The pattern of rheumatological disorders and its management in rural population of central India

Manoj Kumar; Ramakant Rawat; Sushil Kumar; Granth Kumar; SPS Gill; Ankit Kumar

doi:10.53730/ijhs.v6nS1.5611

Authors

Manoj Kumar Professor, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
Ramakant Rawat Associate Professor, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
Sushil Kumar Assistant Professor, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
Granth Kumar Associate Professor, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
SPS Gill Professor, Department of Orthopedics, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
Ankit Kumar Junior Resident, Department of Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India

Keywords:

rheumatological disorders, osteoarthritis, rheumatoid arthritis, inflammatory joint diseases

Abstract

Background: India is home to the world's second largest population. Rheumatology is an emerging specialty in India. We looked at publications in the field of rheumatology from India from over the past six years using Scopus and Medline databases. Despite rheumatologic disorders affecting 6.0%-24.0% of the population, rheumatology in India is still in its infancy. So, we studied the pattern of rheumatological disorders and its management in rural population of central India. Material and Methods: A cross sectional study was done for a period of 18 months on 100 people attending inpatient and outpatient from General Medicine and Orthopaedics departments of Uttar Pradesh University of Medical Sciences, Saifai, India. All patients of age 12 years and above coming to UPUMS with history suggestive of Rheumatological disorders were included in the study. Results: Out of 100 studied patients 85.0%were in age group 31-40 years with female predominance (72.0%). Hypertension was the commonest comorbidity followed by hypothyroidism and diabetes. Rheumatoid arthritis (49.0%) was the most common disease followed by Osteoarthritis (20.0%), Spondyloarthritis (18.0%) and Systemic lupus erythematosus (7.0%). The difference between joint examination in different rheumatic disease was statistically insignificant (p>0.05).

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References

Mittal G, Bisht M, Pai VS, Handu SS. Evaluation of prescription practices in rheumatoid arthritis at the rheumatology clinic in a tertiary care teaching hospital in Uttarakhand: A cross-sectional study. J Family Med Prim Care 2021;10:745-51

Kudial S, Tandon VR, Mahajan A. Rheumatological disorder (RD) in Indian women above 40 years of age: A cross-sectional WHO-ILAR-COPCORD-based survey. J Mid-life Health 2015;6:76-80.

Malaviya AN, Kapoor SK, Singh RR, Kumar A, Pande I. Prevalence of rheumatoid arthritis in the adult Indian population. Rheumatol Int. 1993;13:131–134.

Malaviya AN, Singh RR, Singh YN, Kapoor SK, Kumar A. Prevalence of systemic lupus erythematosus in India. Lupus. 1993;2:115–118.

Handa R. Rheumatology in India--quo vadis? Nat Rev Rheumatol. 2015;11:183–188.

Joshi VR, Bang AA, Bhojraj SY, et al. Clinical pattern and prevalence of rheumatic diseases among adults: a community-based cross-sectional study in rural Gadchiroli, India. Journal of Global Health Reports. 2021;5:e2021040.

Syngle A, Kaur S, Verma I, Syngle T, Syngle V. Cost-effective analysis of disease-modifying anti-rheumatic drugs in rheumatoid arthritis. Clin Rheumatol 2017;36:1715-20.

Mittal N, Mittal R, Sharma A, Jose V, Wanchu A, Singh S. Treatment failure with diseasemodifying antirheumatic drugs in rheumatoid arthritis patients. Singapore Med J 2012;53:532-6.

Singh P, Bharat S, Bano M, Gaur S, Srivastava B. Adverse drug reactions in rheumatoid arthritis patients taking combination DMARDs. J Med Sci Clin Res 2016;4:12115-24.

Jagdish RK, Bhatnagar MK, Malhotra A. Study of pattern of rheumatologic and musculoskeletal disorders and their awareness among patients attending rheumatology clinic. MOJ Orthop Rheumatol. 2018;10(2):139‒145. DOI: 10.15406/mojor.2018.10.00402

Cutolo M, Villaggio B, Seriolo B, Montagna P, Capellino S, Straub RH, et al. Synovial fluid estrogens in rheumatoid arthritis. Autoimmun Rev 2004;3:193-8.

