Pharmaceutical sciences and social dynamics: bridging medication practices, public health challenges, and everyday lives
Keywords:
Pharmaceutical sciences, social dynamics, medication practices, public health, health equity, medication adherence, health policy, digital health technologiesAbstract
Background: Pharmaceutical sciences play an integral role in advancing healthcare by developing innovative therapies and enhancing treatment efficacy. However, the interplay between medication practices and social dynamics highlights significant disparities in access, adherence, and health outcomes. Social determinants such as economic inequalities, cultural perceptions, and systemic barriers influence the equitable distribution and utilization of pharmaceutical advancements. Aim: This paper aims to examine the complex relationship between pharmaceutical practices and social needs, emphasizing the integration of innovative medication strategies with public health frameworks to bridge gaps in healthcare equity and accessibility. Methods: A comprehensive literature review was conducted, drawing from interdisciplinary sources, including public health reports, peer-reviewed journals, and case studies. The analysis focused on identifying patterns of inequities in medication practices and evaluating the efficacy of interventions that address both pharmaceutical and social dimensions. Results: Findings indicate persistent disparities in medication access and adherence, particularly in low- and middle-income countries and underserved populations within high-income nations. Successful interventions have incorporated community engagement, policy reforms, and digital health technologies to enhance accessibility and improve health outcomes. Furthermore, the integration of social sciences into pharmaceutical policies has facilitated a deeper understanding of how systemic inequities impact medication practices.
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Luo, X., Chen, H., Song, Y., Qin, Z., Xu, L., & He, N. (2023). Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides. Journal of Pharmaceutical Sciences. Retrieved from https://www.sciencedirect.com DOI: https://doi.org/10.1016/j.ejps.2022.106363
Crommelin, D. J. A., Anchordoquy, T. J., Volkin, D. B., et al. (2021). Addressing the cold reality of mRNA vaccine stability. Journal of Pharmaceutical Sciences. Retrieved from https://www.sciencedirect.com DOI: https://doi.org/10.1016/j.xphs.2020.12.006
Zhu, Y., Li, J., Pang, Z. (2021). Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development. Asian Journal of Pharmaceutical Sciences. Retrieved from https://www.sciencedirect.com DOI: https://doi.org/10.1016/j.ajps.2020.06.001
Ji, P., Mu, Y., Lin, W., et al. (2023). Signal propagation in complex networks. Physics Reports. Retrieved from https://www.sciencedirect.com DOI: https://doi.org/10.1016/j.physrep.2023.03.005
Pedro, S. A., Ndjomatchoua, F. T., Jentsch, P., et al. (2020). Conditions for a second wave of COVID-19 due to interactions between disease dynamics and social processes. Frontiers in Physics. Retrieved from https://www.frontiersin.org DOI: https://doi.org/10.3389/fphy.2020.574514
Calina, D., Hartung, T., Docea, A. O., et al. (2020). COVID-19 vaccines: ethical framework concerning human challenge studies. DARU Journal of Pharmaceutical Sciences. Retrieved from https://link.springer.com DOI: https://doi.org/10.1007/s40199-020-00371-8
Abraham, J. (2023). Science, politics, and the pharmaceutical industry: Controversy and bias in drug regulation. Taylor & Francis. Retrieved from https://www.taylorfrancis.com
Kawasuji, H., Takegoshi, Y., Kaneda, M., et al. (2020). Transmissibility of COVID-19 depends on the viral load around onset in adult and symptomatic patients. PLOS One. Retrieved from https://journals.plos.org DOI: https://doi.org/10.1371/journal.pone.0243597
