Pre-clinical prediction of coronary atherosclerosis in copd by carotid artery intima media thickness
Keywords:
Carotid Intima Media Thickness (CIMT), Chronic Obstructive Pulmonary Disease (COPD), Subclinical Carotid Atherosclerosis, Coronary Atherosclerosis, Cardiovascular MorbidityAbstract
Aim and Introduction: To determine the association between Coronary atherosclerosis in Chronic Obstructive Pulmonary Disease and Carotid Artery Intima Media Thickness. The objective of the present case control study is to determine the association between carotid atherosclerosis in COPD patients and cardiovascular morbidity. Material and methods. It was a prospective case-control observational study. 50 COPD patients and 50 age- and gender-matched non-COPD controls were studied. Carotid artery USG scanning was carried out using B-mode duplex USG for measurement of carotid artery intima - media thickness. Results. CIMT was found to be more common in COPD group patients (78%) as compared to non-COPD group patients (26%) (P value = 0.000). The mean CIMT is 1.04 0.41 mm in the COPD group and 0.71 0.24 in the COPD group with a P value of 0.0001. The mean CIMT in Gold 3 was the highest (1.10 0.48 mm), followed by Gold 4 (1.05 0.46 mm) and the minimum in Gold 1 (0.73 0.00 mm). Conclusion. Our study shows that COPD is associated with increased CIMT, which is a preclinical predictor of coronary atherosclerosis and cardiovascular risk. However, further studies are needed.
Downloads
References
MacNee, William, John Maclay, & David McAllister. Cardiovascular injury and repair in chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society2008; 5 (8), 824-833.
Agustí, Alvar. Systemic effects of chronic obstructive pulmonary disease: what we know and what we don't know (but should). Proceedings of the American Thoracic Society2007 ;4(7), 522-525.
Karakas, Omer, NesatCullu, Ekrem Karakas, ZaferHasan Ali Sak, Murat Yildizhan, ErdemDaglioglu, &Ferit Dogan. Evaluation of carotid intima-media thickness in the patients with chronic obstructive pulmonary disease2013; 29, 265.
J C Mendes de Oliveira, I. d C Aguiar , A. C. N d O Beloto et. Al., Clinical significance in COPD patients followed in a real practice, Multidisciplinary Respiratory Medicine 2013;8:43 http://www.mrmjournal.com/content/8/1/43.
Julio Cesar Mendes de Oliveria et al, Clinical significance in COPD patients followed in a real practice, MultidiscipRespir Med ; 2013; 8; 43.
Adrish, Muhammad, VaralaxmiBhavaniNannaka, Edison J. Cano, Bharat Bajantri, & Gilda Diaz-Fuentes. Significance of NT-pro-BNP in acute exacerbation of COPD patients without underlying left ventricular dysfunction. International journal of chronic obstructive pulmonary disease2017;12,1183-1189.
Hafez, Manal R, EmanSobh, Omaima I. Abo-Elkheir, &Lobna K. Sakr. Atherosclerosis is associated comorbidity in patients with chronic obstructive pulmonary disease: ultrasound assessment of carotid intima media thickness. Eurasian J Pulmonol2016;18(1),165-171.
Özdemirel, TuğceŞahin et. Al., Effects of right ventricular dysfunction on exercise capacity and quality of life and associations with serum NT-proBNP levels in COPD: an observational study. Anatolian Journal of Cardiology/AnadoluKardiyoloji Dergisi2014;14(4),370-7.
Chindhi, Sandip, Surinder Thakur, Malay Sarkar, & Prakash C. Negi. Subclinical atherosclerotic vascular disease in chronic obstructive pulmonary disease: Prospective hospital-based case control study. Lung India: Official Organ of Indian Chest2015; 32(2),137-41.
V N Dhadke, S Dhadke N Raut Clinical profile in chronic obstructive pulmonary disease patients and their evaluation with spirometry and 2D ECHO.2 International Journal of Current Research2015;7(100),12480–12488.
Kim, Su Jin, D. W. Yoon, EunJoo Lee, Gyu Young Hur, K. H. Jung, Sang Yeub Lee, C. Shin et al. Carotid atherosclerosis in patients with untreated chronic obstructive pulmonary disease. The International journal of tuberculosis and lung disease2011; 15(9), 1265-1270.
KonstantinosBartziokas, Andriana I. Papaioannou, SteliosLoukides et al Serum uric acid as a predictor of mortality and future exacerbations of COPD; CHEST2008; 133(1),1088-1094.
Dr Rajani. M, Dr Manoj,D.K, Dr Smithanair, Evaluation of carotid intima- media thickness in Patients with Chronic Obstructive Pulmonary Disease; JMSCR, 2016;3(1), 9591-9598.
Pobeha P, Skyba P, Joppa P, Kluchova Z, Szaboova E, Tkac I, et al. Carotid intima-media thickness in patients with chronic obstructive pulmonary disease. BratislLekListy, 2011;112, 24-28.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
