A comparative study of haemodynamic responses of butorphanol and fentanyl while surgeries
Keywords:
Heart rate, Blood pressure, Haemodynamic responses, Butorphanol, Fentanyl, Spo2, Pulse rate, surgeriesAbstract
Background: In spite of several new airway devices emerging in recent times, direct laryngoscopy and endotracheal intubation still reigns as the gold standard in airway management, Butorphanol is a morphinan chemically related to levorphanol and has mixed agonist-antagonist properties. It is more potent and it has advantage of producing less addiction and respiratory depression. Fentanyl is µ, receptor agonist, structurally related to phenylpiperidines having clinical potency ratio 50 – 100 times of morphine. It is more potent. Butorphanol tartarate is a totally synthetic narcotic antagonist analgesic, which does not require opium alkaloids for its synthesis. Aim and objectives: Comparing the haemodynamic parameters (pulse, SBP, DBP, MAP, SpO2) during general anaesthesia in patients receiving butorphanol and fentanyl. Material and Methods: This is a double-blind randomised study comparing the two opioids, fentanyl and butorphanol, was carried out in Muzaffarnagar Medical College & Hospital, Muzaffarnagar, Uttar Pradesh, India. In our study 62 cases were divided randomly into two groups. Group A patients received inj .butorphanol tartarate and Group B patients received inj fentanyl citrate. The complete data was recorded by a single observer regarding haemodynamic parameters (systolic blood pressure, diastolic blood pressure, heart rate etc.) intraoperatively as well as postoperatively.
Downloads
References
Bedford RF, Feinstein B. Hospital admission blood pressure: a predictor for hypertension following endotracheal intubation. Anaesth Analg 1980;59(5):367- 70.
Stoelting RK. Blood pressure and heart rate changes during short duration laryngoscopy for tracheal intubation: influence of viscous or intravenous lidocaine. Anaesth Analg 1978;57(2):197-9.
Martin DE, Rosenberg H, Aukburg SJ, et al. Low dose fentanyl blunts circulatory response to tracheal intubation. Anaesth Analg 1982;61(8):680-4.
Stoelting RK. Attenuation of blood pressure response to laryngoscopy and tracheal intubation with Sodium Nitroprusside. Anaesth Analg 1979;58(2):116-9.
Kamra S, Wig J, Sapru RP. Topical nitroglycerine. A safeguard against pressor response to tracheal intubation. Anaesthesia 1986;41(11):1087-91.
Mikawa K, Nishina K, Maekawa N, et al. Comparison of nicardipine, diltiazem and verapamil for controlling the cardiovascular responses to tracheal intubation. Br J Anaesth 1996;76(2):221-6.
Nami K, Takahi K, Tanaka K, et al. Comparison of landiolol and esmolol for attenuation of cardiovascular response and plasma renin activity against tracheal intubation with laryngoscopy. Anaesthesiology 2005;103:433.
Karl. Insertion of LMA in place of endotracheal intubation to attenuate the cardiovascular response. IJA 1999;43:30- 5.
Kumar. Blocking glossopharyngeal and superior laryngeal nerves to attenuate the cardiovascular response to laryngoscopy and endotracheal intubation. IJA 1993;41:20-5.
Morgan Edward, Maged S Mikhali, Michael J. Murray with C. Philip Larson, Jr. Clinical Anaesthesiology, 3rd edition.
Ronald D. Miller Anaesthesia edition 6th.
Smith JE, King MJ, Yanny HF, Pottinger KA, Pomirska MB. Effect of fentanyl on the circulatory responses to orotracheal fibreoptic intubation. Anaesthesia. 1992 Jan; 47(1):20-3.
Roscow CE. Butorphanol in perspective. Acute Care 1988; 12(suppl 1):2-7
Del Pizzo A. Butorphanol, a new intravenous analgesic: Doubie blind comparison with morphine sulfate in postoperative patients with moderate or severe pain. Current Therapeutic Research VoI.20.No.3, Sept.1976 221-232.
Pang WW, Lei CH, Chang DP, Tung CC, Huang MH. The effects of tramadol verus fentanyl in attenuating hemodynamic responsefollowing tracheal intubation. Acta Anaesthesiol Sin 1999.Dec;37(4):191-6
Bowdle TA, Greichen SL, Bjurstrom RL, Schoene RB.Butorphanol improves CO2 response and ventilation after fentanyl anaesthesia. Anaesth Analg. 1987 Jun; 66(6): 517-22.
Singh N., Verma R.K, Jaiswal S, Rao P. B: Total Intravenous Anesthesia In Laparoscopic Cholecystectomy: Comparison Of Butorphanol And Fentanyl. The Internet Journal of Anesthesiology. 2007. Volume 14 Number 1.
Sujit K. Pandit, Sarla P. Kothary, Uma A. Pandit & Mary K. Mathai, Comparison of fentanyl and butorphanol for outpatient anaesthesia Canadian Journal of Anaesthesia volume 34, pages130–134 (1987).
B K Philip 1, D A Scott, D Freiberger, R R Gibbs, C Hunt, E Murray, Butorphanol compared with fentanyl in general anaesthesia for ambulatory laparoscopy, Can J Anaesth. 1991 Mar;38(2):183-6.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
