Study of aetiology, clinical profile and B-type natriuretic peptide levels in heart failure with preserved and reduced ejection fraction
Keywords:
aetiology, clinical profile, B-type natriuretic peptide levels, heart failureAbstract
Since from the last one decade, new cardiac biomarkers specifically BNP levels are being used widely as a marker of diagnosis, severity and prognosis of HF. A Cross Sectional Study was conducted at Department Of General Medicine, Dhiraj Hospital, Sbks MIRC, Pipariya, Vadodara with a sample size of 70. A total of 70 patients with heart failure were studied and found that 41 (58.57%) patients had reduced ejection fraction and 29 (41.43%) patients had preserved ejection fraction. In our study majority of the patients were found in NYHA Grade IV (37.14). The mean BNP levels of the whole study group is 1148.73±876.61. The mean level of BNP in HFpEF is 905.28± 823.73 and in HFrEF is 1320.93 ± 881.60. There was statistically significant difference was observed in between the two groups (p value P = 0.0499). In our present study the BNP levels are increasing with increasing NYHA severity of breathlessness (p= 0.0113). The study showed as the severity of NYHA grading increases the BNP levels increase. BNP levels tend to increase more in hypertensive patients as compared to non hypertensive patients.
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