Comparison of hematological parameters in anemia of chronic disease and chronic periodontitis
Keywords:
hematological parameters, anemia, chronic diseaseAbstract
Background: Periodontitis is a localized, chronic inflammatory reaction, induced by bacteria, and effect healthy periodontium. The third highest prevalence of periodontal disease in the world is in Asia.6 Infections, malignant cells, and autoimmune dysregulation these all factors lead to the activate the immune system and start production of cytokines. Chronic periodontitis can be a cause of anemia of chronic diseases. Materials and Methods: The study population consisted of 160 individuals between the age groups of 20-70 years, Hemoglobin concentration, Erythrocyte count, Mean corpuscular volume, Mean corpuscular hemoglobin, Mean corpuscular hemoglobin concentration was measured using an automated hematology analyser. ESR was estimated using Westergren’s method. Serum ferritin was measured on ELISA kit by a semi automated analyser on LISA SCAN. Students “t” test was used for comparing the mean Hb, erythrocyte count, MCV, MCH, MCHC, ESR, and ferritin between the two groups. Results: The comparison of blood parameters was done among study and control males. Mean value of hemoglobin, RBC, MCH, MCHC, ESR and Serum Ferritin were statistically significant(P<0.001) whereas mean value of MCV was statistically insignificant. The comparison of blood parameters was done among study and control females.
Downloads
References
Hatipoglu H, Hatipoglu GM, Cagirankaya Berna L., Caglayan F Severe periodontal destruction in a patient with advanced anemia: A case report European journal of dentistry 2012; 6:95-100.
Rath SK , Sen S , Gupta N, Mukesh, Roy SK. Porphyromonas gingivalis in coronary atheroma and subgingival plaque – a clinical and microbiological study. Journal of Evolution of Medical and Dental Sciences. 2014; 3: 03 .551-58
Teles R, Teles F , Lopez JF, Paster B, Haffajee A. Lessons learned and unlearned in periodontal microbiology. Periodontol 2000. 2013 Jun; 62(1): 95–162.
Agnihotram G, Mahesh Singh TR, Pamidimarri G, Jacob L, Rani S, Sravanthi study of clinical parameters in chronic periodontitis International Journal of Applied Biology and Pharmaceutical Technology Volume: I: Issue-3: Nov-Dec -2010
Kesic L Milasin J, Igic M, Obradovic R microbial etiology of periodontal disease – mini review Medicine and Biology Vol.15, No 1, 2008, pp. 1 – 6
Anumolu VN, Srikanth A, Paidi K. Evaluation of the relation between anemia and periodontitis by estimation of blood parameters: A cross-sectional study. J Indian Soc Periodontol 2016;20:265-72
Hutter JW, Van der Velden U, Varoufaki A, Huffels RAM, Hoek FJ, Loos BG. Lower number of erythrocytes and lower levels of hemoglobin in periodontitis patients compared to control subjects. J Clin Periodontol 2001; 28:930-936
Geoffrey BHIL. Anemia of chronic diseases.CME 2008:26:238-40
Means RT Jr., Krantz SB. Progress in understanding the pathogenesis of the anemia of chronic disease. Blood 1992;80:1639-47
Swaak A. Anemia of chronic disease in patients with rheumatoid arthritis: Aspects of prevalence, outcome, diagnosis, and the effect of treatment on disease activity. J Rheumatol 2006;33:1467-8.
Newman MG, Takei HH, Klokkevold PR, Carranza FA. 10th ed. Carranza’s Clinical Periodontology. Missouri. Elsevier,2006
Loos BG. Systemic markers of inflammation in periodontitis. J Periodontol 2005; 76(11 Suppl): 2106-2115.
Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005;352: 1011-1023.
Shah S, Anand PM, Acharya V, Bichila SK, Karnad D, Kamath S et.al. API text book of medicine. 7th ed. Association of physicians of India. Mumbai.
Seigel EH. Total erythrocyte, leukocyte and differential white cell counts of blood in chronic periodontal disease. J Dent Res 1965;24:270-271.
