Comparison of hematological parameters in anemia of chronic disease and chronic periodontitis
Keywords:
hematological parameters, anemia, chronic diseaseAbstract
Background: Periodontitis is a localized, chronic inflammatory reaction, induced by bacteria, and effect healthy periodontium. The third highest prevalence of periodontal disease in the world is in Asia.6 Infections, malignant cells, and autoimmune dysregulation these all factors lead to the activate the immune system and start production of cytokines. Chronic periodontitis can be a cause of anemia of chronic diseases. Materials and Methods: The study population consisted of 160 individuals between the age groups of 20-70 years, Hemoglobin concentration, Erythrocyte count, Mean corpuscular volume, Mean corpuscular hemoglobin, Mean corpuscular hemoglobin concentration was measured using an automated hematology analyser. ESR was estimated using Westergren’s method. Serum ferritin was measured on ELISA kit by a semi automated analyser on LISA SCAN. Students “t” test was used for comparing the mean Hb, erythrocyte count, MCV, MCH, MCHC, ESR, and ferritin between the two groups. Results: The comparison of blood parameters was done among study and control males. Mean value of hemoglobin, RBC, MCH, MCHC, ESR and Serum Ferritin were statistically significant(P<0.001) whereas mean value of MCV was statistically insignificant. The comparison of blood parameters was done among study and control females.
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