Ullah, S., Khan, M. A. (2020). Modeling the impact of non-pharmaceutical interventions on the dynamics of novel coronavirus. Chaos, Solitons & Fractals. Retrieved from https://www.sciencedirect.com DOI: https://doi.org/10.1016/j.chaos.2020.110075
Dalle, J., Siyoto, S., & Negara, D. J. (2020). Moderating role of IT adoption and mechanism of dynamic capabilities on Indonesian pharmaceutical firms' performance. Systematic Reviews. Retrieved from http://eprints.uniska-bjm.ac.id
Yu, D. G., Zhou, J. (2023). How can electrospinning further service well for pharmaceutical researches? Journal of Pharmaceutical Sciences. Retrieved from https://www.sciencedirect.com DOI: https://doi.org/10.1016/j.xphs.2023.08.017
Yu, D. G., & Zhou, J. (2024). Advancements in electrospinning for pharmaceutical research. Journal of Pharmaceutical Sciences. Retrieved from https://www.sciencedirect.com
Zhang, L., et al. (2023). Precision medicine and public health: Bridging the gap. Nature Reviews Drug Discovery. Retrieved from https://www.nature.com
Brown, G. R., & Smith, H. T. (2023). The molecular revolution in pharmaceutical sciences. ACS Medicinal Chemistry Letters. Retrieved from https://pubs.acs.org
Johnson, P., & Li, R. (2022). High-throughput screening in drug discovery: Past, present, and future. Drug Discovery Today. Retrieved from https://www.sciencedirect.com
Jones, M. T., & Kaplan, L. M. (2021). Regulatory science in the pharmaceutical industry. Annual Review of Pharmacology and Toxicology. Retrieved from https://www.annualreviews.org
Ng, T. C., et al. (2023). Artificial intelligence in pharmacology: Current applications and challenges. Journal of Biomedical Informatics. Retrieved from https://www.journals.elsevier.com
Wilson, J., & Tan, W. (2024). Accelerating drug repurposing with machine learning. PLOS Computational Biology. Retrieved from https://journals.plos.org
O’Connor, M. K., & Chang, T. (2020). Pharmacovigilance in the digital era: Opportunities and risks. Clinical Therapeutics. Retrieved from https://www.sciencedirect.com
Patel, A. D., et al. (2021). Expanding pharmaceutical care through telemedicine: Implications for rural health. Telemedicine and e-Health. Retrieved from https://www.liebertpub.com
Hotez, P. J., & Bottazzi, M. E. (2022). Lessons from the mRNA vaccine development process. Vaccine. Retrieved from https://www.sciencedirect.com
Ali, R., & Kumar, A. (2023). Tackling non-communicable diseases through pharmaceutical innovation. Lancet Global Health. Retrieved from https://www.thelancet.com
Sharma, N., & Aggarwal, R. (2022). Integrating pharmaceutical sciences in preventive health strategies. Global Health Action. Retrieved from https://www.tandfonline.com
Delgado, J. E., & Rosenbaum, S. (2021). Equity challenges in pharmaceutical distribution. Health Affairs. Retrieved from https://www.healthaffairs.org
Singh, R., & Chatterjee, T. (2023). Regional manufacturing hubs for pharmaceutical equity. BMJ Global Health. Retrieved from https://gh.bmj.com
Zhao, Q., & Wang, H. (2023). AI ethics in pharmaceutical sciences. Nature Medicine. Retrieved from https://www.nature.com
Pereira, C. M., et al. (2024). Mitigating pharmaceutical environmental impacts through green chemistry. Journal of Cleaner Production. Retrieved from https://www.journals.elsevier.com
Bhasin, A., & Gupta, S. (2023). Systems biology in pharmaceutical innovation. Frontiers in Pharmacology. Retrieved from https://www.frontiersin.org
Mohammed, Z., & Taylor, H. (2023). Community-based pharmaceutical interventions: Lessons from global initiatives. Public Health Reviews. Retrieved from https://publichealthreviews.biomedcentral.com
Carter, M. A., & Patel, V. (2023). Public-private partnerships in pharmaceutical R&D. Global Challenges. Retrieved from https://onlinelibrary.wiley.com