Agarwal N, Kumar VSC, Gujjari SA. Effect of periodontal therapy on hemoglobin and erythrocyte levels in chronic generalized periodontitis patients: An interventional study. J Ind Soc Periodontol 2009; 13(1):6-11.
Gokhale SR, Sumanth S, Padhye AM. Evaluation of blood parameters in patients with chronic periodontitis for signs of anemia. J Periodontol 2010;81:1202-1206.
Naik V, Acharya A, Deshmukh VL, Shetty S, Shirahatti R. Generalized severe chronic periodontitis is associated with anemia of chronic disease: a pilot study in urban Indian males. J Invest Clin Dent 2010; 139-143.
Yamamoto T, Tsuneishi M, Furuta M, Ekuni D, Morita M, Hirata Y. Relationship between decrease of erythrocyte count and progression of periodontal disease in rural Japanese population. J Periodontol 2011;82:106-113.
Wakai K, Kawamura T, Umemura O, Hara Y, Machida J, Anno T et.al. Associations of medical status and physical fitness with periodontal disease. J Clin Periodontol 1999;26:664-672
Havemose- Poulsen A, Westergaard J, Stoltze K, Skodt H, Danneskiold- Samsoe B, Locht H et.al. Periodontal and hematological characteristics associated with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. J Periodontol 2006;77:280-288.
Aljohani HA. Association between hemoglobin level and severity of chronic periodontitis. JKAU Med Sci. 2010;17 (1): 53-64.
Prathap S, Hegde S, Rajesh KS, Arun Kumar MS. Anemia- a risk factor for periodontitis. Kerala Dental journal 2010;33(3): 173-175.
Pradeep AR, Sharma A, Raju AP. Anemia of chronic diseases and chronic periodontitis: does periodontal therapy have an effect on anemic status? J Periodontol 2011;82:388-394..
Agnihotram G, Mahesh Singh TR, Pamidimarri G, Jacob L, Rani S, Sravanthi study of clinical parameters in chronic periodontitis International Journal of Applied Biology and Pharmaceutical Technology Volume: I: Issue-3: Nov-Dec -2010
Ali S The correlation between hemoglobin level and generalized moderate chronic periodontitis J Bagh College Dentistry Vol. 24(special issue 1), 2012
Kaur Harjit. Hematological Parameters -A Diagnostic Mirror For Periodontitis Indian Journal of Dental Sciences.2013:2:5, 45-48.
Rai B, Anand SC. After scaling and root planning lower systemic inflammatory and thrombotic markers of cardiovascular risk. Middle east J Scient Res 2007 (2): 54-56.
Erdemira EO, Nalcacib R, Caglayan O. Evaluation of Systemic Markers Related to Anemia of Chronic Disease in the Peripheral Blood of Smokers and Non-Smokers with Chronic Periodontitis. Eur J Dent. 2008; 2: 102-109
Shin-Yu Lu, Eng H L Dramatic recovery from severe anemia by resolution of severe periodontitis J Dent Sci 2010;5(1):41−46
Parashar K, Khera T, Somani R, Shukla P Co-relation between chronic periodontitis and anemia – A pilot study Indian Journal of Public Health Research & Development Year:2012,Volume:3,Issue:2
Prakash S, Dhingara K, Priya S Similar hematological and biochemical parameters among periodontitis and control group subjects Eur J Dent 2012;6:287-294
Goldstein H. Systemic and blood picture findings in several hundred periclasia- free and periclasia involved individuals. J Dent Res 1937;16:320.
Lainson PA, Brady PP, Fraleigh CM. Anemia, a systemic cause of periodontal disease? J Periodontol 1968;39:35-38.
Chawla TN, Kapoor KK, Teotia SPS, Singh NK. Anemia and periodontal disease: A correlative study. J Ind Dent Assoc 1971;43:67-78.
Moura C, Moraes G, Bittencourt M, Terezan M The influence of non-surgical periodontal treatment on white and red blood cells of patients with chronic periodontitis R. Periodontia - Março 2011 - Volume 21 - Número 01
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
