Seroprevalence of anti-SARS-CoV-2 total antibodies among COVID-19 patients in province of Punjab, Pakistan

Adil Abbas; Muhammad Wajahat; Murat Sayan; Sidra Noureen; Ramsha Shoaib; Aleena Ahmad Khan; Ayse Arikan

doi:10.53730/ijhs.v6nS8.13945

Authors

Adil Abbas
aadillkhan1995@gmail.com
Faculty of Medicine, Department of Medical Microbiology and Clinical Microbiology, Near East University, Nicosia, Northern Cyprus
Muhammad Wajahat MPhil Scholar, Department of Microbiology, University of Haripur, Pakistan/ Laboratory Technologist, POF Hospital, Pakistan
Murat Sayan Kocaeli University, Faculty of Medicine, Clinical Laboratory, PCR Unit, Kocaeli, Turkey & DESAM Research Institute, Near East University, Nicosia, Northern Cyprus
Sidra Noureen PhD Scholar, Department of Microbiology and Molecular Genetics, The Women University, Multan, 66000, Pakistan
Ramsha Shoaib PhD Scholar, Department of Molecular Biology, Virtual University of Pakistan
Aleena Ahmad Khan PhD Scholar, Department of Molecular Biology, Virtual University of Pakistan
Ayse Arikan Faculty of Medicine, Department of Medical Microbiology and Clinical Microbiology, Near East University, Nicosia, Northern Cyprus & Kocaeli University, Faculty of Medicine, Clinical Laboratory, PCR Unit, Kocaeli, Turkey

Keywords:

COVID-19, SARS-CoV-2, ELISA, antibody testing

Abstract

At the end of 2019, there was an outbreak of coronavirus in Wuhan, China which killed more than 1800 people and more than 70,000 people were infected during the first 5 days. Chinese researchers named it as a novel coronavirus disease 2019. Up to now, 231 million cases and more than 4 million deaths have been reported worldwide. The total number of cases of COVID cases in Pakistan was 1,236,888 so far and the total death toll was 27,500 and is increasing rapidly. OmniPATHTM COVID-19 Total Antibody ELISA Test kit was used for serological analysis. We found that the highest number of patients with positive antibody test was Lahore with 48%. (n=442). Total antibodies against SARS-CoV-2 was found to be higher in men (43%) compared to women (41%). 13% of the children were found to be positive for SARS-CoV-2 IgG. In age wise distribution, patients in age group 41-50 year were recorded highest seroprevalance. We took the mean of antibody titer according to different age groups and we found the highest mean of antibody titer which was 171 in age group (21-30).

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