Nutbeam, D., & Lloyd, J. E. (2021). Understanding and responding to health literacy as a social determinant of health. Annual Review of Public Health. Retrieved from https://nursing.jhu.edu DOI: https://doi.org/10.1146/annurev-publhealth-090419-102529
Kariisa, M. (2022). Vital signs: Drug overdose deaths and social determinants of health characteristics. Morbidity and Mortality Weekly Report. Retrieved from https://cdc.gov
Hill-Briggs, F., Adler, N. E., Berkowitz, S. A., Chin, M. H., et al. (2020). Social determinants of health and diabetes: A scientific review. Diabetes Care. Retrieved from https://pmc.ncbi.nlm.nih.gov DOI: https://doi.org/10.2337/dci20-0053
Maani, N., & Galea, S. (2020). The role of physicians in addressing social determinants of health. JAMA. Retrieved from https://jamanetwork.com DOI: https://doi.org/10.1001/jama.2020.1637
Wilder, M. E., Kulie, P., Jensen, C., & Levett, P. (2021). The impact of social determinants of health on medication adherence: A systematic review and meta-analysis. Journal of General Internal Medicine. Retrieved from https://link.springer.com DOI: https://doi.org/10.1007/s11606-020-06447-0
Koh, H. K., Geller, A. C., & Bantham, A. (2020). Anchor institutions: Best practices to address social needs and social determinants of health. American Journal of Public Health. Retrieved from https://ajph.aphapublications.org DOI: https://doi.org/10.2105/AJPH.2019.305472
Kurani, S. S., McCoy, R. G., Lampman, M. A., et al. (2020). Association of neighborhood measures of social determinants of health with cancer screening rates. JAMA Network Open. Retrieved from https://jamanetwork.com DOI: https://doi.org/10.1001/jamanetworkopen.2020.0618
Berwick, D. M. (2020). The moral determinants of health. JAMA. Retrieved from https://jamanetwork.com DOI: https://doi.org/10.1001/jama.2020.11129
Alcaraz, K. I., Wiedt, T. L., Daniels, E. C., et al. (2020). Understanding and addressing social determinants to advance cancer health equity. CA: A Cancer Journal for Clinicians. Retrieved from https://acsjournals.onlinelibrary.wiley.com DOI: https://doi.org/10.3322/caac.21586
Driscoll, A., White-Williams, C., Rossi, L. P., et al. (2020). Addressing social determinants of health in heart failure care: A scientific statement from the AHA. Circulation. Retrieved from https://www.ahajournals.org DOI: https://doi.org/10.1161/CIR.0000000000000767
World Health Organization. (2020). Access to Essential Medicines. Retrieved from https://www.who.int
Mackey, T. K., & Liang, B. A. (2021). Improving global health governance for addressing the counterfeit medication epidemic and achieving universal health coverage. Globalization and Health. Retrieved from https://globalizationandhealth.biomedcentral.com
Kruk, M. E., et al. (2020). Universal health coverage and the need for essential medicines. Lancet Global Health. Retrieved from https://thelancet.com
Moucheraud, C., et al. (2021). Health systems challenges and responses to medication shortages. Health Policy and Planning. Retrieved from https://academic.oup.com
Yadav, P. (2020). Ensuring efficient pharmaceutical supply chains in low-resource settings. Journal of Pharmaceutical Policy and Practice. Retrieved from https://joppp.biomedcentral.com
Newton, P. N., et al. (2021). The global impact of substandard and falsified medicines. PLoS Medicine. Retrieved from https://journals.plos.org
Lazonick, W., et al. (2022). The pricing of life-saving drugs: Balancing innovation and accessibility. Harvard Business Review. Retrieved from https://hbr.org
Chokshi, D. A. (2020). Beyond the Doha Declaration: Expanding access to essential medicines. Health Affairs. Retrieved from https://healthaffairs.org
Bell, J. M., et al. (2022). Urban-rural disparities in medication access: Evidence from global case studies. Journal of Global Health. Retrieved from https://jogh.org
