15.06 (range 5 – 86). The biochemical indicator raised in COVID-19 included CPK (191.25 ± 507.39), CRP (68.81 ± 70.95), LDH (429.48 ± 246.96), and ALT (46.50 ± 43.23). In hematological parameters, only neutrophils elevated (70.00 ± 13.52) lymphocytes decreased. Laboratory parameters measured were similar values in recovered and death cases. The findings suggest the raised level of CRP, LDH, CPK, ALT, ferritin, D-Dimer, and neutrophils predict early diagnosis and prompt treatment.
Downloads
References
Abid, K., Bari, Y. A., Younas, M., Tahir Javaid, S. and Imran, A. J. A. P. J. o. P. H. (2020) 'Progress of COVID-19 Epidemic in Pakistan', 32(4), pp. 154-156.
Ahnach, M., Zbiri, S., Nejjari, S., Ousti, F. and Elkettani, C. J. J. o. m. b. (2020) 'C-reactive protein as an early predictor of COVID-19 severity', 39(4), pp. 500.
Bogiel, T., Rzepka, M. and Depka, D. J. D. (2021) 'Reliable Diagnostics of SARS-CoV-2 Infections Using One-and Two-Gene Molecular Tests for a Viral RNA Detection—Results Questioning Previous Observations', 11(10), pp. 1839.
Carter LJ, G. L., Smoot JW, Li Y, Zhou Q, Saveson CJ, Sasso JM, Gregg AC, Soares DJ, Beskid TR, Jervey SR, Liu C. (2020, May) 'Assay Techniques and Test Development for COVID-19 Diagnosis. ', ACS Cent Sci. Epub, 27;6(5)( PMID: 32382657; ), pp. 591-605. DOI: doi: 10.1021/acscentsci.0c00501.
Chughtai, A. and Malik, A. J. G. B. (2020) 'Is Coronavirus disease (COVID-19) case fatality ratio underestimated?', 2(1).
Fan, B. E. J. A. j. o. h. (2020) 'Hematologic parameters in patients with COVID-19 infection: a reply', 95(8), pp. E215-E215.
Fong, S. J., Dey, N. and Chaki, J. (2021) Artificial intelligence for coronavirus outbreak. Springer.
Gennaro, F. D. J. I. J. o. E. R. and Health, P. (2020) 'Damiano Pizzol at all. 2020. Coronavirus Diseases (Covid 19) Current Status and Future Perspectivees: A Narative Review', 2690.
Javadi, A., Dabiri, S., Meymandi, M. S., Bahremani, M. H., Soleimantabar, H., Dabiri, B., Vosough, H., Sharan, M. G. and Sedaghati, F. J. I. J. o. P. (2022) 'Changes of Routine Hematological Parameters in COVID-19 Patients: Correlation with Imaging Findings, RT-PCR and Outcome', 17(1), pp. 37.
Katipoğlu, B., Sönmez, L. Ö., Vatansev, H., Yüce, N., Sabak, M., Szarpak, L., Evrin, T. J. D. and Journal, E. M. (2020) 'Can hematological and biochemical parameters fasten the diagnosis of COVID-19 in emergency departments?', 5(4), pp. 175-181.
Khalid, A., Ali Jaffar, M., Khan, T., Abbas Lail, R., Ali, S., Aktas, G., Waris, A., Javaid, A., Ijaz, N. and Muhammad, N. J. H. (2021) 'Hematological and biochemical parameters as diagnostic and prognostic markers in SARS-COV-2 infected patients of Pakistan: a retrospective comparative analysis', 26(1), pp. 529-542.
Lei, J., Li, J., Li, X. and Qi, X. J. R. (2020) 'CT imaging of the 2019 novel coronavirus (2019-nCoV) pneumonia', 295(1), pp. 18-18.
Najim, R. H. J. S. R. i. P. (2020) 'Biochemical and hematological parameters as a predictor for COVID-19 infection in 65 patients diagnosed by real time? PCR in Kirkuk city', 11(5), pp. 797-799.
Noreen, N., Naveed, I., Dil, S., Niazi, S., Saleem, S., Mohiuddin, N., Khan, N., Noor, B., Khan, M. and Khan, F. J. G. B. (2020) 'Trend Analysis of exponential increase of Covid-19 cases in Pakistan: An interpretation', 2(1).
Rutledge, A. C., Choi, Y.-H., Karp, I., Bhayana, V. and Stevic, I. J. C. b. (2021) 'Biochemistry tests in hospitalized COVID-19 patients: Experience from a Canadian tertiary care centre', 95, pp. 41-48.
Saddique, A., Adnan, S., Bokhari, H., Azam, A., Rana, M. S., Khan, M. M., Hanif, M., Sharif, S. J. E. S. and Environment (2021) 'Prevalence and associated risk factor of COVID-19 and impacts of meteorological and social variables on its propagation in Punjab, Pakistan', 5(3), pp. 785-798.
Siripanthong, B., Nazarian, S., Muser, D., Deo, R., Santangeli, P., Khanji, M. Y., Cooper Jr, L. T. and Chahal, C. A. A. J. H. r. (2020) 'Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management', 17(9), pp. 1463-1471.
Sobhani, S., Aryan, R., Kalantari, E., Soltani, S., Malek, N., Pirzadeh, P., Yarahmadi, A. and Aghaee, A. J. I. p. o. i. d. (2021) 'Association between clinical characteristics and laboratory findings with outcome of hospitalized COVID-19 patients: a report from Northeast Iran', 2021.
Waris, A., Din, M., Khalid, A., Abbas Lail, R., Shaheen, A., Khan, N., Nawaz, M., Baset, A., Ahmad, I. and Ali, M. J. J. o. C. L. A. (2021) 'Evaluation of hematological parameters as an indicator of disease severity in Covid‐19 patients: Pakistan's experience', 35(6), pp. e23809.
Wu, Z. and McGoogan, J. M. J. j. (2020) 'Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention', 323(13), pp. 1239-1242.
Xavier, A. R., Silva, J. S., Almeida, J. P. C., Conceição, J. F. F., Lacerda, G. S. and Kanaan, S. J. J. B. d. P. e. M. L. (2020) 'COVID-19: clinical and laboratory manifestations in novel coronavirus infection', 56.
Zhang, D., Zhou, X., Yan, S., Tian, R., Su, L., Ding, X., Xiao, M., Chen, Y., Zhao, H. and Chen, H. J. C. C. A. (2020) 'Correlation between cytokines and coagulation-related parameters in patients with coronavirus disease 2019 admitted to ICU', 510, pp. 47-53.
Published
How to Cite
Issue
Section
Copyright (c) 2023 International journal of health sciences
![Creative Commons License](http://i.creativecommons.org/l/by-nc-nd/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.