To determine the correlation of severity of thrombocytopenia, with vitamin B12 deficiency in patients of dengue fever
Keywords:
vitamin B12, dengue fever, severity thrombocytopeniaAbstract
Objective: To determine the correlation between the severity of thrombocytopenia, hospital stay, hematological, & biochemical parameter with vitamin B12 deficiency, &role of vitamin B12 supplementation in patients of dengue fever. Methodology: 100 dengue patient were included in the study. All baseline parameter were examined along with platelet count and vitamin B12 level. Results: platelets count and vitamin B12 were low in dengue patient and platelet count is positively correlated with vitamin b 12 level.(r=0.57, p value < 0.05). Conclusion: a significant positive correlation between the severity of thrombocytopenia &vitamin B12 deficiency was observed. Vitamin B12 supplementation improved the hematological and biochemical parameters also having a significant association with platelet recovery in the form of less requirement of random donor platelets transfusion.
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