Fungal infection in nail psoriasis
An existence to consider
Keywords:
Psoriatic nails, Onychomycosis, FrequencyAbstract
Introduction: Onychomycosis is a common superficial fungal infection of nail in both developed and developing countries. It may involve any component of the nail unit, including the nail matrix, the nail bed, or the nail plate. It represents up to 20.0% of all nail disorders. Its prevalence is estimated at 2 to 18 percentage worldwide and up to 48-percentage incidence by age 70. Onychomycosis can be caused by dermatophyte mold, yeasts and non dermatophyte mold. We planned this study to determine the frequency of onychomycosis in psoriatic nails to establish the local perspective as the international studies shows wide variation. Objective: To find the presence of fungal elements in nails of patients affected by psoriasis. Setting: Dermatology (OPD), Baqai Medical University. Duration: 06 months from 15th July 2022 - 15th Dec 2022. Design: Descriptive Cross-sectional study. Results: In this study, out of 96 cases, 32.29% (n=31) of patients were between 18-40 years and 67.71% (n=65) were between 41-70 years of age, mean+SD: 47.32+11.94 years.
Downloads
References
Alves N, Moreira TA, Malvino L, Rodrigue, JJ, Ranza R, Araújo LB et al. Onychomycosis in Psoriatic Patients with Nail Disorders: Aetiological Agents and Immunosuppressive Therapy. Dermatology research and practice. 2020:7209518.
Tabassum S, Rahman A, Awan S, Jabeen K, Farooqi J, Ahmed B, et al. Factors associated with onychomycosis in nail psoriasis: a multicenter study in Pakistan. Int J Dermatol. 2019:58(6):672-678.
Romaszkiewicz A, Bykowska B, Zabłotna M, Sobjanek M, Sławińska M, Nowicki RJ. The prevalence and etiological factors of onychomycosis in psoriatic patients. Advances in Dermatology. 2018:35(3):309-313.
A Tsentemeidou, T A Vyzantiadis, A Kyriakou, D Sotiriadis, A Patsatsi, “Prevalence of onychomycosis among patients with nail psoriasis who are not receiving immunosuppressive agents: results of a pilot study”. Mycoses. 2017:60(12):830–835.
Jendoubi F, Ben Lagha I, Rabhi F, Doss N, Mrabet A, Jaber K, et al. Nail Involvement in Psoriatic Patients and Association with Onychomycosis: Results from a Cross-Sectional Study Performed in a Military Hospital in Tunisia. Skin Appendage Disorders. 2019:5(5):299-303.
Grynszpan R, Barreiros G, Nascimento P M, Frasnelli F M, Aguinaga F, Camargo C, et al Coexistence of onychomycosis and nail psoriasis and its correlation with systemic treatment. Mycoses. 2021:64(9):1092-1097.
Klaassen K M, Dulak M G, van de Kerkhof P C, Pasch M C. The prevalence of onychomycosis in psoriatic patients: a systematic review. J Eur Acad Dermatol Venereol. 2014:28(5):533-41.
Haneke E. Differential Diagnosis of Nail Psoriasis and Onychomycoses: A Report Based on 40 Years of Specialised Nail Consultations. EMJ Dermatol. 2020:00008.
Lipner SR, Scher RK. Onychomycosis: Clinical overview and diagnosis. J Am Acad Dermatol. 2019:80(4):835-851.
Ventura A, Mazzeo M, Gaziano R, Galluzzo M, Bianchi L, Campione E. New insight into the pathogenesis of nail psoriasis and overview of treatment strategies. Drug design, development and therapy. 2017:11:2527–2535.
Gupta A K, Versteeg S G, Shear N H. Onychomycosis in the 21st Century: An Update on Diagnosis, Epidemiology, and Treatment. J Cutan Med Surg. 2017:21(6):525-539.
Gupta AK, Stec N, Summerbell RC, Shear NH, Piguet V, Tosti A, Piraccini BM. Onychomycosis: a review. J Eur Acad Dermatol Venereol. 2020 Sep;34(9):1972-1990.