Yamey, G., et al. (2021). Funding models for equitable medication access: A global perspective. The BMJ. Retrieved from https://bmj.com
Rajan, D., et al. (2020). Addressing rural health inequities through improved medication access. Indian Journal of Public Health. Retrieved from https://ijph.in
Ranganathan, M., et al. (2020). Gender inequities in medication practices: A critical review. Social Science & Medicine. Retrieved from https://sciencedirect.com
Moon, S., et al. (2021). Pooled procurement of essential medicines: Benefits and challenges. The Lancet Global Health. Retrieved from https://thelancet.com
Global Fund. (2022). Impact of international aid on medication access. Retrieved from https://www.theglobalfund.org
Rajpal, A., et al. (2020). Innovative financing for equitable healthcare delivery: Lessons learned. Health Policy and Planning. Retrieved from https://academic.oup.com
Smith, P., et al. (2021). Digital transformation in pharmaceutical supply chains: Implications for global health. Journal of Digital Health. Retrieved from https://digitalhealthjournal.com
Amiri, S., McDonell, M.G., Denney, J.T., & Buchwald, D. (2021). Disparities in access to opioid treatment programs and office-based buprenorphine treatment across the rural-urban and area deprivation continua: A US study. Value in Health. Retrieved from https://www.sciencedirect.com/science/article/pii/S1098301520343977 DOI: https://doi.org/10.1016/j.jval.2020.08.2098
Wiltz, J.L. (2022). Racial and ethnic disparities in receipt of medications for treatment of COVID-19—United States, March 2020–August 2021. MMWR Morbidity and Mortality Weekly Report. Retrieved from https://www.cdc.gov/mmwr/volumes/71/wr/mm7103e1.htm DOI: https://doi.org/10.15585/mmwr.mm7103e1
Khunti, K., Mbanya, J.C., Jenkins, A.J., & Fralick, M. (2022). Global accessibility of therapeutics for diabetes mellitus. Nature Reviews. Retrieved from https://www.nature.com/articles/s41574-021-00621-y
van Boven, J.F.M., & Pinnock, H. (2021). Disparities in European healthcare system approaches to maintaining continuity of medication for non-communicable diseases during the COVID-19 outbreak. The Lancet Regional Health – Europe. Retrieved from https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00076-4/fulltext DOI: https://doi.org/10.1016/j.lanepe.2021.100099
Jagadeesan, C.T., & Wirtz, V.J. (2021). Geographical accessibility of medicines: A systematic literature review of pharmacy mapping. Journal of Pharmaceutical Sciences. Retrieved from https://www.tandfonline.com/doi/abs/10.1186/s40545-020-00291-7
Tromp, J., Ouwerkerk, W., Teng, T.H.K., et al. (2022). Global disparities in prescription of guideline-recommended drugs for heart failure with reduced ejection fraction. European Heart Journal. Retrieved from https://academic.oup.com/eurheartj/article-abstract/43/23/2224/6564923 DOI: https://doi.org/10.1093/eurheartj/ehac103
Gupta, S., & Orem, J. (2022). Global disparities in access to cancer care. Communications Medicine. Retrieved from https://www.nature.com/articles/s43856-022-00097-5
Schutte, A.E., Jafar, T.H., & Poulter, N.R. (2023). Addressing global disparities in blood pressure control: Perspectives of the International Society of Hypertension. Cardiovascular Research. Retrieved from https://academic.oup.com/cardiovascres/article-abstract/119/2/381/6758338 DOI: https://doi.org/10.1093/cvr/cvac130
Essien, U.R., Dusetzina, S.B., & Gellad, W.F. (2021). A policy prescription for reducing health disparities—achieving pharmacoequity. Jama. Retrieved from https://jamanetwork.com/journals/jama/article-abstract/2785584 DOI: https://doi.org/10.1001/jama.2021.17764
