Comparison of lipid profiles and hypertension in type 02 diabetes mellitus patients with and without hypertension a multi center study
Keywords:
type 02 diabetes mellitus, dyslipidemia, hypertensionAbstract
Introduction: Persistent hyperglycemia and anomalies in the metabolism of proteins, lipids, and carbohydrates are hallmarks of diabetes mellitus, which is brought on by insufficient insulin synthesis or action. Other associated systemic problems, such dyslipidemia and hypertension, may result from this. Dyslipidemia increases cardiovascular events such persistent high blood pressure by raising serum triglycerides, free fatty acids, and HDL cholesterol and lowering it. This research examined hyperlipidemia. Type 2 diabetics, regardless of hypertension. Objective: to compare T2DM with and without hypertension, the present study evaluated the blood lipid profiles of both groups. Layout of the study An experimental research approach is used, along with a comparative study methodology. Methodology: the multi-center study conducted in department of medicine HMC hospital Peshawar OPDs and Out Door Patients hosted the research. From January 2021 to January 2022, performed lab tests. The Multi center study achieved our aim. The study comprised 100 type 2 diabetics divided into cases and controls. Cases had type 02 diabetes and hypertension, but controls did not. Both groups estimated cholesterol, triglycerides, LDL, and HDL levels. The statistical analysis uses SPSS version 28. Mean values and an independent student T-test were used to compare groups.
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American Diabetes Association. Standards of Medical Care in Diabetes—2019. Diabetes Care. 2019;42(Suppl.1):S1-S193.
Chandalia M, Garg A, Lutjohann D, et al. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med. 2000;342(19):1392-1398.
Denke MA. Effect of low-carbohydrate diets on plasma lipoprotein subfractions and particle size in type 2 diabetes mellitus. Metabolism. 2004;53(11):1523-1530.
Jia L, Zhang W, Wang P, et al. Association between lipid profile and hypertension in patients with type 2 diabetes: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2018;18(1):152.
Mhurchu CN, Poppitt SD, McGill AT, et al. Effect of dietary composition on postprandial lipemia in type 2 diabetes mellitus: a randomized controlled trial. Am J
Akbari, S., Khatami, M., Amiri, M., & Mahmoudi, M. (2019). Association of Lipid Profile and Hypertension in Patients with Type 2 Diabetes Mellitus: A Cross-sectional Study. Lipids in health and disease, 18(1), 1-9.
Littman, A., Smith, E., & Duker, P. (2013). Hypertension in type 2 diabetes. Diabetes Spectrum, 26(3), 155-162.
Shafiq, F., & Hashmi, S. (2016). Comparison of lipid profile in type 2 diabetes mellitus with and without hypertension. International journal of health sciences, 10(2), 125-128.
Stone, N. J., Robinson, J. G., Lichtenstein, A. H., Bairey Merz, C. N., Blum, C. B., Eckel, R. H., ... & Grundy, S. M. (2014). 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task
Cha YS, Jung CH, Kim MJ, et al. Lipid Profiles and Hypertension in Type 2 Diabetes Mellitus Patients with and without Coronary Artery Disease. Korean J Intern Med. 2018;33(2):313-321.
El-Kebbi IM, Ali T, Li B, et al. Diabetes, hypertension, and dyslipidemia: a review of current evidence. Curr Atheroscler Rep. 2018;20(5):25.
Al-Daghri NM, Al-Attas OS, Alokail MS, et al. Dyslipidemia in type 2 diabetes mellitus and its association with hypertension: a cross-sectional study. PLoS One. 2018;13(5):e0198091.
American Diabetes Association. Standards of Medical Care in Diabetes—2019. Diabetes Care. 2019;42(Suppl.1):S1-S193.
American Diabetes Association. Standards of Medical Care in Diabetes—2021. Diabetes Care. 2019;42(Suppl.1):S1-S202.
rmstrong, M. J., Gaunt, M. E., & Reid, J. L. (2008). Lipid profiles in type 2 diabetes: a systematic review and meta-analysis. Diabetes care, 31(3), 625-633.
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