Liver cirrhosis
The struggling liver
Keywords:
Liver cirrhosis, Child-Pugh-Turcotte (CPT), lipids, Hepatic EncephalopathyAbstract
Liver cirrhosis is a chronic liver infection. It consist of deterioration of liver cells along with fibrosis and infection generating nodules. Patients with cirrhosis frequently have either global malnutrition or alterations in specific aspects of nutritional status, such as micronutrient deficiencies, due to multiple mechanisms, including poor nutritional intake, poor absorption, and increased losses. In addition, one of the most significant nutritional problems in cirrhotic patients is muscle wasting and sarcopenia. Cirrhosis of the liver is more common than previously thought, affecting more than 633,000 adults yearly, according to a study published in the Journal of Clinical Gastroenterology. People with cirrhosis had a mortality rate of 26.4 percent during a two-year interval. Most common cause of the liver cirrhosis is alcohol intake (60 to 70 percent), biliary obstruction (5 to 10 percent), biliary atresia/neonatal hepatitis, chronic Hepatitis B or C (10 percent) and hemochromatosis (5 to 10 percent). Symptoms include jaundice, fatigue, bleeding or bruising easily, nausea, swelling and confusion. But many patients have no symptoms. Cirrhosis can lead to liver failure and liver cancer. Numerous studies have attempted to develop the Child-Pugh-Turcotte (CPT) classification for prognosis of liver cirrhosis. Major complications of cirrhosis are, Ascites, Upper gastrointestinal bleeding.
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Shashidhar KN and Krishna Sumanth Nallagangula. “Pros and Cons of Existing Biomarkers for Cirrhosis of Liver”. Acta Scientific Medical Sciences 3.6 (2019): 63-72
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