To determine the correlation of severity of thrombocytopenia, with vitamin B12 deficiency in patients of dengue fever

Vidya Sagar; Manoj Kumar; Ramakant Rawat; Pankaj Kumar; Granth Kumar; Surjeet Kumar Yadav

doi:10.53730/ijhs.v6nS2.6379

Authors

Vidya Sagar Associate professor, Medicine department, UPUMS, SAIFAI, ETAWAH, Uttar Pradesh
Manoj Kumar Professor and Head of department Medicine, Department, UPUMS, Saifai, ETAWAH, Uttar Pradesh
Ramakant Rawat Associate professor, Medicine department, UPUMS, SAIFAI, ETAWAH, Uttar Pradesh
Pankaj Kumar
ns4090836@gmail.com
Assistant Professor, Medicine Department UPUMS, Saifai, ETAWAH, Uttar Pradesh
Granth Kumar Associate professor, Medicine department, UPUMS, SAIFAI, ETAWAH, Uttar Pradesh
Surjeet Kumar Yadav Junior resident, Medicine department, UPUMS, SAIFAI, ETAWAH, Uttar Pradesh

Keywords:

vitamin B12, dengue fever, severity thrombocytopenia

Abstract

Objective: To determine the correlation between the severity of thrombocytopenia, hospital stay, hematological, & biochemical parameter with vitamin B12 deficiency, &role of vitamin B12 supplementation in patients of dengue fever. Methodology: 100 dengue patient were included in the study. All baseline parameter were examined along with platelet count and vitamin B12 level. Results: platelets count and vitamin B12 were low in dengue patient and platelet count is positively correlated with vitamin b 12 level.(r=0.57, p value < 0.05). Conclusion: a significant positive correlation between the severity of thrombocytopenia &vitamin B12 deficiency was observed. Vitamin B12 supplementation improved the hematological and biochemical parameters also having a significant association with platelet recovery in the form of less requirement of random donor platelets transfusion.

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