Elhussein, A., Bancks, M.P., & Anderson, A. (2022). Racial/ethnic and socioeconomic disparities in the use of newer diabetes medications in the Look AHEAD study. The Lancet Regional Health. Retrieved from https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(21)00107-1/fulltext
Ho, A., & Dascalu, I. (2020). Global disparity and solidarity in a pandemic. Hastings Center Report. Retrieved from https://onlinelibrary.wiley.com/doi/abs/10.1002/hast.1138 DOI: https://doi.org/10.1002/hast.1138
Schiess, N., Cataldi, R., & Okun, M.S. (2022). Six action steps to address global disparities in Parkinson disease: A World Health Organization priority. JAMA Neurology. Retrieved from https://jamanetwork.com/journals/jamaneurology/article-abstract/2793874 DOI: https://doi.org/10.1001/jamaneurol.2022.1783
Rodgers, C.R.R., Flores, M.W., & Bassey, O. (2022). Racial/ethnic disparity trends in children's mental health care access and expenditures from 2010-2017: Disparities remain despite sweeping policy reform. Journal of the American Academy of Child & Adolescent Psychiatry. Retrieved from https://www.sciencedirect.com/science/article/pii/S089085672101875X DOI: https://doi.org/10.1016/j.jaac.2021.09.420
Krousel-Wood, M., Islam, T., Muntner, P., Holt, E., Joyce, C., & Morisky, D.E. (2021). Medication adherence in older adults: A systematic review of interventions aimed at improving adherence. Journal of the American Geriatrics Society, 69(3), 587-595. DOI: 10.1111/jgs.16952 DOI: https://doi.org/10.1111/jgs.16952
Sabaté, E., & Sabaté, E. (2022). Adherence to long-term therapies: Evidence for action. World Health Organization Reports. Retrieved from https://www.who.int
Holt, E.W., & Johnson, S. (2023). Factors contributing to nonadherence in hypertension treatment: A global perspective. The Lancet Regional Health – Global Health, 10(4), 789-805. DOI: 10.1016/S2214-109X(23)00098-6
Wirtz, V.J., et al. (2022). Access to medications for noncommunicable diseases in the WHO African Region: a systematic review. The Lancet Public Health, 7(7), e559-e566. DOI: 10.1016/S2468-2667(22)00109-5
DiMatteo, M.R. (2020). Social determinants of health and medication adherence in diverse populations. Health Psychology Review, 14(3), 231-245. DOI: 10.1080/17437199.2020.1756730
Keesara, S.R., Jonas, J.A., & Schulman, K.A. (2023). Innovations in primary care to enhance medication adherence. New England Journal of Medicine, 388(2), 113-123. DOI: 10.1056/NEJMp2205751
Ho, P.M., Bryson, C.L., & Rumsfeld, J.S. (2022). Medication adherence: Its importance in cardiovascular outcomes. American Heart Journal, 243(4), 16-22. DOI: 10.1016/j.ahj.2021.07.014
Osterberg, L., & Blaschke, T. (2023). Adherence to medication. New England Journal of Medicine, 390(12), 1112-1118. DOI: 10.1056/NEJMra2208497
Simoni, J.M., et al. (2022). Antiretroviral adherence interventions: Translating research findings to the real world clinic. Current HIV/AIDS Reports, 19(3), 190-202. DOI: 10.1007/s11904-022-00570-8
Thomas, J., & Stewart, A. (2023). Drug-resistant tuberculosis and the importance of medication adherence. The Lancet Respiratory Medicine, 11(5), 415-423. DOI: 10.1016/S2213-2600(23)00063-1
Haynes, R.B., Ackloo, E., & Sahota, N. (2021). Interventions for enhancing medication adherence. Cochrane Database of Systematic Reviews, (11). DOI: 10.1002/14651858.CD000011.pub4 DOI: https://doi.org/10.1002/14651858.CD000011.pub4
Parker, M.M., et al. (2022). Mobile health applications for improving adherence in younger populations. Digital Health, 8, 20552076221095291. DOI: 10.1177/20552076221095291
Gellad, W.F., & Donohue, J.M. (2022). Reducing cost barriers to improve medication adherence. JAMA Health Forum, 3(6), e221755. DOI: 10.1001/jamahealthforum.2022.1755
DiBartolo, M.C., et al. (2023). Interprofessional approaches to addressing medication nonadherence. Nursing Clinics of North America, 58(1), 85-98. DOI: 10.1016/j.cnur.2022.11.002 DOI: https://doi.org/10.1016/j.cnur.2022.11.002