Jebastine MI, Nasmi N, Elias N, NeethuVV, Arul B. Prescription pattern of drugs used in management of rheumatoid arthritis in a tertiary care hospital: A retrospective study. Indo Am J Pharm Sci 2015;2:1198-205.

Kudial S, Tandon VR, Mahajan A. Rheumatological disorder (RD) in Indian women above 40 years of age: A cross-sectional WHO-ILAR-COPCORD-based survey. J Midlife Health 2015;6:76-80.

Murdaca G, Colombo BM, Cagnati P, et al. Endothelial dysfunction in rheumatic autoimmune diseases. Atherosclerosis. 2012;224(2):309-17.

Ranwa BL et al. Prevalence of rheumatic diseases in urban bikaner population in western rajasthan: A WHO-ILAR COPCORD STUDY. International Journal of Basic and Applied Medical Sciences. 2012;2(1):138-145.

Miedema HS, van der Linden SM, Rasker JJ, et al. National database of patients visiting rheumatologists in the Netherlands : the standard diagnosis register of rheumatic diseases. A report and preliminary analysis. Br J Rheumatol. 1998;37:555–61.

Zink A, Listing J, Klindworth C, Zeidler H, for the German Collaborative Arthritis Centres. The national database of the German Collaborative Arthritis Centres: I. Structure, aims and patients. Ann Rheum Dis 2001;60:199–206.

Vanhoof JK, Declerck P Geusens. Prevalence of rheumatic diseases in a rheumatological outpatient practice. Ann Rheum Dis 2002;61:453–455.

Singh JA, Saag KG, Bridges SL Jr, Akl EA, Bannuru RR, Sullivan MC, et al. 2015 American college of rheumatology guideline for the treatment of rheumatoid arthritis. Arthritis Rheumatol 2016;68:1-26

Kavanaugh A. Economic issues with new rheumatologic therapeutics. Curr Opin Rheumatol 2007;19:272–6.

Dutta SB, Beg MA, Bajwa S, Kaur A, Vishal S. Prescribing pattern in rheumatoid arthritis patients in a tertiary care teaching hospital. Int J Basic Clin Pharmacol 2017;6:1486-90.

Smolen JS, Emery P, Fleischmann R, et al. Adjustment of therapy in rheumatoid arthritis on the basis of achievement of stable low disease activity with adalimumab plus methotrexate or methotrexate alone: the randomised controlled OPTIMA trial. Lancet 2014;383:321–32.

Genovese MC, Kremer J, Zamani O, et al. Baricitinib in patients with refractory rheumatoid arthritis. N Engl J Med 2016;374:1243–52.

Kostoglou-Athanassiou I, Athanassiou P, Lyraki A, Raftakis I, Antoniadis C. Vitamin D and rheumatoid arthritis. Ther Adv Endocrinol Metab 2012;3:181-7.

Feng X, Lv C, Wang F, Gan K, Zhang M, Tan W. Modulatory effect of 1,25-dihydroxyvitamin D 3 on IL1 β -induced RANKL, OPG, TNF α, and IL-6 expression in human rheumatoid synoviocyte MH7A. Clin Dev Immunol 2013;2013:1-8.

Pal CP, Singh P. Epidemiology of knee osteoarthritis in India & related factors. Indian J Orthop. 2016;50:518‐522.

Ritu G, Gupta A. Vitamin D Deficiency in India: Prevalence, Causalities and Interventions. Nutrients. 2014;6:729-775.

Sulaiman W, Seung OP, Ismail R. Patient’s Knowledge and Perception Towards the use of Non-steroidal AntiInflammatory Drugs in Rheumatology Clinic Northern Malaysia. Oman Medical Journal. 2012;27(6):505-508.

Misra DP, Agarwal V, Negi VS. Rheumatology in India: a Bird's Eye View on Organization, Epidemiology, Training Programs and Publications. J Korean Med Sci. 2016;31(7):1013-1019.

Sokka T, Mäkinen H, Hannonen P, Pincus T. Most people over age 50 in the general population do not meet ACR remission criteria or OMERACT minimal disease activity criteria for rheumatoid arthritis. Rheumatology (Oxford) 2007;46:1020-3.