Effect of serum magnesium, and copper in breast carcinoma patients: A comparative cross sectional study in tertiary care hospital, Madhya Pradesh, India

Nethala Ravi Kumar; Abhay John; Siddharth D. Pimpalkar; Amit Kumar Tiwari

doi:10.53730/ijhs.v6nS6.12770

Authors

Nethala Ravi Kumar
ravikumarnethala3@gmail.com
PhD Scholar, Department of Pharmacology, Index Medical College, Malwanchal University Indore, Madhya Pradesh, India
Abhay John Research Supervisor, Department of Pharmacology, Index Medical College, Malwanchal University, Indore, Madhya Pradesh, India
Siddharth D. Pimpalkar Associate Professor, Department of Microbiology, BRLSABVM Medical College, Rajnandgaon, Chattisgarh, India
Amit Kumar Tiwari Associate Professor, Department of Pathology, BRLSABVM Medical College, Rajnandgaon, Chattisgarh, India

Keywords:

serum magnesium, serum copper, breast carcinoma, biomarkers

Abstract

Background: In our country, there has been little study on breast cancer individuals during and progression of the cancer on magnesium, and copper have not been considered in existing studies. Aim: To determine the effect of serum magnesium, and copper in breast cancer subjects and to compare them with the apparently healthy controls. Methods: Lately diagnosed female subjects with breast cancer in the age group of 40-60 years were included in the study. Apparently healthy controls were selected from the group of people who were attending for annual health check-up and found to be healthy. Results: On comparison between the two groups, the present study observed that serum copper level was lower in case of apparently healthy controls than breast cancer subjects. Comparing between the groups of serum magnesium level, the present study observed significant difference. Similarly, the serum copper level was also found to be significantly differed when compared between the two groups. Conclusion: The altered values of magnesium and copper are responsible for the initiation of breast cancer. In addition, present study implies that serum copper can be used as biomarkers for early identification and diagnosis of breast cancer.

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