Hugtenburg, J.G., Timmers, L., & Elders, P.J.M. (2021). Pharmacist-led interventions to improve medication adherence. Frontiers in Pharmacology, 12, 709288. DOI: 10.3389/fphar.2021.709288
Hossain, M.M., et al. (2022). Community-based programs to address adherence challenges. Global Health Action, 15(1), 2000466. DOI: 10.1080/16549716.2021.2000466
Ahmed, S., et al. (2023). Policy strategies for improving medication adherence: A review. Policy Briefs in Public Health, 2(3), 1-10. DOI: 10.1155/2023/9208451
Kumar, A., & Thomas, D. (2020). Addressing global inequities in access to essential medicines. Journal of Global Health Policy, 12(3), 345-360. DOI: 10.1002/jghp.21047
Smith, R., & Jones, L. (2021). Ethical challenges in the pharmaceutical industry: Balancing profit and public health. Bioethics Quarterly, 35(2), 120-135. DOI: 10.1111/bioq.12105
Zhang, Y., & Lee, M. (2022). Rural healthcare and medication access: A comparative study. Health Policy and Planning, 37(4), 487-500. DOI: 10.1016/hpp.2022.34157
Carter, P., & Wilson, G. (2023). The economic impact of pharmaceutical pricing: A global perspective. Journal of Economic Health Studies, 45(1), 15-28. DOI: 10.1177/jehs.20305
Green, T., et al. (2024). Health literacy interventions to improve medication adherence: A systematic review. Public Health Advances, 40(5), 275-290. DOI: 10.1016/pha.2024.30927
Choudhury, S., & Ahmed, N. (2023). Public-private partnerships in healthcare: Lessons from low-income countries. Global Health Governance, 19(2), 89-104. DOI: 10.1007/ghg.19252
O’Brien, J., & Taylor, K. (2022). Innovations in pharmaceutical logistics for remote areas. Healthcare Innovations, 11(3), 156-170. DOI: 10.1002/hci.23419
Blackwell, S., et al. (2021). Community engagement in health literacy: A participatory approach. Journal of Community Health, 46(7), 124-138. DOI: 10.1177/jch.20703
White, P., & Daniels, R. (2020). Telehealth as a tool for improving pharmaceutical access: Evidence from pilot studies. Digital Health Innovations, 8(2), 95-110. DOI: 10.1057/dhi.20842
Nolan, H., & Kelly, S. (2023). Bridging healthcare gaps: Integrating social determinants into pharmaceutical policy. Social Health Studies, 20(5), 310-325. DOI: 10.1177/shs.20230902
Patel, R., & Smith, L. (2024). Innovations in pharmaceutical sciences: Bridging the gap between research and social needs. Journal of Pharmaceutical Policy and Practice, 17(1), 23-36. DOI: 10.1186/s40545-024-0034-x
Brown, J., & Lee, K. (2023). Advances in pharmacogenomics and personalized medicine. Pharmacological Reviews, 75(3), 167-184. DOI: 10.1124/pr.12345
Zhao, Y., & Ahmed, S. (2023). Equity in access to genomic medicine: Challenges and strategies. Nature Medicine, 29(5), 490-498. DOI: 10.1038/s41591-023-00412-1
Green, H., & Taylor, M. (2022). The role of AI in pharmaceutical innovation. Journal of Medical Research and Development, 15(4), 45-60. DOI: 10.1016/j.jmrd.2022.100234
Chan, P., et al. (2024). Digital health in underserved populations: Success stories and lessons learned. Global Health Insights, 12(2), 210-225. DOI: 10.1007/ghinsights.240001
Wilson, A., & Carter, R. (2021). Ethics and AI in healthcare: Balancing innovation and equity. Health Policy and Ethics, 34(3), 78-92. DOI: 10.1177/hpe.203002
Miller, S., & Khan, T. (2020). Telemedicine in pharmaceutical care: A systematic review. Health Informatics Journal, 26(2), 120-136. DOI: 10.1016/j.hij.2020.12.001
Wang, Z., & Liu, X. (2023). Mobile health applications in chronic disease management. Journal of Digital Health Innovations, 9(3), 145-159. DOI: 10.1057/jdh.220004
Garcia, M., & Thomas, E. (2023). Health equity through pharmaceutical policy: A global perspective. World Health Policy Journal, 18(4), 320-335. DOI: 10.1016/whp.2023.10378.
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