Lipner SR, Scher RK. Onychomycosis: Treatment and prevention of recurrence. J Am Acad Dermatol. 2019 Apr;80(4):853-867
Gupta AK, Venkataraman M, Talukder M. Onychomycosis in Older Adults: Prevalence, Diagnosis, and Management. Drugs Aging. 2022 Mar;39(3):191-198
Gupta C, Jongman M, Das S, Snehaa K, Bhattacharya SN, Seyedmousavi S, et al. Genotyping and In Vitro Antifungal Susceptibility Testing of Fusarium Isolates from Onychomycosis in India. Mycopathologia. 2016 Aug;181((7-8)):497–504
Babayani M, Salari S, Hashemi SJ, Ghasemi Nejad Almani P, Fattahi A. Onychomycosis due to dermatophytes species in Iran: prevalence rates, causative agents, predisposing factors and diagnosis based on microscopic morphometric findings. J Mycol Med. 2018 Mar;28((1)):45–50
Leibovici V, Hershko K, Ingber A, Westerman M, Leviatan-Strauss N, Hochberg M. Increased prevalence of onychomycosis among psoriatic patients in Israel. Acta Derm Venereol. 2008;88(1):31-3.
Peng Y-T, Yu R-T, Chen A-J, Wen Z-Y, Xu J, Huang K, Wang P. Predicting the Risk of Nail Involvement in Psoriasis Patients: Development and Assessment of a Predictive Nomogram. Diagnostics. 2023; 13(4):633
Reich, K. Approach to managing patients with nail psoriasis. J. Eur. Acad. Dermatol. Venereol. 2009, 23 (Suppl. 1), 15–21
Jiaravuthisan, M.M.; Sasseville, D.; Vender, R.B.; Murphy, F.; Muhn, C.Y. Psoriasis of the nail: Anatomy, pathology, clinical presentation, and a review of the literature on therapy. J. Am. Acad. Dermatol. 2007, 57, 1–27
Alves NCPOP, Moreira TA, Malvino LDS, Rodrigues JJ, Ranza R, de Araújo LB, Pedroso RDS. Onychomycosis in Psoriatic Patients with Nail Disorders: Aetiological Agents and Immunosuppressive Therapy. Dermatol Res Pract. 2020 May 2;2020
Gallo L, Cinelli E, Fabbrocini G, Vastarella M. A 15-year retrospective study on the prevalence of onychomycosis in psoriatic vs non-psoriatic patients: A new European shift from dermatophytes towards yeast. Mycoses. 2019 Aug;62(8):659-664
Kyriakou A, Zagalioti SC, Trakatelli MG, Fotiadou C, Apalla Z, Lazaridou E, Patsatsi A. Fungal Infections and Nail Psoriasis: An Update. J Fungi (Basel). 2022 Feb 3;8(2)
Chaowattanapanit S, Pattanaprichakul P, Leeyaphan C, Chaiwanon O, Sitthinamsuwan P, Kobwanthanakun W, Hanamornroongruang S, Bunyaratavej S. Coexistence of Fungal Infections in Psoriatic Nails and their Correlation with Severity of Nail Psoriasis. Indian Dermatol Online J. 2018 Sep-Oct;9(5):314-317
Chularojanamontri L, Pattanaprichakul P, Leeyaphan C, Suphatsathienkul P, Wongdama S, Bunyaratavej S. Overall Prevalence and Prevalence Compared among Psoriasis Treatments of Onychomycosis in Patients with Nail Psoriasis and Fungal Involvement. Biomed Res Int. 2021 Dec
Wang S, Song Y, Wan Z, Chen W, Wang R, Li R. Characterisation of the nail microbiome in psoriatic and nonpsoriatic patients with onychomycosis. Mycoses. 2022 Jan;65(1):35-44
Tsentemeidou A., Vyzantiadis T.-A., Kyriakou A., Sotiriadis D., Patsatsi A. Prevalence of onychomycosis among patients with nail psoriasis who are not receiving immunosuppressive agents: results of a pilot study. Mycoses. 2017;60(12):830–835
Published
How to Cite
Issue
Section
Copyright (c) 2023 International journal of health sciences
![Creative Commons License](http://i.creativecommons.org/l/by-nc-nd/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.